Areas of Focus
- 原纤毛
- 骨发育
- 糖尿病骨丢失
- 骨肿瘤
Work Experience
- 2009-2015: 重庆医科大学基础医学院生化教研室,讲师
- 2010-2011: 美国纽约州立大学布法罗分校,发育生物学,博士后
- 2014-2015: 美国纽约州立大学布法罗分校,发育生物学,博士后
- 2015-2021: 重庆医科大学基础医学院生化教研室,副教授
- 2021-至今: 重庆医科大学基础医学院生化教研室,教授
Academic Background & Achievements
- 1993-1996: 恩施医学高等专科学校,临床医学专业
- 1999-2002: 武汉大学,临床医学专业 学士
- 2002-2005: 华中科技大学同济医学院,生理学 硕士
- 2005-2008: 华中科技大学生命科学学院,生物制药 博士
- 在学术刊物Bone, Experimental cell Research, Cells, Gene&Disease, IJMS, BMC cancer, Medical oncology等发表学术文章30多篇
Publications
- Icariin Treatment Rescues Diabetes-Induced Bone Loss via Scavenging ROS and Activating Primary Cilia/Gli2/Osteocalcin Signaling Pathway, Jie Liu, Qingfeng Cheng, Xiangmei Wu, Huifang Zhu, Xiaoyan Deng, Maorong Wang, Shengyong Yang, Jie Xu, Qian Chen, Mengxue Li, Xianjun Liu, Changdong Wang, 2022
- Primary cilia regulate gastric cancer-induced bone loss via cilia/Wnt/β-catenin signaling pathway, Xu J, Deng X, Wu X, Zhu H, Zhu Y, Liu J, Chen Q, Yuan C, Liu G, Wang C, 2021
- Bifidobacterium infantis-Mediated Herpes Simplex Virus-TK/Ganciclovir Treatment Inhibits Cancer Metastasis in Mouse Model, Wang C, Shen Y, Ma Y, 2023
- The intraflagellar transport protein IFT80 is required for cilia formation and osteogenesis, Yang S, Wang C, 2012
- IFT80 is essential for chondrocyte differentiation by regulating Hedgehog and Wnt signaling pathways, Wang C, Yuan X, Yang S, 2013
- Pioglitazone ameliorates neuronal damage after traumatic brain injury via the PPARg/ NF-kB/IL-6 signaling pathway, Deng Y, Jiang X, Deng X, Chen H, Xu J, Zhang Z, Liu G, Yong Z, Yuan C, Sun X, Wang C, 2019
- IFT80 Improves Invasion Ability in Gastric Cancer Cell Line via ift80/p75NGFR/MMP9 Signaling, Wang R, Deng X, Yuan C, Xin H, Liu G, Zhu Y, Jiang X, Wang C, 2018
- Bifidobacterial recombinant thymidine kinase-ganciclovir gene therapy system induces Fasl and TNFR2 mediated antitumor apoptosis in solid tumors, Wang C, Ma Y, Hu Q, Xie T, Wu J, Zeng F, Song F, 2016
- 胃癌细胞系SGC7901通过间充质干细胞(MSCs)的原纤毛调控钙信号抑制其成骨分化, 陈茜,李梦雪,王吉春,刘杰,许洁,汪长东, 2023
- 细胞原纤毛与人类疾病, 刘杰,许洁,陈茜,汪长东, 2021
- 高糖损害小鼠胚胎成骨前体细胞糖代谢并通过原纤毛/Hedgehog信号通路抑制成骨分化的研究, 刘杰,许洁,陈茜,汪长东, 2021
- C反应蛋白激活原纤毛抑制成颅骨骨细胞的增殖和分化, 许洁,刘杰,汪长东, 2021
- 淫羊藿苷促进MC3T3-E1成骨分化通过Hedgehog信号通路, 辛红美,许洁, 汪长东, 2020
- Ift20 蛋白在肺癌组织中的表达及其对肺癌A549细胞增殖, 刘革力,李飞龙,胡宁,潘嘉川,汪长东, 2015
- IFT80蛋白对肿瘤影响的研究, 邓小燕,李飞龙,胡宁,潘嘉川,汪长东, 2014
- IFT20蛋白在不同肿瘤组织中表达的研究, 姜容, 刘贵勇, 陈鹏, 汪长东, 2012