Areas of Focus
- 3D genome structure regulation of cell fate
- Skeletal muscle adult stem cells, regeneration, aging, and degenerative diseases
- Molecular mechanisms of skeletal muscle and liver/fat 'dialogue' in chronic metabolic diseases
Academic Background & Achievements
- Achievement: Discovery of MyoD as a '3D genome organizer'
- Achievement: Concept of 'skeletal muscle metabolic microenvironment'
Publications
- Skeletal muscle-secreted DLPC orchestrates systemic energy homeostasis by enhancing adipose browning., Xiaodi Hu, Mingwei Sun, Qian Chen, Yixia Zhao, Na Liang, Siyuan Wang, Pengbin Yin, Yuanping Yang, Sin Man Lam, Qianying Zhang, Alimujiang Tudiyusufu, Yingying Gu, Xin Wan, Meihong Chen, Hu Li, Xiaofei Zhang, Guanghou Shui, Suneng Fu, Licheng Zhang, Peifu Tang, Catherine C.L. Wong, Yong Zhang, Dahai Zhu, 2023
- CTCF coordinates cell fate specification via orchestrating regulatory hubs with pioneer transcription factors., Yuting Liu, Xin Wan, Hu Li, Yingxi Chen, Xiaodi Hu, Hebing Chen, Dahai Zhu, Cheng Li, Yong Zhang, 2023
- The Aging Biomarker Consortium represents a new era for aging research in China., Aging Biomarker Consortium, 2023
- Biomarkers of aging., Aging Biomarker Consortium, 2023
- Global determination of reaction rates and lipid turnover kinetics in Mus musculus., Qishan Chen, Hu Li, He Tian, Sin Man Lam, Yilie Liao, Ziyin Zhang, Manyuan Dong, Shaoru Chen, Yuxiao Yao, Jiemiao Meng, Yong Zhang, Lemin Zheng, Zhuo-Xian Meng, Weiping Han, Guanghou Shui, Dahai Zhu, Suneng Fu, 2023
- MyoD is a 3D genome structure organizer for muscle cell identity., Ruiting Wang, Fengling Chen, Qian Chen, Xin Wan, Minglei Shi, Antony K. Chen, Zhao Ma, Guohong Li, Min Wang, Yachen Ying, Qinyao Liu, Hu Li, Xu Zhang, Jinbiao Ma, Jiayun Zhong, Meihong Chen, Michael Q. Zhang, Yong Zhang, Yang Chen, Dahai Zhu, 2022
- Muscle-secreted granulocyte colony-stimulating factor functions as metabolic niche factor ameliorating loss of muscle stem cells in aged mice., Hu Li, Qian Chen, Changyin Li, Ran Zhong, Yixia Zhao, Qianying Zhang, Weimin Tong, Dahai Zhu, Yong Zhang, 2019
- Linc-RAM is required for FGF2 function in regulating myogenic cell differentiation., Yixia Zhao, Fengqi Cao, Xiaohua Yu, Chuyan Chen, Jiao Meng, Ran Zhong, Yong Zhang, Dahai Zhu, 2018
- miR-127 enhances myogenic cell differentiation by targeting S1PR3., Lili Zhai, Rimao Wu, Wanhong Han, Yong Zhang, Dahai Zhu, 2017
- Long non-coding RNA Linc-RAM enhances myogenic differentiation by interacting with MyoD., Xiaohua Yu, Yong Zhang, Tingting Li, Zhao Ma, Haixue Jia, Qian Chen, Yixia Zhao, Lili Zhai, Ran Zhong, Changyin Li, Xiaoting Zou, Jiao Meng, Antony K. Chen, Pier Lorenzo Puri, Meihong Chen, Dahai Zhu, 2017
- miR-378 Activates the Pyruvate-PEP Futile Cycle and Enhances Lipolysis to Ameliorate Obesity in Mice., Yong Zhang, Changyin Li, Hu Li, Yipeng Song, Yixia Zhao, Lili Zhai, Haixia Wang, Ran Zhong, Huiru Tang, Dahai Zhu, 2016
- Acetoacetate accelerates muscle regeneration and ameliorates muscular dystrophy in mice., Xiaoting Zou, Jiao Meng, Li Li, Wanhong Han, Changyin Li, Ran Zhong, Xuexia Miao, Jun Cai, Yong Zhang, Dahai Zhu, 2016
- MicroRNA-431 accelerates muscle regeneration and ameliorates muscular dystrophy by targeting Pax7 in mice., Rimao Wu, Hu Li, Lili Zhai, Xiaoting Zou, Jiao Meng, Ran Zhong, Changyin Li, Haixia Wang, Yong Zhang, Dahai Zhu, 2015
- Myostatin induces mitochondrial metabolic alteration and typical apoptosis in cancer cells., Yong Liu, He Cheng, Yuchang Zhou, Yushan Zhu, Rui Bian, Yuewen Chen, Changyin Li, Qi Ma, Qiaoxia Zheng, Yong Zhang, Haijing Jin, Xiaohui Wang, Quan Chen, Dahai Zhu, 2013
- E3 ubiquitin ligase RNF13 involves spatial learning and assembly of the SNARE complex., Qiang Zhang, Yanfeng Li, Lei Zhang, Nan Yang, Jiao Meng, Pingping Zuo, Yong Zhang, Jie Chen, Li Wang, Xiang Gao, Dahai Zhu, 2013
