2003.9-2007.7 Bachelor in Basic Medicine: Harbin Medical University
2007.9-2011.6 PhD in Biophysics (Bioinformatics): Harbin Medical University
Published over 60 research papers, 30 as first/corresponding author
Recipient of Heilongjiang Province Science and Technology Award (Third Prize)
Recipient of Heilongjiang Province Medical and Health Science and Technology Award (Second Prize)
2011.7-2012.8 Lecturer in Computational Systems Biology: Harbin Medical University
2012.9-2017.8 Associate Professor in Computational Systems Biology: Harbin Medical University
2017.9-present Professor in Computational Systems Biology: Harbin Medical University
June 2020: Heilongjiang Province Medical and Health Science and Technology Award (Second Prize)
October 2017: Heilongjiang Province Science and Technology Award (Third Prize)
March 2017: Harbin Medical University Young Scientific Talent Award
November 2016: Harbin Science and Technology Progress Award (Third Prize)
October 2016: Harbin Medical University 'Three Educations' Advanced Individual
Research
Bioinformatics of Complex Diseases Cancer Genomics Drug Resistance Mechanisms
Identification of mutational signature for lung adenocarcinoma prognosis and immunotherapy prediction, Sainan Zhang, Mengyue Li, Yilong Tan, Juxuan Zhang, Yixin Liu, Wenbin Jiang, Xin Li, Haitao Qi, Lefan Tang, Ran Ji, Wenyuan Zhao, Yunyan Gu, Lishuang Qi, 2022
A genetic map of the chromatin regulators to drug response in cancer cells, Bo Chen, Pengfei Li, Mingyue Liu, Kaidong Liu, Min Zou, Yiding Geng, Shuping Zhuang, Huanhuan Xu, Linzhu Wang, Tingting Chen, Yawei Li, Zhangxiang Zhao, Lishuang Qi, Yunyan Gu, 2022
Upregulation of CXCL1 and LY9 contributes to BRCAness in ovarian cancer and mediates response to PARPi and immune checkpoint blockade, Tingting Chen, Tong Yu, Shuping Zhuang, Yiding Geng, Junwen Xue, Jiayi Wang, Liqiang Ai, Bo Chen, Zhangxiang Zhao, Yawei Li, Jinghao Wang, Haihai Liang, Yan Xu, Yunyan Gu, 2022
Systematic exploration of the underlying mechanism of gemcitabine resistance in pancreatic adenocarcinoma, Kaidong Liu, Yiding Geng, Linzhu Wang, Huanhuan Xu, Min Zou, Yawei Li, Zhangxiang Zhao, Tingting Chen, Fengyan Xu, Liang Sun, Shuliang Wu, Yunyan Gu, 2022
StemSC: a cross-dataset human stemness index for single-cell samples, Hailong Zheng, Jiajing Xie, Kai Song, Jing Yang, Huiting Xiao, Jiashuai Zhang, Keru Li, Rongqiang Yuan, Yuting Zhao, Yunyan Gu, Wenyuan Zhao, 2022
Pan-cancer multi-omics analyses reveal crosstalk between the Hippo and immune signaling pathways in the tumor microenvironment, Chengyu Wang, Tong Zhu, Zhangxiang Zhao, Bo Chen, Tingting Chen, Qi Dong, Mingyue Liu, Shuping Zhuang, Fan Yang, Yaoyao Liu, Min Yang, Yunyan Gu, Haihai Liang, 2022
A transcriptional signature detects homologous recombination deficiency in pancreatic cancer at the individual level, Shuping Zhuang, Tingting Chen, Yawei Li, Yuquan Wang, Liqiang Ai, Yiding Geng, Min Zou, Kaidong Liu, Huanhuan Xu, Linzhu Wang, Zhangxiang Zhao, Zhiqiang Chang, Yunyan Gu, 2021
Discovering a qualitative transcriptional signature of homologous recombination defectiveness for prostate cancer, Yawei Li, Zhangxiang Zhao, Liqiang Ai, Yuquan Wang, Kaidong Liu, Bo Chen, Tingting Chen, Shuping Zhuang, Huanhuan Xu, Min Zou, Yunyan Gu, Xia Li, 2021
Revealing biomarkers associated with PARP inhibitors based on genetic interactions in cancer genome, Qi Dong, Mingyue Liu, Bo Chen, Zhangxiang Zhao, Tingting Chen, Chengyu Wang, Shuping Zhuang, Yawei Li, Yuquan Wang, Liqiang Ai, Yaoyao Liu, Haihai Liang, Lishuang Qi, Yunyan Gu, 2021
Individualized lncRNA differential expression profile reveals heterogeneity of breast cancer, Zhangxiang Zhao, YingYing Guo, Yaoyao Liu, Lichun Sun, Bo Chen, Chengyu Wang, Tingting Chen, Yuquan Wang, Yawei Li, Qi Dong, Liqiang Ai, Ran Wang, Yunyan Gu, Xia Li, 2021
LncRNA CTD-2528L19.6 prevents the progression of IPF by alleviating fibroblast activation, Tingting Chen, Yingying Guo, Jiayi Wang, Liqiang Ai, Lu Ma, Wenxin He, Zhixin Li, Xiaojiang Yu, Jinrui Li, Xingxing Fan, Yunyan Gu, Haihai Liang, 2021
An individualized transcriptional signature to predict the epithelial-mesenchymal transition based on relative expression ordering, Tingting Chen, Zhangxiang Zhao, Bo Chen, Yuquan Wang, Fan Yang, Chengyu Wang, Qi Dong, Yaoyao Liu, Haihai Liang, Wenyuan Zhao, Lishuang Qi, Yan Xu, Yunyan Gu, 2020
A PTAL-miR-101-FN1 axis promotes EMT and invasion-metastasis in serous ovarian cancer, Haihai Liang, Mengxue Yu, Rui Yang, Lu Zhang, Lijia Zhang, Di Zhu, Hongwei Luo, Yaozhen Hong, Tong Yu, Jian Sun, Hongli Shan, Yunyan Gu, 2019
RHPCG: a database of the Regulation of the Hippo Pathway in Cancer Genome, Chengyu Wang, Fan Yang, Tingting Chen, Qi Dong, Zhangxiang Zhao, Yaoyao Liu, Bo Chen, Haihai Liang, Huike Yang, Yunyan Gu, 2019
Genetic interactions-based biomarkers identification for drug resistance and sensitivity in cancer cells, Yue Han, Chengyu Wang, Qi Dong, Tingting Chen, Fan Yang, Yaoyao Liu, Bo Chen, Zhangxiang Zhao, Lishuang Qi, Wenyuan Zhao, Haihai Liang, Zheng Guo, Yunyan Gu, 2019
Link synthetic lethality to drug sensitivity of cancer cells, Ruiping Wang, Yue Han, Zhangxiang Zhao, Fan Yang, Ya Han, Tingting Chen, Xianlong Wang, Lishuang Qi, Wenyuan Zhao, Zheng Guo, Yunyan Gu, 2019
LncRNA PTAR promotes EMT and invasion-metastasis in serous ovarian cancer by competitively binding miR-101-3p to regulate ZEB1 expression, Haihai Liang, Tong Yu, Yue Han, Hua Jiang, Chengyu Wang, Tianiyi You, Xiaoguang Zhao, Huitong Shan, Rui Yang, Lida Yang, Hongli Shan, Yunyan Gu, 2018
A landscape of synthetic viable interactions in cancer, Yunyan Gu, Ruiping Wang, Yue Han, Wenbin Zhou, Zhangxiang Zhao, Tingting Chen, Yuanyuan Zhang, Fuduan Peng, Haihai Liang, Lishuang Qi, Wenyuan Zhao, Da Yang, Zheng Guo, 2018
Systematic analyses reveal long non-coding RNA (PTAF)-mediated promotion of EMT and invasion-metastasis in serous ovarian cancer, Haihai Liang, Xiaoguang Zhao, Chengyu Wang, Jian Sun, Yingzhun Chen, Guoyuan Wang, Lei Fang, Rui Yang, Mengxue Yu, Yunyan Gu, Hongli Shan, 2018
Identification of driver copy number alterations in diverse cancer types and application in drug repositioning, Wenbin Zhou, Zhangxiang Zhao, Ruiping Wang, Yue Han, Chengyu Wang, Fan Yang, Ya Han, Haihai Liang, Lishuang Qi, Chenguang Wang, Zheng Guo, Yunyan Gu, 2017
Differential expression analysis at the individual level reveals a lncRNA prognostic signature for lung adenocarcinoma, Fuduan Peng, Ruiping Wang, Yuanyuan Zhang, Zhangxiang Zhao, Wenbin Zhou, Zhiqiang Chang, Haihai Liang, Wenyuan Zhao, Lishuang Qi, Zheng Guo, Yunyan Gu, 2017
The BRCA1/2-directed miRNA signature predicts a good prognosis in ovarian cancer patients with wild-type BRCA1/2, Yunyan Gu, Mengmeng Zhang, Fuduan Peng, Lei Fang, Yuanyuan Zhang, Haihai Liang, Wenbin Zhou, Lu Ao, Zheng Guo, 2015
Integrated analyses identify the involvement of microRNA-26a in epithelial-mesenchymal transition during idiopathic pulmonary fibrosis, Haihai Liang, Yunyan Gu, Tianyu Li, Ying Zhang, Longtao Huangfu, Meiyu Hu, Dandan Zhao, Yang Chen, Shanshan Liu, Yuechao Dong, Li Xuelian, Lu Yanjie, Yang Baofeng, Shan Hongli, 2014
Network analysis of genomic alteration profiles reveals co-altered functional modules and driver genes for glioblastoma, Yunyan Gu, Hongwei Wang, Yao Qin, Yujing Zhang, Wenyuan Zhao, Lishuang Qi, Yuannv Zhang, Chenguang Wang, Zheng Guo, 2013
