Professor | Wang Chao | Asia Growth Partners

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Name	Wang Chao
Contact Information	cwangust@ustc.edu.cn
Language ability	Chinese, English
Province	Anhui

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Name

Wang Chao

Contact Information

cwangust@ustc.edu.cn

Language ability

Chinese, English

Province

Anhui

University/Lab Affiliation and Title	University of Science and Technology of China
Faculty	Life Sciences
Academic Background & Achievements	2005/09-2009/06 Bachelor: Shanghai Jiao Tong University, Bioengineering 2009/08-2014/06 PhD: Hong Kong University of Science and Technology, Biochemistry 2013/04-2013/07 Visiting Scholar: Duke University School of Medicine National Science Foundation 'Outstanding Youth Science Fund' recipient (2021) Chinese Academy of Sciences 'Pioneer Initiative' participant (2016)
Work Experience	2014/07-2016/02 Postdoctoral Researcher: Hong Kong University of Science and Technology 2016/03-Present Researcher/Professor: University of Science and Technology of China, School of Life Sciences
Awards	USTC 'Academic Leading Talent Training Program' (2021) USTC 'Zhai Guanglong Scholar Fund' (2021) Life Sciences and Medicine Division Academic Career Development Award (2020) Ministry of Education Key Laboratory of Cell Dynamics Outstanding Research Award (2020)

University/Lab Affiliation and Title

University of Science and Technology of China

Faculty

Life Sciences

Academic Background & Achievements

2005/09-2009/06 Bachelor: Shanghai Jiao Tong University, Bioengineering
2009/08-2014/06 PhD: Hong Kong University of Science and Technology, Biochemistry
2013/04-2013/07 Visiting Scholar: Duke University School of Medicine
National Science Foundation 'Outstanding Youth Science Fund' recipient (2021)
Chinese Academy of Sciences 'Pioneer Initiative' participant (2016)

Work Experience

2014/07-2016/02 Postdoctoral Researcher: Hong Kong University of Science and Technology
2016/03-Present Researcher/Professor: University of Science and Technology of China, School of Life Sciences

Awards

USTC 'Academic Leading Talent Training Program' (2021)
USTC 'Zhai Guanglong Scholar Fund' (2021)
Life Sciences and Medicine Division Academic Career Development Award (2020)
Ministry of Education Key Laboratory of Cell Dynamics Outstanding Research Award (2020)

Areas of Focus	Neuronal cell polarity maintenance and chemical intervention
Publications	Dynamic interactions between E-cadherin and Ankyrin-G mediate epithelial cell polarity maintenance., Kong C, Qu X, Liu M, Xu W, Chen D, Zhang Y, Zhang S, Zhu F, Liu Z, Li J, Huang C, and Wang C., 2023 Crystal structure of Ankyrin-G in complex with a fragment of Neurofascin reveals binding mechanisms required for integrity of the axon initial segment., He L, Jiang W, Li J, and Wang C., 2022 Promotion of row 1–specific tip complex condensates by Gpsm2-Gαi provides insights into row identity of the tallest stereocilia., Shi Y#, Lin L#, Wang C, and Zhu J., 2022 5-IP7 is a GPCR messenger mediating neural control of synaptotagmin-dependent insulin exocytosis and glucose homeostasis., Zhang X#, Li N#, Zhang J#, Zhang Y#, Yang X#, Luo Y, Zhang B, Xu Z, Zhu Z, Yang X, Yan Y, Lin B, Wang S, Chen D, Ye C, Ding Y, Lou M, Wu Q, Hou Z, Zhang K, Liang Z, Wei A, Wang B, Wang C, Jiang N, Zhang W, Xiao G, Ma C, Ren Y, Qi X, Han W, Wang C, and Rao F., 2021 Structural basis of GABARAP-mediated GABAA receptor trafficking and functions on GABAergic synaptic transmission., Ye J#, Zou G#, Zhu R, Kong C, Miao C, Zhang M, Li J, Xiong W, and Wang C., 2021 Double inhibition and activation mechanisms of Ephexin family RhoGEFs., Zhang M#, Lin L#, Wang C, and Zhu J., 2021 Mechanistic insights into the interactions of dynein regulator Ndel1 with neuronal ankyrins and implications in polarity maintenance., Ye J#, Li J#, Ye F, Zhang Y, Zhang M, and Wang C., 2020 Potent and specific Atg8-targeting autophagy inhibitory peptides from giant ankyrins., Li J#, Zhu R#, Chen K, Zheng H, Zhao H, Yuan C, Zhang H, Wang C, and Zhang M*., 2018

Areas of Focus

Neuronal cell polarity maintenance and chemical intervention

Publications

Dynamic interactions between E-cadherin and Ankyrin-G mediate epithelial cell polarity maintenance., Kong C, Qu X, Liu M, Xu W, Chen D, Zhang Y, Zhang S, Zhu F, Liu Z, Li J, Huang C*, and Wang C*., 2023
Crystal structure of Ankyrin-G in complex with a fragment of Neurofascin reveals binding mechanisms required for integrity of the axon initial segment., He L, Jiang W, Li J*, and Wang C*., 2022
Promotion of row 1–specific tip complex condensates by Gpsm2-Gαi provides insights into row identity of the tallest stereocilia., Shi Y#, Lin L#, Wang C*, and Zhu J*., 2022
5-IP7 is a GPCR messenger mediating neural control of synaptotagmin-dependent insulin exocytosis and glucose homeostasis., Zhang X#, Li N#, Zhang J#, Zhang Y#, Yang X#, Luo Y, Zhang B, Xu Z, Zhu Z, Yang X, Yan Y, Lin B, Wang S, Chen D, Ye C, Ding Y, Lou M, Wu Q, Hou Z, Zhang K, Liang Z, Wei A, Wang B, Wang C, Jiang N, Zhang W, Xiao G, Ma C, Ren Y, Qi X, Han W, Wang C*, and Rao F*., 2021
Structural basis of GABARAP-mediated GABAA receptor trafficking and functions on GABAergic synaptic transmission., Ye J#, Zou G#, Zhu R, Kong C, Miao C, Zhang M, Li J*, Xiong W*, and Wang C*., 2021
Double inhibition and activation mechanisms of Ephexin family RhoGEFs., Zhang M#, Lin L#, Wang C*, and Zhu J*., 2021
Mechanistic insights into the interactions of dynein regulator Ndel1 with neuronal ankyrins and implications in polarity maintenance., Ye J#, Li J#, Ye F, Zhang Y, Zhang M, and Wang C*., 2020
Potent and specific Atg8-targeting autophagy inhibitory peptides from giant ankyrins., Li J#, Zhu R#, Chen K, Zheng H, Zhao H, Yuan C, Zhang H*, Wang C*, and Zhang M*., 2018

Neuronal Cell Polarity Chemical Intervention Scaffold Proteins Protein Complexes Structural Biology Chemical Biology Molecular Mechanisms Neural Network Regulation Disease Pathogenesis Drug Development

Sarah Perrett - University of Chinese Academy of Sciences

Haiping Liu - University of Chinese Academy of Sciences

Boxun Lu - Fudan University

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