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Yunyu Shi
yyshi@ustc.edu.cn
Chinese, English
Anhui
University of Science and Technology of China
Life Sciences
  • 1960-1965: Studied at University of Science and Technology of China, graduated in Biophysics
  • 1997: Elected as Academician of the Chinese Academy of Sciences
  • 2009: Elected as Academician of the Academy of Sciences for the Developing World
  • 1965-1970: Intern Researcher at the Ministry of Health's Institute of Traditional Chinese Medicine
  • 1970-present: Assistant, Lecturer, Associate Professor, Professor at University of Science and Technology of China
  • 1998-2002: First Dean of the School of Life Sciences, University of Science and Technology of China
  • 2002-2012: Chairman of the Teaching Steering Committee for Biology and Bioengineering, Ministry of Education
  • 1994: Award for Outstanding Young and Middle-aged Experts with Contributions by the Chinese Academy of Sciences
  • 2007: Third National Teaching Master Award by the Ministry of Education
  • 2021: Bei Shizhang Outstanding Contribution Award by the Biophysical Society of China
Structural biology and molecular cellular mechanisms of aging and degenerative diseases
Epigenetic regulation of mitochondrial genome and degenerative diseases
Membrane-less organelles, biomolecular condensates, biological phase separation and phase transition mechanisms
  • Structural insights into the specific recognition of mitochondrial ribosome-binding factor hsRBFA and 12 S rRNA by methyltransferase METTL15, MQ Lv, WW Zhou, YJ Hao, FD Li, HF Zhang H, XB Yao, YY Shi*, L Zhang*, 2024
  • Phase separation of hnRNPA1 and TERRA regulates telomeric stability, ZY Xu, YR Liu Y, FD Li, Y Yang, H Zhang, X Liu, X Xie, XJ Chen, YY Shi*, L Zhang*, 2024
  • Structural insights into dimethylation of 12S rRNA by TFB1M: indispensable role in translation of mitochondrial genes and mitochondrial function, X.D. Liu, S.Q. Shen, P.Z. Wu. F.D. Li, X. Liu, C. Y. Wang, Q.G. Gong, J.H. Wu, X.B. Yao, H. F Zhang,* and Y. Y. Shi*, 2019
  • Application of NMR Spectroscopy to Determine Small RNA Structure, P.Z. Wu, X. Liu, G.G. Gong, Y.Y. Shi, J.H. Wu, 2020
  • A conserved dimer interface connects ERH and YTH family proteins to promote gene silencing, G.D. Xie, TV. Vo, G. Thillainadesan, S. Holla, B. Zhang, Y. Jiang, M.Q. Lv, Z. Xu, C.Y. Wang, V. Balachandran, Y.Y. Shi Y, F.D Li*, S. Grewal*, 2019
  • TRIM66 Reads Unmodified H3R2K4 and H3K56ac to Respond to DNA Damage in Embryonic Stem Cells, J.J. Chen, Z. Wang, X. Guo, F.D. Li, Q.T. Wei, X. Chen, D.S. Gong , Y. Xu, W. Chen, Y. Liu, J. H. Kang*, Y.Y. Shi*, 2019
  • Structural Insights Into ceNAP1 Chaperoning Activity Toward ceH2A-H2B, Y. Liu, L.Xu, C. Xie, J. Hong, FD Li, K. Ruan K, JJ. Chen, JH Wu*, YY Shi*, 2019
Aging Degenerative Diseases Structural Biology Molecular Mechanisms Epigenetic Regulation Mitochondrial Genome Neurodegenerative Diseases Biophysics Biochemistry Cell Biology

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