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Jihui Wu
Life Science
University of Science and Technology of China
Anhui
Language: Chinese, English
Nmr
Proteins
Nucleic Acids
Spectroscopy
Structure Determination
Function Relationship
Protein Interactions
Structural Genomics
High-Throughput
Metabolomics
Areas of Focus
- NMR studies of proteins and nucleic acids
- Biological NMR spectroscopy methodology
- Protein structure determination and structure-function relationship
- Protein-protein, protein-nucleic acid, and protein-ligand interactions
- Structural genomics for high-throughput structure determination
- NMR methodology in metabolomics
Work Experience
- Post-1988 - Teaching and research in NMR and structural biology at the School of Life Sciences, University of Science and Technology of China
- 1995 - Advanced study in NMR experimental techniques and protein structure modification methods at the Institute of Molecular Biology and Biophysics, ETH Zurich
Academic Background & Achievements
- 1982 - Bachelor's Degree in Cell Biology: University of Science and Technology of China
- 1988 - Master's Degree in Science: Institute of Biophysics, Chinese Academy of Sciences
Publications
- Conformational change upon ligand binding and dynamics of the PDZ domain from leukemia-associated Rho guanine nucleotide exchange factor, Jiangxin Liu, Jiahai Zhang, Yinshan Yang, Hongda Huang, Weiqun Shen, Qi Hu, Xingsheng Wang, Jihui Wu, and Yunyu Shi, 2008
- Interesting Structural and Dynamical Behaviors Exhibited by the AF-6 PDZ Domain upon Bcr Peptide Binding, Xiaogang Niu, Quan Chen, Jiahai Zhang, Weiqun Shen, Yunyu Shi, and Jihui Wu, 2007
- Investigation of the Structural Stability of hUBF HMG Box 5 by Native-State Hydrogen Exchange, Dandan Wang, Jiahai Zhang, Xianju Jin, Jihui Wu, and Yunyu Shi, 2007
- Solution structure of GOPC PDZ domain and its interaction with the C-terminal motif of neuroligin, Li, X., Zhang, J. H., Cao, Z. X., Wu, J. H. and Shi, Y. Y., 2006
- Solution structure of AF-6 PDZ domain and its interaction with the C-terminal peptides from neurexin and Bcr, Heyue Zhou, Yingqi Xu, Anding Huang, Jihui Wu, Yunyu Shi, 2005
- General Method for Suppression of Diagonal Peaks in Heteronuclear-Edited NOESY Spectroscopy, Jihui Wu, Jing-song Fan, Steven M. Pascal, and Daiwen Yang, 2004
