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Yuying Liu
Basic Medical Sciences
Peking Union Medical College
Beijing
Language: Chinese, English
Tumor
Immunology
Biomechanics
Therapy
Molecular Mechanisms
Immune Microenvironment
Cancer
Treatment
Research
Innovation
Areas of Focus
- Tumor Immunology
- Biomechanics in Tumor Immunology
- Tumor Immunotherapy
Work Experience
- Postdoctoral Research - Medical University of South Carolina, USA - Tumor Therapy Research
- Researcher - Chinese Academy of Medical Sciences, Institute of Basic Medical Sciences
Academic Background & Achievements
- PhD: Chinese Academy of Medical Sciences, Institute of Materia Medica
- Postdoctoral Research: Medical University of South Carolina, USA
- Published multiple research papers in international journals with over 2600 citations
Publications
- Gasdermin E mediates resistance of pancreatic adenocarcinoma to enzymatic digestion through a YBX1–mucin pathway., Jiadi Lv, Yuying Liu, Siqi Mo, Yabo Zhou, Fengye Chen, Feiran Cheng, Cong Li, Dilizhatai Saimi, Mengyu Liu, Huafeng Zhang, Ke Tang, Jingwei Ma, Zhenfeng Wang, Qiangqiang Zhu, Wei-Min Tong & Bo Huang, 2022
- IL-2 regulates tumor-reactive CD8+ T cell exhaustion by activating the aryl hydrocarbon receptor., Liu Y, Zhou N, Zhou L, Wang J, Zhou Y, Zhang T, Fang Y, Deng J, Gao Y, Liang X, Lv J, Wang Z, Xie J, Xue Y, Zhang H, Ma J, Tang K, Fang Y, Cheng F, Zhang C, Dong B, Zhao Y, Yuan P, Gao Q, Zhang H, Xiao-Feng Qin F, Huang B., 2021
- Cell softness regulates tumorigenicity and stemness of cancer cells., Lv J, Liu Y, Cheng F, Li J, Zhou Y, Zhang T, Zhou N, Li C, Wang Z, Ma L, Liu M, Zhu Q, Liu X, Tang K, Ma J, Zhang H, Xie J, Fang Y, Zhang H, Wang N, Liu Y*, Huang B*, 2021
- Cell softness prevents cytolytic T cell killing of tumor-repopulating cells., Liu Y*, Zhang T, Zhang H, Li J, Zhou N, Fiskesund R, Chen J, Lv J, Ma J, Zhang H, Tang K, Cheng F, Zhou Y, Zhang X, Wang N, Huang B*, 2021
- ACE2 expression is regulated by AhR in SARS-CoV-2-infected macaques., Lv J, Yu P, Wang Z, Deng W, Bao L, Liu J, Li F, Zhu Q, Zhou N, Lv Q, Wang G, Wang S, Zhou Y, Song J, Tong WM, Liu Y*, Qin C*, Huang B*, 2021
- Distinct uptake, amplification, and release of SARS-CoV-2 by M1 and M2 aleolar macrophages., Lv J, Wang Z, Qu Y, Zhu H, Zhu Q, Tong W, Bao L, Lv Q, Cong J, Li D, Deng W, Yu P, Song J, Tong WM, Liu J*, Liu Y*, Qin C*, Huang B*, 2021
- Mucus production stimulated by IFN-AhR signaling triggers hypoxia of COVID-19., Liu Y, Lv J, Liu J, Li M, Xie J, Lv Q, Deng W, Zhou N, Zhou Y, Song J, Wang P, Qin C, Tong WM, Huang B, 2020
- Methotrexate-loaded tumour-cell-derived microvesicles can relieve biliary obstruction in patients with extrahepatic cholangiocarcinoma., Gao Y, Zhang H, Zhou N, Xu P, Wang J, Gao Y, Jin X, Liang X, Lv J, Zhang Y, Tang K, Ma J, Zhang H, Xie J, Yao F, Tong W, Liu Y*, Wang X*, Huang B*, 2020
- Gasdermin E-mediated target cell pyroptosis by CAR T cells triggers cytokine release syndrome., Liu Y, Fang Y, Chen X, Wang Z, Liang X, Zhang T, Liu M, Zhou N, Lv J, Tang K, Xie J, Gao Y, Cheng F, Zhou Y, Zhang Z, Hu Y, Zhang X, Gao Q, Zhang Y, Huang B, 2020
- Visualization of perforin/gasdermin/complement-formed pores in real cell membranes using atomic force microscopy., Liu Y. et al., 2019
- Tumor-Repopulating Cells Induce PD-1 Expression in CD8+ T Cells by Transferring Kynurenine and AhR Activation., Liu Y, Liang X, Dong W, Fang Y, Lv J, Zhang T, Fiskesund R, Xie J, Liu J, Yin X, Jin X, Chen D, Tang K, Ma J, Zhang H, Yu J, Yan J, Liang H, Mo S, Cheng F, Zhou Y, Zhang H, Wang J, Li J, Chen Y, Cui B, Hu ZW, Cao X, Xiao-Feng Qin F, Huang B, 2018
- STAT3/p53 pathway activation disrupts IFN-beta-induced dormancy in tumor-repopulating cells., Liu Y, Lv J, Liu J, Liang X, Jin X, Xie J, Zhang L, Chen D, Fiskesund R, Tang K, Ma J, Zhang H, Dong W, Mo S, Zhang T, Cheng F, Zhou Y, Jia Q, Zhu B, Kong Y, Guo J, Zhang H, Hu ZW, Cao X, Qin FX, Huang B, 2018
- Fibrin Stiffness Mediates Dormancy of Tumor-Repopulating Cells via a Cdc42-Driven Tet2 Epigenetic Program., Liu Y, Lv J, Liang X, Yin X, Zhang L, Chen D, Jin X, Fiskesund R, Tang K, Ma J, Zhang H, Dong W, Mo S, Zhang T, Cheng F, Zhou Y, Xie J, Wang N, Huang B, 2018
- Blockade of IDO-kynurenine-AhR metabolic circuitry abrogates IFN-gamma-induced immunologic dormancy of tumor-repopulating cells., Liu Y, Liang X, Yin X, Lv J, Tang K, Ma J, Ji T, Zhang H, Dong W, Jin X, Chen D, Li Y, Zhang S, Xie HQ, Zhao B, Zhao T, Lu J, Hu ZW, Cao X, Qin FX, Huang B, 2017
Awards
- Chinese Academy of Medical Sciences Peking Union Medical College Youth Innovation Award
