Professor | Yunyu Shi | Asia Growth Partners

Name	Yunyu Shi
Contact Information	yyshi@ustc.edu.cn
Language ability	Chinese, English
Province	Anhui

Name

Yunyu Shi

Contact Information

yyshi@ustc.edu.cn

Language ability

Chinese, English

Province

Anhui

University/Lab Affiliation and Title	University of Science and Technology of China
Faculty	Life Sciences
Academic Background & Achievements	1960-1965: Studied at University of Science and Technology of China, graduated in Biophysics 1997: Elected as Academician of the Chinese Academy of Sciences 2009: Elected as Academician of the Academy of Sciences for the Developing World
Work Experience	1965-1970: Intern Researcher at Ministry of Health, Institute of Traditional Chinese Medicine 1970-present: University of Science and Technology of China, roles from Assistant to Professor 1998-2002: Dean of the School of Life Sciences, University of Science and Technology of China 2002-2012: Chair of the Teaching Steering Committee for Biology and Bioengineering, Ministry of Education
Awards	1994: Awarded 'Outstanding Young and Middle-aged Expert with Outstanding Contributions' by the Chinese Academy of Sciences 2007: Awarded the Third National Higher Education Teaching Master Award by the Ministry of Education 2021: Awarded the Bei Shizhang Outstanding Contribution Award by the Chinese Biophysical Society

University/Lab Affiliation and Title

University of Science and Technology of China

Faculty

Life Sciences

Academic Background & Achievements

1960-1965: Studied at University of Science and Technology of China, graduated in Biophysics
1997: Elected as Academician of the Chinese Academy of Sciences
2009: Elected as Academician of the Academy of Sciences for the Developing World

Work Experience

1965-1970: Intern Researcher at Ministry of Health, Institute of Traditional Chinese Medicine
1970-present: University of Science and Technology of China, roles from Assistant to Professor
1998-2002: Dean of the School of Life Sciences, University of Science and Technology of China
2002-2012: Chair of the Teaching Steering Committee for Biology and Bioengineering, Ministry of Education

Awards

1994: Awarded 'Outstanding Young and Middle-aged Expert with Outstanding Contributions' by the Chinese Academy of Sciences
2007: Awarded the Third National Higher Education Teaching Master Award by the Ministry of Education
2021: Awarded the Bei Shizhang Outstanding Contribution Award by the Chinese Biophysical Society

Areas of Focus	Structural biology and molecular cellular mechanisms of aging and degenerative diseases Epigenetic regulation of mitochondrial genome and degenerative diseases Membrane-less organelles, biomolecular condensates, and phase separation in cells
Publications	Structural insights into the specific recognition of mitochondrial ribosome-binding factor hsRBFA and 12 S rRNA by methyltransferase METTL15, MQ Lv, WW Zhou, YJ Hao, FD Li, HF Zhang H, XB Yao, YY Shi, L Zhang, 2024 Phase separation of hnRNPA1 and TERRA regulates telomeric stability, ZY Xu, YR Liu Y, FD Li, Y Yang, H Zhang, X Liu, X Xie, XJ Chen, YY Shi, L Zhang, 2024 Structural insights into dimethylation of 12S rRNA by TFB1M: indispensable role in translation of mitochondrial genes and mitochondrial function, X.D. Liu, S.Q. Shen, P.Z. Wu. F.D. Li, X. Liu, C. Y. Wang, Q.G. Gong, J.H. Wu, X.B. Yao, H. F Zhang,* and Y. Y. Shi, 2019 Application of NMR Spectroscopy to Determine Small RNA Structure, P.Z. Wu, X. Liu, G.G. Gong, Y.Y. Shi, J.H. Wu, 2020 A conserved dimer interface connects ERH and YTH family proteins to promote gene silencing, G.D. Xie, TV. Vo, G. Thillainadesan, S. Holla, B. Zhang, Y. Jiang, M.Q. Lv, Z. Xu, C.Y. Wang, V. Balachandran, Y.Y. Shi Y, F.D Li, S. Grewal, 2019 TRIM66 Reads Unmodified H3R2K4 and H3K56ac to Respond to DNA Damage in Embryonic Stem Cells, J.J. Chen, Z. Wang, X. Guo, F.D. Li, Q.T. Wei, X. Chen, D.S. Gong , Y. Xu, W. Chen, Y. Liu, J. H. Kang, Y.Y. Shi, 2019 Structural Insights Into ceNAP1 Chaperoning Activity Toward ceH2A-H2B, Y. Liu, L.Xu, C. Xie, J. Hong, FD Li, K. Ruan K, JJ. Chen, JH Wu, YY Shi*, 2019

Areas of Focus

Structural biology and molecular cellular mechanisms of aging and degenerative diseases
Epigenetic regulation of mitochondrial genome and degenerative diseases
Membrane-less organelles, biomolecular condensates, and phase separation in cells

Publications

Structural insights into the specific recognition of mitochondrial ribosome-binding factor hsRBFA and 12 S rRNA by methyltransferase METTL15, MQ Lv, WW Zhou, YJ Hao, FD Li, HF Zhang H, XB Yao, YY Shi*, L Zhang*, 2024
Phase separation of hnRNPA1 and TERRA regulates telomeric stability, ZY Xu, YR Liu Y, FD Li, Y Yang, H Zhang, X Liu, X Xie, XJ Chen, YY Shi*, L Zhang*, 2024
Structural insights into dimethylation of 12S rRNA by TFB1M: indispensable role in translation of mitochondrial genes and mitochondrial function, X.D. Liu, S.Q. Shen, P.Z. Wu. F.D. Li, X. Liu, C. Y. Wang, Q.G. Gong, J.H. Wu, X.B. Yao, H. F Zhang,* and Y. Y. Shi*, 2019
Application of NMR Spectroscopy to Determine Small RNA Structure, P.Z. Wu, X. Liu, G.G. Gong, Y.Y. Shi, J.H. Wu, 2020
A conserved dimer interface connects ERH and YTH family proteins to promote gene silencing, G.D. Xie, TV. Vo, G. Thillainadesan, S. Holla, B. Zhang, Y. Jiang, M.Q. Lv, Z. Xu, C.Y. Wang, V. Balachandran, Y.Y. Shi Y, F.D Li*, S. Grewal*, 2019
TRIM66 Reads Unmodified H3R2K4 and H3K56ac to Respond to DNA Damage in Embryonic Stem Cells, J.J. Chen, Z. Wang, X. Guo, F.D. Li, Q.T. Wei, X. Chen, D.S. Gong , Y. Xu, W. Chen, Y. Liu, J. H. Kang*, Y.Y. Shi*, 2019
Structural Insights Into ceNAP1 Chaperoning Activity Toward ceH2A-H2B, Y. Liu, L.Xu, C. Xie, J. Hong, FD Li, K. Ruan K, JJ. Chen, JH Wu*, YY Shi*, 2019

Aging Degenerative Diseases Structural Biology Molecular Mechanisms Epigenetics Mitochondrial Genome Neurodegenerative Diseases Biophysics Biochemistry Cell Biology

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