Professor | Changdong Wang | Asia Growth Partners

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Name	Changdong Wang
Contact Information	wangchangdong@cqmu.edu.cn
Language ability	Chinese, English
Province	Chongqing

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Name

Changdong Wang

Contact Information

wangchangdong@cqmu.edu.cn

Language ability

Chinese, English

Province

Chongqing

University/Lab Affiliation and Title	Chongqing Medical University
Faculty	Basic Medical Sciences
Academic Background & Achievements	1993-1996: Enshi Medical College, Clinical Medicine 1999-2002: Wuhan University, Bachelor's in Clinical Medicine 2002-2005: Huazhong University of Science and Technology, Master's in Physiology 2005-2008: Huazhong University of Science and Technology, PhD in Biopharmaceuticals Published over 30 academic articles in journals like Bone, Experimental Cell Research, Cells, Gene & Disease, IJMS, BMC Cancer, Medical Oncology
Work Experience	2009-2015: Lecturer, Department of Biochemistry and Molecular Biology, Chongqing Medical University 2010-2011: Postdoctoral Researcher, Developmental Biology, State University of New York at Buffalo 2014-2015: Postdoctoral Researcher, Developmental Biology, State University of New York at Buffalo 2015-2021: Associate Professor, Department of Biochemistry and Molecular Biology, Chongqing Medical University 2021-present: Professor, Department of Biochemistry and Molecular Biology, Chongqing Medical University

University/Lab Affiliation and Title

Chongqing Medical University

Faculty

Basic Medical Sciences

Academic Background & Achievements

1993-1996: Enshi Medical College, Clinical Medicine
1999-2002: Wuhan University, Bachelor's in Clinical Medicine
2002-2005: Huazhong University of Science and Technology, Master's in Physiology
2005-2008: Huazhong University of Science and Technology, PhD in Biopharmaceuticals
Published over 30 academic articles in journals like Bone, Experimental Cell Research, Cells, Gene & Disease, IJMS, BMC Cancer, Medical Oncology

Work Experience

2009-2015: Lecturer, Department of Biochemistry and Molecular Biology, Chongqing Medical University
2010-2011: Postdoctoral Researcher, Developmental Biology, State University of New York at Buffalo
2014-2015: Postdoctoral Researcher, Developmental Biology, State University of New York at Buffalo
2015-2021: Associate Professor, Department of Biochemistry and Molecular Biology, Chongqing Medical University
2021-present: Professor, Department of Biochemistry and Molecular Biology, Chongqing Medical University

Areas of Focus	Primary cilia Bone development Diabetes-induced bone loss Bone tumors
Publications	Icariin Treatment Rescues Diabetes-Induced Bone Loss via Scavenging ROS and Activating Primary Cilia/Gli2/Osteocalcin Signaling Pathway, Jie Liu, Qingfeng Cheng, Xiangmei Wu, Huifang Zhu, Xiaoyan Deng, Maorong Wang, Shengyong Yang, Jie Xu, Qian Chen, Mengxue Li, Xianjun Liu, Changdong Wang, 2022 Primary cilia regulate gastric cancer-induced bone loss via cilia/Wnt/β-catenin signaling pathway, Xu J, Deng X, Wu X, Zhu H, Zhu Y, Liu J, Chen Q, Yuan C, Liu G, Wang C, 2021 Bifidobacterium infantis-Mediated Herpes Simplex Virus-TK/Ganciclovir Treatment Inhibits Cancer Metastasis in Mouse Model, Wang C, Shen Y, Ma Y, 2023 The intraflagellar transport protein IFT80 is required for cilia formation and osteogenesis, Yang S, Wang C, 2012 IFT80 is essential for chondrocyte differentiation by regulating Hedgehog and Wnt signaling pathways, Wang C, Yuan X, Yang S, 2013 Pioglitazone ameliorates neuronal damage after traumatic brain injury via the PPARg/ NF-kB/IL-6 signaling pathway, Deng Y, Jiang X, Deng X, Chen H, Xu J, Zhang Z, Liu G, Yong Z, Yuan C, Sun X, Wang C, 2019 IFT80 Improves Invasion Ability in Gastric Cancer Cell Line via ift80/p75NGFR/MMP9 Signaling, Wang R, Deng X, Yuan C, Xin H, Liu G, Zhu Y, Jiang X, Wang C, 2018 Bifidobacterial recombinant thymidine kinase-ganciclovir gene therapy system induces Fasl and TNFR2 mediated antitumor apoptosis in solid tumors, Wang C, Ma Y, Hu Q, Xie T, Wu J, Zeng F, Song F, 2016 胃癌细胞系SGC7901通过间充质干细胞（MSCs）的原纤毛调控钙信号抑制其成骨分化, 陈茜，李梦雪，王吉春，刘杰，许洁，汪长东, 2023 细胞原纤毛与人类疾病, 刘杰,许洁,陈茜,汪长东, 2021 高糖损害小鼠胚胎成骨前体细胞糖代谢并通过原纤毛/Hedgehog信号通路抑制成骨分化的研究, 刘杰,许洁,陈茜,汪长东, 2021 C反应蛋白激活原纤毛抑制成颅骨骨细胞的增殖和分化, 许洁,刘杰,汪长东, 2021 淫羊藿苷促进MC3T3-E1成骨分化通过Hedgehog信号通路, 辛红美,许洁, 汪长东, 2020 Ift20 蛋白在肺癌组织中的表达及其对肺癌A549细胞增殖, 刘革力,李飞龙,胡宁,潘嘉川,汪长东, 2015 IFT80蛋白对肿瘤影响的研究, 邓小燕,李飞龙,胡宁,潘嘉川,汪长东, 2014 IFT20蛋白在不同肿瘤组织中表达的研究, 姜容, 刘贵勇, 陈鹏, 汪长东, 2012

Areas of Focus

Primary cilia
Bone development
Diabetes-induced bone loss
Bone tumors

Publications

Icariin Treatment Rescues Diabetes-Induced Bone Loss via Scavenging ROS and Activating Primary Cilia/Gli2/Osteocalcin Signaling Pathway, Jie Liu, Qingfeng Cheng, Xiangmei Wu, Huifang Zhu, Xiaoyan Deng, Maorong Wang, Shengyong Yang, Jie Xu, Qian Chen, Mengxue Li, Xianjun Liu, Changdong Wang, 2022
Primary cilia regulate gastric cancer-induced bone loss via cilia/Wnt/β-catenin signaling pathway, Xu J, Deng X, Wu X, Zhu H, Zhu Y, Liu J, Chen Q, Yuan C, Liu G, Wang C, 2021
Bifidobacterium infantis-Mediated Herpes Simplex Virus-TK/Ganciclovir Treatment Inhibits Cancer Metastasis in Mouse Model, Wang C, Shen Y, Ma Y, 2023
The intraflagellar transport protein IFT80 is required for cilia formation and osteogenesis, Yang S, Wang C, 2012
IFT80 is essential for chondrocyte differentiation by regulating Hedgehog and Wnt signaling pathways, Wang C, Yuan X, Yang S, 2013
Pioglitazone ameliorates neuronal damage after traumatic brain injury via the PPARg/ NF-kB/IL-6 signaling pathway, Deng Y, Jiang X, Deng X, Chen H, Xu J, Zhang Z, Liu G, Yong Z, Yuan C, Sun X, Wang C, 2019
IFT80 Improves Invasion Ability in Gastric Cancer Cell Line via ift80/p75NGFR/MMP9 Signaling, Wang R, Deng X, Yuan C, Xin H, Liu G, Zhu Y, Jiang X, Wang C, 2018
Bifidobacterial recombinant thymidine kinase-ganciclovir gene therapy system induces Fasl and TNFR2 mediated antitumor apoptosis in solid tumors, Wang C, Ma Y, Hu Q, Xie T, Wu J, Zeng F, Song F, 2016
胃癌细胞系SGC7901通过间充质干细胞（MSCs）的原纤毛调控钙信号抑制其成骨分化, 陈茜，李梦雪，王吉春，刘杰，许洁，汪长东, 2023
细胞原纤毛与人类疾病, 刘杰,许洁,陈茜,汪长东, 2021
高糖损害小鼠胚胎成骨前体细胞糖代谢并通过原纤毛/Hedgehog信号通路抑制成骨分化的研究, 刘杰,许洁,陈茜,汪长东, 2021
C反应蛋白激活原纤毛抑制成颅骨骨细胞的增殖和分化, 许洁,刘杰,汪长东, 2021
淫羊藿苷促进MC3T3-E1成骨分化通过Hedgehog信号通路, 辛红美,许洁, 汪长东, 2020
Ift20 蛋白在肺癌组织中的表达及其对肺癌A549细胞增殖, 刘革力,李飞龙,胡宁,潘嘉川,汪长东, 2015
IFT80蛋白对肿瘤影响的研究, 邓小燕,李飞龙,胡宁,潘嘉川,汪长东, 2014
IFT20蛋白在不同肿瘤组织中表达的研究, 姜容, 刘贵勇, 陈鹏, 汪长东, 2012

Cilia Bone Development Diabetes Tumors Osteocalcin Signaling Pathway Research Biology

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