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Zhigang Li
Basic Medical Sciences
Chongqing Medical University
Chongqing
Language: Chinese, English
G-Quadruplex
Hematopoietic Stem Cells
Homeostasis
Dna Structure
Rna Structure
Helicase
Leukemia
Stem Cell Regulation
Self-Renewal
Biological Mechanisms
Areas of Focus
- Mechanism of G-quadruplex in maintaining hematopoietic stem cell homeostasis
Work Experience
- 2017-2020 - Army Medical University First Affiliated Hospital - Assistant Researcher
- 2020-2022 - Army Medical University First Affiliated Hospital - Associate Researcher
- 2022-present - Chongqing Medical University - Associate Researcher
Academic Background & Achievements
- 2006-2010 Bachelor in Biotechnology: Guilin Medical University
- 2010-2017 PhD in Cell Biology: Wuhan University
- Hosted National Natural Science Foundation project
- Published 6 SCI papers as first author
Publications
- Essential role of Dhx16-mediated ribosome assembly in maintenance of hematopoietic stem cells., Zhigang Li, Jiankun Fan, Yalan Xiao, Wei Wang, Changlin Zhen, Junbing Pan, Weiru Wu, Yuanyuan Liu, Zhe Chen, Qinrong Yan, Hanqing Zeng, Shuyu Luo, Lun Liu, Zhanhan Tu, Xueya Zhao, Yu Hou, 2024
- Post-transcriptional regulation of DEAD-box RNA helicases in hematopoietic malignancies., Jiankun Fan, Zhigang Li, Li Pei, Yu Hou, 2024
- Zfp521 is essential for the quiescence and maintenance of adult hematopoietic stem cells under stress., Zhigang Li, Xuemei Fu, Weiru Wu, Zhilong Liu, Zhe Chen, Chengfang Zhou, Yuanyuan Liu, Mei Kuang, Fangfang Sun, Feifei Xiao, Yongxiu Huang, Xiaojun Zhang, Shijun Fan, Xingqin Huang, Guangling Zheng, Jieping Chen, Yu Hou, 2021
- Haploinsufficiency of GCP4 induces autophagy and leads to photoreceptor degeneration due to defective spindle assembly in retina., Zhigang Li, Huirong Li, Xu Xu, Lingling Wang, Bo Liu, Weixin Zheng, Lili Lian, Ying Song, Xizhong Xia, Ling Hou, Hanhua Cheng, Rongjia Zhou, 2020
- A single copy of large tumor suppressor 1 or large tumor suppressor 2 is sufficient for normal hematopoiesis., Zhigang Li, Xuemei Fu, Chengyan Chai, Fangfang Sun, Feifei Xiao, Yongxiu Huang, Kai Yao, Jieping Chen, Yu Hou, 2020
