Professor | 李华兵 | 数字化转型顾问

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Name	李华兵
Contact Information	huabing.li@yale.edu
Language ability	英语, 中文
Province	重庆

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Name

李华兵

Contact Information

huabing.li@yale.edu

Language ability

英语, 中文

Province

重庆

University/Lab Affiliation and Title	重庆医科大学
Faculty	Basic Medical Sciences
Academic Background & Achievements	2012-2017: 耶鲁大学博士后 2011-2012: 新泽西州立大学博士后 2005-2011: 新泽西州立大学博士 2002-2005: 南开大学硕士 1999-2002: 南开大学理学学士
Work Experience	2024-至今: 重庆医科大学教授 2022.3-至今: 上海交通大学医学院附属瑞金医院特聘教授 2020.5-至今: 癌基因与相关基因国家重点实验室研究组长 2019.5-至今: 上海交通大学医学院-耶鲁大学免疫代谢研究院研究员 2017.8-至今: 上海交通大学医学院上海市免疫学研究所资深研究员；耶鲁大学医学院客座助理教授
Awards	2023: 国家杰出青年科学基金 2022: 上海市卫生健康学科带头人 2018: 国家高层次海外人才青年项目 2018: 上海市“东方学者”特聘教授

University/Lab Affiliation and Title

重庆医科大学

Faculty

Basic Medical Sciences

Academic Background & Achievements

2012-2017: 耶鲁大学博士后
2011-2012: 新泽西州立大学博士后
2005-2011: 新泽西州立大学博士
2002-2005: 南开大学硕士
1999-2002: 南开大学理学学士

Work Experience

2024-至今: 重庆医科大学教授
2022.3-至今: 上海交通大学医学院附属瑞金医院特聘教授
2020.5-至今: 癌基因与相关基因国家重点实验室研究组长
2019.5-至今: 上海交通大学医学院-耶鲁大学免疫代谢研究院研究员
2017.8-至今: 上海交通大学医学院上海市免疫学研究所资深研究员；耶鲁大学医学院客座助理教授

Awards

2023: 国家杰出青年科学基金
2022: 上海市卫生健康学科带头人
2018: 国家高层次海外人才青年项目
2018: 上海市“东方学者”特聘教授

Areas of Focus	RNA修饰与表观免疫
Publications	A Treg specific long non-coding RNA maintains immune-metabolic homeostasis in ageing liver., Ding C#, Yu Z#, Sefik E#, Zhou J#, Kaffe E, Wang G, Li B, Flavell RA, Hu W, Ye Y, Li HB., 2023 tRNA-m1A modification promotes T cell expansion via efficient MYC protein synthesis., Liu Y#, Zhou J#, Li X#, Zhang X#, Shi J#, Wang X, Li H, Miao S, Chen H, He X, Dong L, Lee GR, Zhen J, Liu RJ, Su B, Ye Y, Flavell RA, Yi C, Wu Y, Li HB., 2022 RNA m6A demethylase ALKBH5 regulates the development of γδ T cells., Ding C#, Xu H#, Yu Z#, Roulis M, Qu R, Zhou J, Oh J, Crawford J, Gao Y, Jackson R, Sefik E, Li S, Wei Z, Skadow M, Yin Z, Ouyang X, Wang L, Zou Q, Su B, Hu W, Flavell R, Li HB., 2022 DENR controls JAK2 translation to induce PD-L1 expression for tumor immune evasion., Chen B#, Hu J#, Chen H, Bao R, Zhou Y, Zhan M, Ye Y, Li H, Li HB., 2022 m6A mRNA modification maintains colonic epithelial cell homeostasis via NF-κb-mediated anti-apoptotic pathway., Zhang T#, Ding C#, Chen H# Zhao J, Chen J, Chen B, Mao K, Hao Y, Roulis M, Xu H, Kluger Y, Zou Q, Ye Y, Zhan M, Flavell RA, Li HB., 2022 m6A Demethylase ALKBH5 Controls CD4+ T cell Pathogenicity and Promotes Autoimmunity., Zhou J#, Zhang X#, Hu J, Qu R, Yu Z, Xu H, Chen H, Yan L, Ding C, Zou Q, Ye Y, Wang Z, Flavell RA, Li HB., 2021 Pooled CRISPR Screening Identifies m6A as a Positive Regulator of Macrophage Activation., Tong J#, Wang X#, Liu Y#, Ren X, Wang A, Chen Z, Yao J, Mao K, Liu T, Meng FL, Pan W, Zou Q, Zhou Y, Xia Q, Flavell RA, Zhu S, Li HB., 2021 Cross-talk of Four Types of RNA Modification Writers Defines Tumor Microenvironment and Pharmacogenomic Landscape in Colorectal Cancer., Chen H#, Yao J#, Bao R, Dong Y, Zhang T, Du Y, Wang G, Ni D, Xun Z, Niu X, Ye Y, Li HB., 2021 m6A mRNA methylation sustains Treg suppressive functions., Tong J#, Cao G#, Zhang T#, Sefik E, Vesely M, Broughton J, Zhu S, Li H, Li B, Chen L, Chang HY, Su B, Flavell RA, Li HB., 2018 m6A mRNA methylation controls T cell homeostasis by targeting IL-7/STAT5/SOCS pathway., Li HB#, Tong J#, Zhu S#, Batista PJ, Duffy EE, Zhao J, Bailis W, Cao G, Kroehling L, Chen Y, Wang G, Broughton JP, Chen YG, Kluger Y, Simon MD, Chang HY, Yin Z, Flavell RA*., 2017

Areas of Focus

RNA修饰与表观免疫

Publications

A Treg specific long non-coding RNA maintains immune-metabolic homeostasis in ageing liver., Ding C#, Yu Z#, Sefik E#, Zhou J#, Kaffe E, Wang G, Li B, Flavell RA, Hu W, Ye Y, Li HB*., 2023
tRNA-m1A modification promotes T cell expansion via efficient MYC protein synthesis., Liu Y#, Zhou J#, Li X#, Zhang X#, Shi J#, Wang X, Li H, Miao S, Chen H, He X, Dong L, Lee GR, Zhen J, Liu RJ, Su B, Ye Y, Flavell RA*, Yi C*, Wu Y*, Li HB*., 2022
RNA m6A demethylase ALKBH5 regulates the development of γδ T cells., Ding C#, Xu H#, Yu Z#, Roulis M, Qu R, Zhou J, Oh J, Crawford J, Gao Y, Jackson R, Sefik E, Li S, Wei Z, Skadow M, Yin Z, Ouyang X, Wang L, Zou Q, Su B, Hu W*, Flavell R*, Li HB*., 2022
DENR controls JAK2 translation to induce PD-L1 expression for tumor immune evasion., Chen B#, Hu J#, Chen H, Bao R, Zhou Y, Zhan M*, Ye Y*, Li H*, Li HB*., 2022
m6A mRNA modification maintains colonic epithelial cell homeostasis via NF-κb-mediated anti-apoptotic pathway., Zhang T#, Ding C#*, Chen H# Zhao J, Chen J, Chen B, Mao K, Hao Y, Roulis M, Xu H, Kluger Y, Zou Q, Ye Y, Zhan M*, Flavell RA*, Li HB*., 2022
m6A Demethylase ALKBH5 Controls CD4+ T cell Pathogenicity and Promotes Autoimmunity., Zhou J#, Zhang X#, Hu J, Qu R, Yu Z, Xu H, Chen H, Yan L, Ding C, Zou Q, Ye Y, Wang Z, Flavell RA*, Li HB*., 2021
Pooled CRISPR Screening Identifies m6A as a Positive Regulator of Macrophage Activation., Tong J#, Wang X#, Liu Y#, Ren X, Wang A, Chen Z, Yao J, Mao K, Liu T, Meng FL, Pan W, Zou Q, Zhou Y, Xia Q*, Flavell RA*, Zhu S*, Li HB*., 2021
Cross-talk of Four Types of RNA Modification Writers Defines Tumor Microenvironment and Pharmacogenomic Landscape in Colorectal Cancer., Chen H#, Yao J#, Bao R, Dong Y, Zhang T, Du Y, Wang G, Ni D, Xun Z, Niu X, Ye Y*, Li HB*., 2021
m6A mRNA methylation sustains Treg suppressive functions., Tong J#, Cao G#, Zhang T#, Sefik E, Vesely M, Broughton J, Zhu S, Li H, Li B, Chen L, Chang HY, Su B, Flavell RA*, Li HB*., 2018
m6A mRNA methylation controls T cell homeostasis by targeting IL-7/STAT5/SOCS pathway., Li HB#*, Tong J#, Zhu S#, Batista PJ, Duffy EE, Zhao J, Bailis W, Cao G, Kroehling L, Chen Y, Wang G, Broughton JP, Chen YG, Kluger Y, Simon MD, Chang HY, Yin Z*, Flavell RA*., 2017

Rna 修饰表观遗传免疫免疫细胞分子机制生理病理调控功能

周源 - 北京大学

陈述亮 - 武汉大学

李笑雨 - 浙江大学

Area of Focus
Rna | 修饰 | Trna | 小Rna | 功能 | 机制 | 分子 | 生物学 | 生物化学 | 研究

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