1990-1994: Bachelor's degree from Hunan Normal University
1994-1999: PhD in Biochemistry and Molecular Biology from Shanghai Institute of Biochemistry, Chinese Academy of Sciences
2001-2002: Master's degree in Computer Science from Yale University
Recipient of National 'Outstanding Youth Fund'
Recipient of CAS 'Hundred Talents Program'
Recipient of Peking Union Medical College 'Xiehe Scholar'
1999-2002: Research in Sidney Altman's lab at Yale University on RNA structure and function
2003-2004: Research in Amy Keating's lab at MIT on computational structural biology and systems biology
2004-2015: Researcher at the Institute of Biophysics, Chinese Academy of Sciences
2015-present: Researcher at the System Medicine Research Center, Chinese Academy of Medical Sciences and Suzhou Institute of Systems Medicine
National 'Outstanding Youth Fund'
CAS 'Hundred Talents Program'
Peking Union Medical College 'Xiehe Scholar'
Research
Development of new computational biology methods Molecular mechanisms of complex diseases Identification of key molecular markers for diseases
Continual Antigenic Diversification in China Leads to Global Antigenic Complexity of Avian Influenza H5N1 Viruses, Yousong Peng, Xiaodan Li, Hongbo Zhou, Aiping Wu, Libo Dong, Ye Zhang, Rongbao Gao, Hong Bo, Lei Yang, Dayan Wang, Xian Lin, Meilin Jin, Yuelong Shu, Taijiao Jiang, 2017
cooccurNet: an R package for co-occurrence network construction and analysis, Yuanqiang Zou, Zhiqiang Wu, Lizong Deng, Aiping Wu, Fan Wu, Kenli Li, Taijiao Jiang, Yousong Peng, 2017
A universal computational model for predicting antigenic variants of influenza A virus based on conserved antigenic structures, Yousong Peng, Dayan Wang, Jianhong Wang, Kenli Li, Zhongyang Tan, Yuelong Shu, Taijiao Jiang, 2017
Screening for Novel Small-Molecule Inhibitors Targeting the Assembly of Influenza Virus Polymerase Complex by a Bimolecular Luminescence Complementation-Based Reporter System, Chunfeng Li, Zining Wang, Yang Cao, Lulan Wang, Jingyun Jie, Zhigao Chen, Tao Deng, Taijiao Jiang, Genhong Cheng, F. Xiao-Feng Qin, 2017
PREDAC-H3: a user-friendly platform for antigenic surveillance of human influenza a (H3N2) virus based on hemagglutinin sequences, Yousong Peng, Lei Yang, Honglei Li, Yuanqiang Zou, Lizong Deng, Aiping Wu, Xiangjun Du, Dayan Wang, Yuelong Shu, Taijiao Jiang, 2016
From Mosquitos to Humans: Genetic Evolution of Zika Virus, Lulan Wang, Stephanie G. Valderramos, Aiping Wu, Songying Ouyang, Chunfeng Li, Patricia Brasil, Myrna Bonaldo, Thomas Coates, Karin Nielsen-Saines, Taijiao Jiang, Saba Aliyari, Genhong Cheng, 2016
Functional Genomics Reveals Linkers Critical for Influenza Polymerase, Lulan Wang, Aiping Wu, Yao E. Wang, Natalie Quanquin, Chunfeng Li, Jingfeng Wang, Hsiang-Wen Chen, Suyang Liu, Ping Liu, Hong Zhang, F. Xiao-Feng Qin, Taijiao Jiang, Genhong Cheng, 2016
Antigenic Patterns and Evolution of the Human Influenza A (H1N1) Virus, Mi Liu, Xiang Zhao, Sha Hua, Xiangjun Du, Yousong Peng, Xiyan Li, Yu Lan, Dayan Wang, Aiping Wu, Yuelong Shu, Taijiao Jiang, 2015
Network of co-mutations in Ebola virus genome predicts the disease lethality, Lizong Deng, Mi Liu, Sha Hua, Yousong Peng, Aiping Wu, F Xiao-Feng Qin, Genhong Cheng, Taijiao Jiang, 2015
Integrating computational modeling and functional assays to decipher the structure-function relationship of influenza virus PB1 protein, Chunfeng Li, Aiping Wu, Yousong Peng, Jingfeng Wang, Yang Guo, Zhigao Chen, Hong Zhang, Yongqiang Wang, Jiuhong Dong, Lulan Wang, F. Xiao-Feng Qin, Genhong Cheng, Tao Deng, Taijiao Jiang, 2014
Exploring protein domain organization by recognition of secondary structure packing interfaces, Lizong Deng, Aiping Wu, Wentao Dai, Tingrui Song, Ya Cui, Taijiao Jiang, 2014
Sequential Reassortments Underlie Diverse Influenza H7N9 Genotypes in China, Aiping Wu, Chunhu Su, Dayan Wang, Yousong Peng, Mi Liu, Sha Hua, Tianxian Li, George F. Gao, Hong Tang, Jianzhu Chen, Xiufan Liu, Yuelong Shu, Daxin Peng, Taijiao Jiang, 2013
A peptide derived from the C-terminus of PB1 inhibits influenza virus replication by interfering with viral polymerase assembly, Chunfeng Li, Qi Ba, Aiping Wu, Hong Zhang, Tao Deng, Taijiao Jiang, 2013
Mapping of H3N2 influenza antigenic evolution in China reveals a strategy for vaccine strain recommendation, Xiangjun Du, Libo Dong, Yu Lan, Yousong Peng, Aiping Wu, Ye Zhang, Weijuan Huang, Dayan Wang, Min Wang, Yuanji Guo, Yuelong Shu, Taijiao Jiang, 2012
RASP: Rapid modeling of protein side-chain conformations, Zhichao Miao, Yang Cao, Taijiao Jiang, 2011
NCACO-score: An effective main-chain dependent scoring function for structure modeling, Liqing Tian, Aiping Wu, Yang Cao, Xiaoxi Dong, Yun Hu, Taijiao Jiang, 2011
Improved side-chain modeling by coupling clash-detection guided iterative search with rotamer relaxation, Yang Cao, Lin Song, Zhichao Miao, Yun Hu, Liqing Tian, Taijiao Jiang, 2011
Synthetic circuits, devices and modules, Hong Zhang, Taijiao Jiang, 2010
Correlation of Influenza Virus Excess Mortality with Antigenic Variation: Application to Rapid Estimation of Influenza Mortality Burden, Aiping Wu, Yousong Peng, Xiangjun Du, Yuelong Shu, Taijiao Jiang, 2010
A computationally guided protein screen uncovers coiled-coil interactions involved in vesicular transport, Hong Zhang, Jinan Chen, Yongqiang Wang, Lin Peng, Xiaoxi Dong, Yi Lu, Amy E. Keating, Taijiao Jiang, 2009
Networks of genomic co-occurrence capture characteristics of human influenza A (H3N2) evolution, Xiangjun Du, Zhuo Wang, Aiping Wu, Lin Song, Yang Cao, Haiying Hang, Taijiao Jiang, 2008
Keywords
Protein Structure PredictionGene Co-Evolution AnalysisBiomedical Data MiningBiomolecular Network ModelingHigh-Throughput ExperimentsInfectious DiseasesMolecular MechanismsSystems BiologyDisease ClassificationEarly Diagnosis
Area of Focus
Environmental Factors | Cancer | Molecular Mechanisms | Signal Transduction | Gene Expression | Biomarkers | Drug Targets | Early Diagnosis | Prevention | Toxicology
