PhD: Chinese Academy of Medical Sciences, Institute of Materia Medica
Postdoctoral Research: Medical University of South Carolina, USA
Published multiple research papers in international journals with over 2600 citations
Postdoctoral Research - Medical University of South Carolina, USA - Tumor Therapy Research
Researcher - Chinese Academy of Medical Sciences, Institute of Basic Medical Sciences
Chinese Academy of Medical Sciences Peking Union Medical College Youth Innovation Award
Research
Tumor Immunology Biomechanics in Tumor Immunology Tumor Immunotherapy
Gasdermin E mediates resistance of pancreatic adenocarcinoma to enzymatic digestion through a YBX1–mucin pathway., Jiadi Lv, Yuying Liu, Siqi Mo, Yabo Zhou, Fengye Chen, Feiran Cheng, Cong Li, Dilizhatai Saimi, Mengyu Liu, Huafeng Zhang, Ke Tang, Jingwei Ma, Zhenfeng Wang, Qiangqiang Zhu, Wei-Min Tong & Bo Huang, 2022
IL-2 regulates tumor-reactive CD8+ T cell exhaustion by activating the aryl hydrocarbon receptor., Liu Y, Zhou N, Zhou L, Wang J, Zhou Y, Zhang T, Fang Y, Deng J, Gao Y, Liang X, Lv J, Wang Z, Xie J, Xue Y, Zhang H, Ma J, Tang K, Fang Y, Cheng F, Zhang C, Dong B, Zhao Y, Yuan P, Gao Q, Zhang H, Xiao-Feng Qin F, Huang B., 2021
Cell softness regulates tumorigenicity and stemness of cancer cells., Lv J, Liu Y, Cheng F, Li J, Zhou Y, Zhang T, Zhou N, Li C, Wang Z, Ma L, Liu M, Zhu Q, Liu X, Tang K, Ma J, Zhang H, Xie J, Fang Y, Zhang H, Wang N, Liu Y*, Huang B*, 2021
Cell softness prevents cytolytic T cell killing of tumor-repopulating cells., Liu Y*, Zhang T, Zhang H, Li J, Zhou N, Fiskesund R, Chen J, Lv J, Ma J, Zhang H, Tang K, Cheng F, Zhou Y, Zhang X, Wang N, Huang B*, 2021
ACE2 expression is regulated by AhR in SARS-CoV-2-infected macaques., Lv J, Yu P, Wang Z, Deng W, Bao L, Liu J, Li F, Zhu Q, Zhou N, Lv Q, Wang G, Wang S, Zhou Y, Song J, Tong WM, Liu Y*, Qin C*, Huang B*, 2021
Distinct uptake, amplification, and release of SARS-CoV-2 by M1 and M2 aleolar macrophages., Lv J, Wang Z, Qu Y, Zhu H, Zhu Q, Tong W, Bao L, Lv Q, Cong J, Li D, Deng W, Yu P, Song J, Tong WM, Liu J*, Liu Y*, Qin C*, Huang B*, 2021
Mucus production stimulated by IFN-AhR signaling triggers hypoxia of COVID-19., Liu Y, Lv J, Liu J, Li M, Xie J, Lv Q, Deng W, Zhou N, Zhou Y, Song J, Wang P, Qin C, Tong WM, Huang B, 2020
Methotrexate-loaded tumour-cell-derived microvesicles can relieve biliary obstruction in patients with extrahepatic cholangiocarcinoma., Gao Y, Zhang H, Zhou N, Xu P, Wang J, Gao Y, Jin X, Liang X, Lv J, Zhang Y, Tang K, Ma J, Zhang H, Xie J, Yao F, Tong W, Liu Y*, Wang X*, Huang B*, 2020
Gasdermin E-mediated target cell pyroptosis by CAR T cells triggers cytokine release syndrome., Liu Y, Fang Y, Chen X, Wang Z, Liang X, Zhang T, Liu M, Zhou N, Lv J, Tang K, Xie J, Gao Y, Cheng F, Zhou Y, Zhang Z, Hu Y, Zhang X, Gao Q, Zhang Y, Huang B, 2020
Visualization of perforin/gasdermin/complement-formed pores in real cell membranes using atomic force microscopy., Liu Y. et al., 2019
Tumor-Repopulating Cells Induce PD-1 Expression in CD8+ T Cells by Transferring Kynurenine and AhR Activation., Liu Y, Liang X, Dong W, Fang Y, Lv J, Zhang T, Fiskesund R, Xie J, Liu J, Yin X, Jin X, Chen D, Tang K, Ma J, Zhang H, Yu J, Yan J, Liang H, Mo S, Cheng F, Zhou Y, Zhang H, Wang J, Li J, Chen Y, Cui B, Hu ZW, Cao X, Xiao-Feng Qin F, Huang B, 2018
STAT3/p53 pathway activation disrupts IFN-beta-induced dormancy in tumor-repopulating cells., Liu Y, Lv J, Liu J, Liang X, Jin X, Xie J, Zhang L, Chen D, Fiskesund R, Tang K, Ma J, Zhang H, Dong W, Mo S, Zhang T, Cheng F, Zhou Y, Jia Q, Zhu B, Kong Y, Guo J, Zhang H, Hu ZW, Cao X, Qin FX, Huang B, 2018
Fibrin Stiffness Mediates Dormancy of Tumor-Repopulating Cells via a Cdc42-Driven Tet2 Epigenetic Program., Liu Y, Lv J, Liang X, Yin X, Zhang L, Chen D, Jin X, Fiskesund R, Tang K, Ma J, Zhang H, Dong W, Mo S, Zhang T, Cheng F, Zhou Y, Xie J, Wang N, Huang B, 2018
Blockade of IDO-kynurenine-AhR metabolic circuitry abrogates IFN-gamma-induced immunologic dormancy of tumor-repopulating cells., Liu Y, Liang X, Yin X, Lv J, Tang K, Ma J, Ji T, Zhang H, Dong W, Jin X, Chen D, Li Y, Zhang S, Xie HQ, Zhao B, Zhao T, Lu J, Hu ZW, Cao X, Qin FX, Huang B, 2017
