Professor | Zhi Zheng | Asia Growth Partners

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Name	Zhi Zheng
Contact Information	zhizheng100@126.com
Language ability	English, Chinese
Province	Beijing

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Name

Zhi Zheng

Contact Information

zhizheng100@126.com

Language ability

English, Chinese

Province

Beijing

University/Lab Affiliation and Title	Peking Union Medical College
Faculty	Basic Medical Sciences
Academic Background & Achievements	1988 - Bachelor's Degree in Chemistry: Peking University 1997 - PhD in Neuro Molecular Biology: Cornell University Postdoctoral Research: Stanford University School of Medicine, Hematology
Work Experience	1997-2000 - Stanford University School of Medicine - Postdoctoral Researcher 2000-2007 - Biotechnology Company in the USA - Gene Detection Technology Development 2007-present - Professor at Chinese Academy of Medical Sciences & Peking Union Medical College
Awards	Dean's Fellowship, Stanford University School of Medicine NIH Postdoctoral Fellowship (NRSA) 2007 - Clinical Chemistry Outstanding Scientific Contribution Award, AACC Northern California Section

University/Lab Affiliation and Title

Peking Union Medical College

Faculty

Basic Medical Sciences

Academic Background & Achievements

1988 - Bachelor's Degree in Chemistry: Peking University
1997 - PhD in Neuro Molecular Biology: Cornell University
Postdoctoral Research: Stanford University School of Medicine, Hematology

Work Experience

1997-2000 - Stanford University School of Medicine - Postdoctoral Researcher
2000-2007 - Biotechnology Company in the USA - Gene Detection Technology Development
2007-present - Professor at Chinese Academy of Medical Sciences & Peking Union Medical College

Awards

Dean's Fellowship, Stanford University School of Medicine
NIH Postdoctoral Fellowship (NRSA)
2007 - Clinical Chemistry Outstanding Scientific Contribution Award, AACC Northern California Section

Areas of Focus	Application of advanced biotechnology in clinical medicine and diagnostics Research on new technologies for large-scale, high-throughput, high-sensitivity rapid screening of infectious diseases Discovery and high-throughput detection of biomarkers for precision medicine and personalized medical clinical testing
Publications	A direct, sensitive and high-throughput genus- and species-specific molecular assay for large-scale malaria screening, Zhao YL, Zhao Y, Sun Y, Fan L, Wang D, Wang H, Sun X, Zheng Z, 2022 Photothermal Mediated Rolling Circle Amplification Toward Specific and Direct In Situ mRNA Detection, Liu D, Li W, Yang M, Qu L, Pian H, Huang Y, Cheng M, Zheng Z, 2021 GIPC2 is an endocrine-specific tumor suppressor gene for both sporadic and hereditary tumors of RET- and SDHB-, but not VHL-associated clusters of pheochromocytoma/paraganglioma, Dong, Y., Huang, Y., Fan, C. Wang L, Zhang R, Li W, Guo, Z; Wang D, Zheng, Z, 2021 Effectiveness of joint 3 + 1 malaria strategy along China–Myanmar cross border areas, Lin Z, Li S, Sun X, Zheng Z, Yang J, Pian H, Tian P, Chen Q, Sun X, Ding C, Duan K, Chen H, Bee DY, Zhou H, 2021 High-throughput, Multiplex Genotyping Directly from Blood or Dried Blood Spot without DNA Extraction for the Screening of Multiple G6PD Gene Variants at Risk for Drug-induced Hemolysis, Tian, X, Zhou, J, Zhao, Y., Cheng, Z., Song, W., Sun, Y., Sun, X., and Zheng, Z, 2017 Direct RNA detection without nucleic acid purification and PCR: Combining sandwich hybridization with signal amplification based on branched hybridization chain reaction, Xu Y and Zheng Z, 2016 Capture Ligation Probe-PCR (CLIP-PCR) for Molecular Screening, with Application to Active Malaria Surveillance for Elimination, Cheng Z, Wang D, Tian X, Sun Y, Sun X, Xiao N, Zheng Z, 2015 Quantitative survey of multiple CpGs from 5 genes identifies CpG methylation panel discriminating between high- and low-grade cervical intraepithelial neoplasia, Tian X, Chen D, Zhang R, Zhou J, Peng X, Yang X, Zhang X, Zheng Z, 2015 A paper-based skin patch for the diagnostic screening of cystic fibrosis, Mu X, Xin X, Fan C, Li X, Tian X, Xu K, Zheng Z, 2015 Multiplex Microfluidic Paper-based Immunoassay for the Diagnosis of Hepatitis C Virus Infection, Mu M, Zhang L, Chang S, Cui W and Zheng Z, 2014 Oil-water biphasic parallel flow for the precise patterning of metals and cells, Mu X, Liang Q, Zhou J, Ren K, Hu P, Wang Y, Zheng Z, Luo G, 2014 A Novel, Sensitive Assay for High-Throughput Molecular Detection of Plasmodia for Active Screening of Malaria for Elimination, Cheng, Z, Sun, X, Yang, Y, Wang, H and Zheng, Z, 2013 Determination of EGFR mutations in single cells microdissected from enriched lung tumor cells in peripheral blood, Ran R, Li L, Wang M, Wang S, Zheng Z, Lin PP, 2013 Sensitive and Quantitative Measurement of Gene Expression Directly from Small Amount of Whole Blood, Zheng, Z, Luo, Y., and McMaster, GK, 2006 蝎形探针扩增阻滞突变系统检测肺癌患者血清与肿瘤组织中表皮生长因子受体基因突变, 周南，李龙芸，郑直，李单青，崔巍，翁姗姗，王孟昭，王树兰，钟巍, 2011 晚期非小细胞肺癌患者使用EGFR-TKI治疗后长期生存的研究, 管慧,李龙芸,王孟昭,王树兰,韩如冰,钟巍,冉然,周京伟,郑直, 2011 抑癌基因甲基化位点定量检测在宫颈癌早期诊断中的意义探讨, 张秀茹;陈迪;田晓怡;郑直, 2012 无需逆转录的高通量多重呼吸道病毒RNA检测技术的建立, 杨丹丽，田晓怡，石伟先，郑直, 2013 基于金属增强荧光的高通量碱基突变的筛查, 徐瑶，郑直, 2014 同步原位检测CTC多重瘤标蛋白表达与染色体异倍体的意义, 由磊，赵烨，阚秀，李一林，王东民，张爱群，王红霞，刘颖，王丹丹，林平，郑直, 2017

Areas of Focus

Application of advanced biotechnology in clinical medicine and diagnostics
Research on new technologies for large-scale, high-throughput, high-sensitivity rapid screening of infectious diseases
Discovery and high-throughput detection of biomarkers for precision medicine and personalized medical clinical testing

Publications

A direct, sensitive and high-throughput genus- and species-specific molecular assay for large-scale malaria screening, Zhao YL, Zhao Y, Sun Y, Fan L, Wang D, Wang H, Sun X*, Zheng Z*, 2022
Photothermal Mediated Rolling Circle Amplification Toward Specific and Direct In Situ mRNA Detection, Liu D, Li W, Yang M, Qu L, Pian H, Huang Y, Cheng M, Zheng Z*, 2021
GIPC2 is an endocrine-specific tumor suppressor gene for both sporadic and hereditary tumors of RET- and SDHB-, but not VHL-associated clusters of pheochromocytoma/paraganglioma, Dong, Y., Huang, Y., Fan, C. Wang L, Zhang R, Li W, Guo, Z*; Wang D*, Zheng, Z*, 2021
Effectiveness of joint 3 + 1 malaria strategy along China–Myanmar cross border areas, Lin Z, Li S, Sun X*, Zheng Z*, Yang J, Pian H, Tian P, Chen Q, Sun X, Ding C, Duan K, Chen H, Bee DY, Zhou H*, 2021
High-throughput, Multiplex Genotyping Directly from Blood or Dried Blood Spot without DNA Extraction for the Screening of Multiple G6PD Gene Variants at Risk for Drug-induced Hemolysis, Tian, X, Zhou, J, Zhao, Y., Cheng, Z., Song, W., Sun, Y., Sun, X*., and Zheng, Z*, 2017
Direct RNA detection without nucleic acid purification and PCR: Combining sandwich hybridization with signal amplification based on branched hybridization chain reaction, Xu Y and Zheng Z*, 2016
Capture Ligation Probe-PCR (CLIP-PCR) for Molecular Screening, with Application to Active Malaria Surveillance for Elimination, Cheng Z, Wang D, Tian X, Sun Y, Sun X*, Xiao N*, Zheng Z*, 2015
Quantitative survey of multiple CpGs from 5 genes identifies CpG methylation panel discriminating between high- and low-grade cervical intraepithelial neoplasia, Tian X, Chen D, Zhang R, Zhou J, Peng X, Yang X*, Zhang X*, Zheng Z*, 2015
A paper-based skin patch for the diagnostic screening of cystic fibrosis, Mu X*, Xin X, Fan C, Li X, Tian X*, Xu K, Zheng Z*, 2015
Multiplex Microfluidic Paper-based Immunoassay for the Diagnosis of Hepatitis C Virus Infection, Mu M*, Zhang L, Chang S, Cui W and Zheng Z*, 2014
Oil-water biphasic parallel flow for the precise patterning of metals and cells, Mu X, Liang Q*, Zhou J, Ren K, Hu P, Wang Y, Zheng Z*, Luo G*, 2014
A Novel, Sensitive Assay for High-Throughput Molecular Detection of Plasmodia for Active Screening of Malaria for Elimination, Cheng, Z, Sun, X, Yang, Y, Wang, H and Zheng, Z*, 2013
Determination of EGFR mutations in single cells microdissected from enriched lung tumor cells in peripheral blood, Ran R, Li L*, Wang M, Wang S, Zheng Z*, Lin PP, 2013
Sensitive and Quantitative Measurement of Gene Expression Directly from Small Amount of Whole Blood, Zheng, Z*, Luo, Y., and McMaster, GK, 2006
蝎形探针扩增阻滞突变系统检测肺癌患者血清与肿瘤组织中表皮生长因子受体基因突变, 周南，李龙芸*，郑直*，李单青，崔巍，翁姗姗，王孟昭，王树兰，钟巍, 2011
晚期非小细胞肺癌患者使用EGFR-TKI治疗后长期生存的研究, 管慧,李龙芸*,王孟昭,王树兰,韩如冰,钟巍,冉然,周京伟,郑直*, 2011
抑癌基因甲基化位点定量检测在宫颈癌早期诊断中的意义探讨, 张秀茹;陈迪;田晓怡;郑直*, 2012
无需逆转录的高通量多重呼吸道病毒RNA检测技术的建立, 杨丹丽，田晓怡，石伟先，郑直*, 2013
基于金属增强荧光的高通量碱基突变的筛查, 徐瑶，郑直*, 2014
同步原位检测CTC多重瘤标蛋白表达与染色体异倍体的意义, 由磊，赵烨，阚秀，李一林，王东民，张爱群，王红霞，刘颖，王丹丹，林平，郑直*, 2017

Biotechnology Clinical Medicine Diagnostics Infectious Diseases High-Throughput Sensitivity Screening Biomarkers Precision Medicine Personalized Medicine

Lemin Zheng - Peking University

Bo Tian - Central South University

Liu Yun - Fudan University

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