Professor | Jian-Fei Pei | Asia Growth Partners

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Name	Jian-Fei Pei
Contact Information	jamffypei@163.com
Language ability	Chinese, English
Province	Liaoning

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Name

Jian-Fei Pei

Contact Information

jamffypei@163.com

Language ability

Chinese, English

Province

Liaoning

University/Lab Affiliation and Title	China Medical University
Faculty	Life Sciences
Academic Background & Achievements	2016 - PhD in Biochemistry and Molecular Biology: Tsinghua University Revealed a new theoretical model for biological rhythm regulation Proposed new strategies for treating aging-related cardiovascular diseases Identified molecular mechanisms of susceptibility to abdominal aortic aneurysm due to aging
Work Experience	2016-2021 - Chinese Academy of Medical Sciences, National Key Laboratory of Medical Molecular Biology - Researcher 2021-present - China Medical University, Department of Medical Genetics - Associate Researcher, Doctoral Supervisor, Independent PI
Awards	National Gold Award for Undergraduate Innovation and Entrepreneurship Competition

University/Lab Affiliation and Title

China Medical University

Faculty

Life Sciences

Academic Background & Achievements

2016 - PhD in Biochemistry and Molecular Biology: Tsinghua University
Revealed a new theoretical model for biological rhythm regulation
Proposed new strategies for treating aging-related cardiovascular diseases
Identified molecular mechanisms of susceptibility to abdominal aortic aneurysm due to aging

Work Experience

2016-2021 - Chinese Academy of Medical Sciences, National Key Laboratory of Medical Molecular Biology - Researcher
2021-present - China Medical University, Department of Medical Genetics - Associate Researcher, Doctoral Supervisor, Independent PI

Awards

National Gold Award for Undergraduate Innovation and Entrepreneurship Competition

Areas of Focus	Transcription-Translation Feedback Loop (TTFL) in Eukaryotic Circadian Rhythms Molecular Mechanisms of Cardiovascular Events with 24-hour Rhythmicity Role of Redox Oscillation Rhythms in Mammalian Aging
Publications	Diurnal oscillations of endogenous H2O2 sustained by p66Shc regulate circadian clocks, Jian-Fei Pei, Xun-Kai Li, Wen-Qi Li, Qian Gao, Yang Zhang, Xiao-Man Wang, Jia-Qi Fu, Shen-Shen Cui, Jia-Hua Qu, Xiang Zhao, De-Long Hao, Dapeng Ju, Na Liu, Kate S. Caroll, Jing Yang, Eric Erquan Zhang, Ji-Min Cao, Hou-Zao Chen, De-Pei Liu, 2019 The paraoxonase gene cluster protects against abdominal aortic aneurysm formation, Yun-Fei Yan, Jian-Fei Pei, Yang Zhang, Ran Zhang, Fang Wang, Peng Gao, Zhu-Qin Zhang, Ting-Ting Wang, Zhi-Gang She, Hou-Zao Chen, De-Pei Liu, 2017 Age-associated sirtuin 1 reduction in vascular smooth muscle links vascular senescence and inflammation to abdominal aortic aneurysm, Hou-Zao Chen, Fang Wang, Peng Gao, Jian-Fei Pei, Yue Liu, Ting-Ting Xu, Xiaoqiang Tang, Wen-Yan Fu, Jie Lu, Yun-Fei Yan, Xiao-Man Wang, Lei Han, Zhu-Qin Zhang, Ran Zhang, Ming-Hui Zou, De-Pei Liu, 2016 Human paraoxonase gene cluster overexpression alleviates angiotensin II-induced cardiac hypertrophy in mice, Jian-Fei Pei, Yun-Fei Yan, Xiaoqiang Tang, Yang Zhang, Shen-Shen Cui, Zhu-Qin Zhang, Hou-Zao Chen, De-Pei Liu, 2016

Areas of Focus

Transcription-Translation Feedback Loop (TTFL) in Eukaryotic Circadian Rhythms
Molecular Mechanisms of Cardiovascular Events with 24-hour Rhythmicity
Role of Redox Oscillation Rhythms in Mammalian Aging

Publications

Diurnal oscillations of endogenous H2O2 sustained by p66Shc regulate circadian clocks, Jian-Fei Pei, Xun-Kai Li, Wen-Qi Li, Qian Gao, Yang Zhang, Xiao-Man Wang, Jia-Qi Fu, Shen-Shen Cui, Jia-Hua Qu, Xiang Zhao, De-Long Hao, Dapeng Ju, Na Liu, Kate S. Caroll, Jing Yang, Eric Erquan Zhang, Ji-Min Cao, Hou-Zao Chen, De-Pei Liu, 2019
The paraoxonase gene cluster protects against abdominal aortic aneurysm formation, Yun-Fei Yan, Jian-Fei Pei, Yang Zhang, Ran Zhang, Fang Wang, Peng Gao, Zhu-Qin Zhang, Ting-Ting Wang, Zhi-Gang She, Hou-Zao Chen, De-Pei Liu, 2017
Age-associated sirtuin 1 reduction in vascular smooth muscle links vascular senescence and inflammation to abdominal aortic aneurysm, Hou-Zao Chen, Fang Wang, Peng Gao, Jian-Fei Pei, Yue Liu, Ting-Ting Xu, Xiaoqiang Tang, Wen-Yan Fu, Jie Lu, Yun-Fei Yan, Xiao-Man Wang, Lei Han, Zhu-Qin Zhang, Ran Zhang, Ming-Hui Zou, De-Pei Liu, 2016
Human paraoxonase gene cluster overexpression alleviates angiotensin II-induced cardiac hypertrophy in mice, Jian-Fei Pei, Yun-Fei Yan, Xiaoqiang Tang, Yang Zhang, Shen-Shen Cui, Zhu-Qin Zhang, Hou-Zao Chen, De-Pei Liu, 2016

Circadian Rhythms Eukaryotic Ttfl Feedback Loop Cardiovascular Molecular Mechanisms Aging Redox Oscillation Biological Rhythms Gene Expression

Le Rongrong - Tongji University

Changdong Lin - Tongji University

Fanglin Sun - Tongji University

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