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Jia Yu
j-yu@ibms.pumc.edu.cn
English, Chinese
Beijing
Peking Union Medical College
Basic Medical Sciences
  • 2006 - PhD in Biochemistry and Molecular Biology: Chinese Academy of Medical Sciences/Beijing Union Medical College
  • 2017 - National Science Fund for Distinguished Young Scholars
  • 2017 - Changjiang Scholars Program
  • 2019 - National-level candidate of the Ten Thousand Talents Program
  • 2020 - State Council Special Allowance
  • 2006-2007 - University of Illinois at Chicago - Post-doc
  • 2007-2009 - Northwestern University Feinberg School of Medicine - Post-doc
  • 2009-present - Chinese Academy of Medical Sciences - Researcher
  • 2018 - Second Prize of the Ministry of Education Natural Science Award
RNA and Stem Cell Biology
  • m6A Reader YTHDF1-Targeting Engineered Small Extracellular Vesicles for Gastric Cancer Therapy via Epigenetic and Immune Regulation, Qing You, Fang Wang, Rong Du, Jingnan Pi, Huayi Wang, Yue Huo, Jingyi Liu, Chen Wang, Jia Yu, Yanlian Yang, Ling Zhu, 2022
  • Dissecting Heterogeneity Reveals a Unique BAMBIhigh MFGE8high Subpopulation of Human UC-MSCs, Hongwei Chen, Xin Wen, Shanshan Liu, Tian Sun, Hua Song, Fang Wang, Jiayue Xu, Yueyang Zhang, Yuanjin Zhao, Jia Yu, Lingyun Sun, 2022
  • METTL3 preferentially enhances non-m6A translation of epigenetic factors and promotes tumourigenesis, Xueju Wei, Yue Huo, Jingnan Pi, Yufeng Gao, Shuan Rao, Manman He, Qinglv Wei, Peng Song, Yiying Chen, Dongxu Lu, Wei Song, Junbo Liang, lingjie Xu, Haixia Wang, Guolin Hong, Yuehong Guo, Yanmin Si, Jiayue Xu, Xiaoshuang Wang, Yanni Ma, Shuyang Yu, Dongling Zou, Jing Jin, Fang Wang, Jia Yu, 2022
  • Single-cell architecture and functional requirement of alternative splicing during hematopoietic stem cell formation, Fang Wang, Puwen Tan, Pengcheng Zhang, Yue Ren, Jie Zhou, Yunqiao Li, Siyuan Hou, Shuaili Li, Linlin Zhang, Yanni Ma, Chaojie Wang, Wanbo Tang, Xiaoshuang Wang, Yue Huo, Yongfei Hu, Tianyu Cui, Chao Niu, Dong Wang, Bing Liu, Yu Lan, Jia Yu, 2022
  • Pseudogenes and their potential functions in hematopoiesis, Yanni Ma, Zhongyang Chen, Jia Yu, 2021
  • A comprehensive RNA editome reveals that edited Azin1 partners with DDX1 to enable hematopoietic stem cell differentiation, Fengjiao Wang, Jiahuan He, Siqi Liu, Ai Gao, Liu Yang, Guohuan Sun, Wanqiu Ding, Chuanyun Li, Fanglin Gou, Manman He, Fang Wang, Xiaoshuang Wang, Xiangnan Zhao, Ping Zhu, Shao Hao, Yanni Ma, Hui Cheng, Jia Yu, Tao Cheng, 2021
  • A global screening identifies chromatin-enriched RNA-binding proteins and the transcriptional regulatory activity of QKI5 during monocytic differentiation, Yue Ren, Yue Huo, Weiqian Li, Manman He, Siqi Liu, Jiabing Yang, Hongmei Zhao, Lingjie Xu, Yuehong Guo, Yanmin Si, Hualu Zhao, Shuan Rao, Jing Wang, Yanni Ma, Xiaoshuang Wang, Jia Yu, Fang Wang, 2021
  • YTHDF1 promotes gastric carcinogenesis through controlling the translation of FZD7, Jingnan Pi, Wen Wang, Ming Ji, Xiaoshuang Wang, Xueju Wei, Jing Jin, Tao Liu, Jiaqi Qiang, Zhihong Qi, Feng Li, Yue Liu, Yanni Ma, Yanmin Si, Yue Huo, Yufeng Gao, Yiying Chen, Lei Dong, Rui Su, Jianjun Chen, Shuan Rao, Ping Yi, Shuyang Yu, Fang Wang, Jia Yu, 2021
  • Genome-wide analysis of pseudogenes reveals HBBP1's human-specific essentiality in erythropoiesis and implication in β-thalassemia, Yanni Ma, Siqi Liu, Jie Gao, Chunyan Chen, Xin Zhang, Hao Yuan, Zhongyang Chen, Xiaolin Yin, Chenguang Sun, Yanan Mao, Fanqi Zhou, Yi Shao, Qian Liu, Jiayue Xu, Li Cheng, Daqi Yu, Pingping Li, Ping Yi, Jiahuan He, Guangfeng Geng, Qing Guo, Yanmin Si, Hualu Zhao, Haipeng Li, Graham L Banes, He Liu, Yukio Nakamura, Ryo Kurita, Yue Huang, Xiaoshuang Wang, Fang Wang, Gang Fang, James Douglas Engel, Lihong Shi, Yong E Zhang, Jia Yu, 2021
  • hnRNPLL controls pluripotency exit of embryonic stem cells by modulating alternative splicing of Tbx3 and Bptf, Xue Wang, Changyun Ping, Puwen Tan, Chenguang Sun, Guang Liu, Tao Liu, Shuchun Yang, Yanmin Si, Lijun Zhao, Yongfei Hu, Yuyan Jia, Xiaoshuang Wang, Meili Zhang, Fang Wang, Dong Wang, Jia Yu, Yanni Ma, Yue Huang, 2021
  • Panoramic transcriptome analysis and functional screening of long noncoding RNAs in mouse spermatogenesis, Kai Li, Jiayue Xu, Yanyun Luo, Dingfeng Zou, Ruiqin Han, Shunshun Zhong, Qing Zhao, Xinyu Mang, Mengzhen Li, Yanmin Si, Yan Lu, Pengyu Li, Cheng Jin, Zhipeng Wang, Fang Wang, Shiying Miao, Bo Wen, Linfang Wang, Yanni Ma, Jia Yu, Wei Song, 2021
  • Transcriptomic analysis reveals a tumor subtype-mRNA classifier for invasive non-functioning pituitary adenoma diagnostics, Xinjie Bao, Gengchao Wang, Shan Yu, Jian Sun, Hualu Zhao, Yanni Ma, Fang Wang, Xiaoshuang Wang, Renzhi Wang, Jia Yu, 2021
  • The m6A reader YTHDF1 promotes ovarian cancer progression via augmenting EIF3C translation, Tao Liu, Qinglv Wei, Jing Jin, Qingya Luo, Yi Liu, Yu Yang, Chunming Cheng, Lanfang Li, Jingnan Pi, Yanmin Si, Hualiang Xiao, Li Li, Shuan Rao, Fang Wang, Jianhua Yu, Jia Yu, Dongling Zou, Ping Yi, 2020
  • microRNA arm-imbalance partially from targets-mediated decay promotes gastric cancer progression, Zhengyi Zhang, Jingnan Pi, Dongling Zou, Xiaoshuang Wang, Jiayue Xu, Shan Yu, Ting Zhang, Feng Li, Hualu Zhao, Fang Wang, Dong Wang, Yanni Ma, Jia Yu, 2019
  • Combined Single-Cell Profiling of lncRNAs and Functional Screening Reveals that H19 Is Pivotal for Embryonic Hematopoietic Stem Cell Development, Jie Zhou, Jiayue Xu, Lingling Zhang, Siqi Liu, Yanni Ma, Xin Wen, Junkai Hao, Zongcheng Li, Yanli Ni, Xianlong Li, Fan Zhou, Qingqing Li, Fang Wang, Xiaoshuang Wang, Yanmin Si, Pengcheng Zhang, Chen Liu, Marisa Bartolomei, Fuchou Tang, Bing Liu, Jia Yu, Yu Lan, 2019
  • Late-stage tumors induce anemia and immunosuppressive extramedullary erythroid progenitor cells, Lintao Zhao, Ran He, Haixia Long, Bo Guo, Qingzhu Jia, Diyuan Qin, Si-Qi Liu, Zhongyu Wang, Tong Xiang, Jue Zhang, Yulong Tan, Jiani Huang, Junying Chen, Fang Wang, Minglu Xiao, Jianbao Gao, Xinxin Yang, Hao Zeng, Xinxin Wang, Chunyan Hu, Peter B. Alexander, Alistair L. J. Symonds, Jia Yu, Yisong Wan, Qi-Jing Li, Lilin Ye, Bo Zhu, 2018
  • Long non-coding RNAs in hematopoietic regulation, Weiqian Li, Yue Ren, Yanmin Si, Fang Wang, Jia Yu, 2018
  • KSRP specifies monocytic and granulocytic differentiation through regulating miR-129 biogenesis and RUNX1 expression, Hongmei Zhao, Xiaoshuang Wang, Ping Yi, Yanmin Si, Puwen Tan, Jinrong He, Shan Yu, Yue Ren, Yanni Ma, Junwu Zhang, Dong Wang, Fang Wang, Jia Yu, 2017
  • Single-cell RNA sequencing highlights transcription activity of autophagy-related genes during hematopoietic stem cell formation in mouse embryos, Yongfei Hu, Yan Huang, Ying Yi, Hongwei Wang, Bing Liu, Jia Yu, Dong Wang, 2017
  • The RNA-binding protein QKI5 regulates primary miR-124-1 processing via a distal RNA motif during erythropoiesis, Fang Wang, Wei Song, Hongmei Zhao, Yanni Ma, Yuxia Li, Di Zhai, Jingnan Pi, Yanmin Si, Jiayue Xu, Lei Dong, Rui Su, Mengmeng Zhang, Yong Zhu, Xiaoxia Ren, Fei Miao, Wenjie Liu, Feng Li, Junwu Zhang, Aibin He, Ge Shan, Jingyi Hui, Linfang Wang, Jia Yu, 2017
  • RAID v2.0: an updated resource of RNA-associated interactions across organisms, Ying Yi, Yue Zhao, Chunhua Li, Lin Zhang, Huiying Huang, Yana Li, Lanlan Liu, Ping Hou, Tianyu Cui, Puwen Tan, Yongfei Hu, Ting Zhang, Yan Huang, Xiaobo Li, Jia Yu, Dong Wang, 2017
  • MicroRNA-23a, -27a and -24 synergistically regulate JAK1/Stat3 cascade and serve as novel therapeutic targets in human acute erythroid leukemia, Rui Su, Lei Dong, Dongling Zou, Hongmei Zhao, Yue Ren, Feng Li, Ping Yi, Lanfang Li, Yong Zhu, Yanni Ma, Jing Wang, Fang Wang, Jia Yu, 2016
  • Functional screen reveals essential roles of miR-27a/24 in differentiation of embryonic stem cell, Yanni Ma, Nan Yao, Guang Liu, Lei Dong, Fang Wang, Bin Wang, He Dong, Xueju Wei, Meili Zhang, Shaowei Ji, Yufang Liu, Junwu Zhang, Yangming Wang, Yue Huang, Jia Yu, 2015
  • A Feedback Loop Consisting of MicroRNA 23a/27a and the Beta-Like Globin Suppressors KLF3 and SP1 Regulates Globin Gene Expression, Yanni Ma, Bin Wang, Fengbing Jiang, Dongsheng Wang, Huiwen Liu, Yunmeng Yan, He Dong, Fang Wang, Bei Gong, Yong Zhu, Lei Dong, Haixin Yin, Zhongzu Zhang, Hualu Zhao, Zhikui Wu, Junwu Zhang, Jingguo Zhou, Jia Yu, 2013
  • A comprehensive analysis of GATA-1-regulated miRNAs reveals miR-23a to be a positive modulator of erythropoiesis, Yong Zhu, Dongsheng Wang, Fang Wang, Tingting Li, Lei Dong, Huiwen Liu, Yanni Ma, Fengbing Jiang, Haixin Yin, Wenting Yan, Ming Luo, Z Tang, Guoyuan Zhang, Qiang Wang, Junwu Zhang, Jingguo Zhou, Jia Yu, 2013
  • Recent progress in microRNA study: Benefits from technique advance, Jia Yu, Fang Wang, 2012
  • MicroRNA-29a and microRNA-142-3p are regulators of myeloid differentiation and acute myeloid leukemia, Xiaoshuang Wang, Jianan Gong, Jia Yu, Fang Wang, Xinhua Zhang, Xiaolin Yin, Zhenqing Tan, Zimian Luo, Guihua Yang, Chao Shen, Junwu Zhang, 2012
  • Regulation of erythroid differentiation by miR-376a and its targets, Fang Wang, Jia Yu, Guihua Yang, Xiaoshuang Wang, Junwu Zhang, 2011
  • MicroRNA-205 promotes keratinocyte migration via the lipidphosphatase SHIP2, Jia Yu, Han Peng, Qing Ruan, Anees Fatima, Spiro Getsios, Robert M. Lavker, 2010
  • MiRNA-96 suppresses KRAS and functions as a tumor suppressor gene in pancreatic cancer, Shuangni Yu, Zhaohui Lu, Changzheng Liu, Yunxiao Meng, Yihui Ma, Wugan Zhao, Jianping Liu, Jia Yu, Jie Chen, 2010
  • MicroRNA-21 acts as an oncomir through multiple targets in human hepatocellular carcinoma, Changzheng Liu, Jia Yu, Shuangni Yu, Robert M.Lavker, Lei Cai, Wei Liu, Kegong Yang, Xiaodong He, Songsen Chen, 2010
  • The Tiny World of MicroRNAs in the Cross Hairs of the Mammalian Eye, Robert M. Lavker, Jia Yu, David G Ryan, 2009
  • MicroRNA-184 antagonizes microRNA-205 to maintain SHIP2 levels in epithelia, Jia Yu, David G. Ryan, Spiro Getsios, Michelle Oliveira-Fernandes, Anees Fatima, Robert M. Lavker, 2008
Rna Stem Cells Gene Expression Hematopoiesis Non-Coding Rna Epigenetics Cell Differentiation Translational Medicine Genomics Bioinformatics

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