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刘玉英
Basic Medical Sciences
北京协和医学院
北京
Language: 中文, 英语
肿瘤
免疫学
生物力学
治疗
分子机制
免疫微环境
癌症
研究
创新
Areas of Focus
- 肿瘤免疫学
- 生物力学在肿瘤免疫中的应用
- 肿瘤免疫治疗
Work Experience
- 博士后研究 - 美国南卡罗莱纳州医科大学 - 肿瘤治疗研究
- 研究员 - 中国医学科学院基础医学研究所
Academic Background & Achievements
- 博士：中国医学科学院药物研究所
- 博士后研究：美国南卡罗莱纳州医科大学
- 在国际期刊上发表多篇研究论文，被引用2600多次
Publications
- Gasdermin E mediates resistance of pancreatic adenocarcinoma to enzymatic digestion through a YBX1–mucin pathway., Jiadi Lv, Yuying Liu, Siqi Mo, Yabo Zhou, Fengye Chen, Feiran Cheng, Cong Li, Dilizhatai Saimi, Mengyu Liu, Huafeng Zhang, Ke Tang, Jingwei Ma, Zhenfeng Wang, Qiangqiang Zhu, Wei-Min Tong & Bo Huang, 2022
- IL-2 regulates tumor-reactive CD8+ T cell exhaustion by activating the aryl hydrocarbon receptor., Liu Y, Zhou N, Zhou L, Wang J, Zhou Y, Zhang T, Fang Y, Deng J, Gao Y, Liang X, Lv J, Wang Z, Xie J, Xue Y, Zhang H, Ma J, Tang K, Fang Y, Cheng F, Zhang C, Dong B, Zhao Y, Yuan P, Gao Q, Zhang H, Xiao-Feng Qin F, Huang B., 2021
- Cell softness regulates tumorigenicity and stemness of cancer cells., Lv J, Liu Y, Cheng F, Li J, Zhou Y, Zhang T, Zhou N, Li C, Wang Z, Ma L, Liu M, Zhu Q, Liu X, Tang K, Ma J, Zhang H, Xie J, Fang Y, Zhang H, Wang N, Liu Y*, Huang B*, 2021
- Cell softness prevents cytolytic T cell killing of tumor-repopulating cells., Liu Y*, Zhang T, Zhang H, Li J, Zhou N, Fiskesund R, Chen J, Lv J, Ma J, Zhang H, Tang K, Cheng F, Zhou Y, Zhang X, Wang N, Huang B*, 2021
- ACE2 expression is regulated by AhR in SARS-CoV-2-infected macaques., Lv J, Yu P, Wang Z, Deng W, Bao L, Liu J, Li F, Zhu Q, Zhou N, Lv Q, Wang G, Wang S, Zhou Y, Song J, Tong WM, Liu Y*, Qin C*, Huang B*, 2021
- Distinct uptake, amplification, and release of SARS-CoV-2 by M1 and M2 aleolar macrophages., Lv J, Wang Z, Qu Y, Zhu H, Zhu Q, Tong W, Bao L, Lv Q, Cong J, Li D, Deng W, Yu P, Song J, Tong WM, Liu J*, Liu Y*, Qin C*, Huang B*, 2021
- Mucus production stimulated by IFN-AhR signaling triggers hypoxia of COVID-19., Liu Y, Lv J, Liu J, Li M, Xie J, Lv Q, Deng W, Zhou N, Zhou Y, Song J, Wang P, Qin C, Tong WM, Huang B, 2020
- Methotrexate-loaded tumour-cell-derived microvesicles can relieve biliary obstruction in patients with extrahepatic cholangiocarcinoma., Gao Y, Zhang H, Zhou N, Xu P, Wang J, Gao Y, Jin X, Liang X, Lv J, Zhang Y, Tang K, Ma J, Zhang H, Xie J, Yao F, Tong W, Liu Y*, Wang X*, Huang B*, 2020
- Gasdermin E-mediated target cell pyroptosis by CAR T cells triggers cytokine release syndrome., Liu Y, Fang Y, Chen X, Wang Z, Liang X, Zhang T, Liu M, Zhou N, Lv J, Tang K, Xie J, Gao Y, Cheng F, Zhou Y, Zhang Z, Hu Y, Zhang X, Gao Q, Zhang Y, Huang B, 2020
- Visualization of perforin/gasdermin/complement-formed pores in real cell membranes using atomic force microscopy., Liu Y. et al., 2019
- Tumor-Repopulating Cells Induce PD-1 Expression in CD8+ T Cells by Transferring Kynurenine and AhR Activation., Liu Y, Liang X, Dong W, Fang Y, Lv J, Zhang T, Fiskesund R, Xie J, Liu J, Yin X, Jin X, Chen D, Tang K, Ma J, Zhang H, Yu J, Yan J, Liang H, Mo S, Cheng F, Zhou Y, Zhang H, Wang J, Li J, Chen Y, Cui B, Hu ZW, Cao X, Xiao-Feng Qin F, Huang B, 2018
- STAT3/p53 pathway activation disrupts IFN-beta-induced dormancy in tumor-repopulating cells., Liu Y, Lv J, Liu J, Liang X, Jin X, Xie J, Zhang L, Chen D, Fiskesund R, Tang K, Ma J, Zhang H, Dong W, Mo S, Zhang T, Cheng F, Zhou Y, Jia Q, Zhu B, Kong Y, Guo J, Zhang H, Hu ZW, Cao X, Qin FX, Huang B, 2018
- Fibrin Stiffness Mediates Dormancy of Tumor-Repopulating Cells via a Cdc42-Driven Tet2 Epigenetic Program., Liu Y, Lv J, Liang X, Yin X, Zhang L, Chen D, Jin X, Fiskesund R, Tang K, Ma J, Zhang H, Dong W, Mo S, Zhang T, Cheng F, Zhou Y, Xie J, Wang N, Huang B, 2018
- Blockade of IDO-kynurenine-AhR metabolic circuitry abrogates IFN-gamma-induced immunologic dormancy of tumor-repopulating cells., Liu Y, Liang X, Yin X, Lv J, Tang K, Ma J, Ji T, Zhang H, Dong W, Jin X, Chen D, Li Y, Zhang S, Xie HQ, Zhao B, Zhao T, Lu J, Hu ZW, Cao X, Qin FX, Huang B, 2017
Awards
- 中国医学科学院北京协和医学院科青年创新奖
