Professor | Hua Feng Zhang | Asia Growth Partners

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Name	Hua Feng Zhang
Contact Information	hzhang22@ustc.edu.cn
Language ability	Chinese, English
Province	Anhui

Upload Avatar (500 x 500)

Name

Hua Feng Zhang

Contact Information

hzhang22@ustc.edu.cn

Language ability

Chinese, English

Province

Anhui

University/Lab Affiliation and Title	University of Science and Technology of China
Faculty	Basic Medical Sciences
Awards	National Science Fund for Distinguished Young Scholars

University/Lab Affiliation and Title

University of Science and Technology of China

Faculty

Basic Medical Sciences

Awards

National Science Fund for Distinguished Young Scholars

Areas of Focus	Tumor microenvironment and tumor metabolism Molecular mechanisms of tumor metastasis Epigenetics and tumor development Screening and development of novel anti-tumor drugs
Publications	Secreted protease PRSS35 suppresses hepatocellular carcinoma by disabling CXCL2-mediated neutrophil extracellular traps., Wang T, Zhou Y, Zhou Z, Zhang P, Yan R, Sun L, Ma W, Zhang T, Shen S, Liu H, Lu H, Ye L, Feng J, Chen Z, Zhong X, Wu G, Cai Y, Jia W, Gao P, Zhang H., 2023 Genome-wide CRISPR screen identifies synthetic lethality between DOCK1 inhibition and metformin in liver cancer., Feng J, Lu H, Ma W, Tian W, Lu Z, Yang H, Cai Y, Cai P, Sun Y, Zhou Z, Feng J, Deng J, Shu Y, Qu K, Jia W, Gao P, Zhang H., 2022 ENO1 suppresses cancer cell ferroptosis by degrading the mRNA of iron regulatory protein 1., Zhang T, Sun L, Hao Y, Suo C, Shen S, Wei H, Ma W, Zhang P, Wang T, Gu X, Li S, Chen Z, Yan R, Zhang Y, Cai Y, Zhou R, Jia W, Huang F, Gao P, Zhang H., 2022 Hypoxia-induced suppression of alternative splicing of MBD2 promotes breast cancer metastasis via activation of FZD1., Liu Z, Sun L, Cai Y, Shen S, Zhang T, Wang N, Wu G, Ma W, Li ST, Suo C, Hao Y, Jia WD, Semenza GL, Gao P, Zhang H., 2021 Myc-mediated SDHA acetylation triggers epigenetic regulation of gene expression and tumorigenesis., Li ST, Huang D, Shen S, Cai Y, Xing S, Wu G, Jiang Z, Hao Y, Yuan M, Wang N, Zhu L, Yan R, Yang D, Wang L, Liu Z, Hu X, Zhou R, Qu K, Li A, Duan X, Zhang H, Gao P., 2020 DIS3L2 promotes progression of hepatocellular carcinoma via hnRNPU-mediated alternative splicing., Xing S, Li Z, Ma W, He X, Shen S, Wei H, Li ST, Shu Y, Sun L, Zhong X, Huangfu Y, Su L, Feng J, Zhang X, Gao P, Jia WD, Zhang H., 2019 Hepatocellular carcinoma redirects to ketolysis for progression under nutrition stress., Huang D, Li T, Wang L, Zhang L, Yan R, Kui Li, Xing S, Wu G, Hu L, Jia W, Lin S, Dang CV, Song L, Gao P, Zhang H., 2016

Areas of Focus

Tumor microenvironment and tumor metabolism
Molecular mechanisms of tumor metastasis
Epigenetics and tumor development
Screening and development of novel anti-tumor drugs

Publications

Secreted protease PRSS35 suppresses hepatocellular carcinoma by disabling CXCL2-mediated neutrophil extracellular traps., Wang T, Zhou Y, Zhou Z, Zhang P, Yan R, Sun L, Ma W, Zhang T, Shen S, Liu H, Lu H, Ye L, Feng J, Chen Z, Zhong X, Wu G, Cai Y, Jia W, Gao P, Zhang H., 2023
Genome-wide CRISPR screen identifies synthetic lethality between DOCK1 inhibition and metformin in liver cancer., Feng J, Lu H, Ma W, Tian W, Lu Z, Yang H, Cai Y, Cai P, Sun Y, Zhou Z, Feng J, Deng J, Shu Y, Qu K, Jia W, Gao P, Zhang H., 2022
ENO1 suppresses cancer cell ferroptosis by degrading the mRNA of iron regulatory protein 1., Zhang T, Sun L, Hao Y, Suo C, Shen S, Wei H, Ma W, Zhang P, Wang T, Gu X, Li S, Chen Z, Yan R, Zhang Y, Cai Y, Zhou R, Jia W, Huang F, Gao P, Zhang H., 2022
Hypoxia-induced suppression of alternative splicing of MBD2 promotes breast cancer metastasis via activation of FZD1., Liu Z, Sun L, Cai Y, Shen S, Zhang T, Wang N, Wu G, Ma W, Li ST, Suo C, Hao Y, Jia WD, Semenza GL, Gao P, Zhang H., 2021
Myc-mediated SDHA acetylation triggers epigenetic regulation of gene expression and tumorigenesis., Li ST, Huang D, Shen S, Cai Y, Xing S, Wu G, Jiang Z, Hao Y, Yuan M, Wang N, Zhu L, Yan R, Yang D, Wang L, Liu Z, Hu X, Zhou R, Qu K, Li A, Duan X, Zhang H, Gao P., 2020
DIS3L2 promotes progression of hepatocellular carcinoma via hnRNPU-mediated alternative splicing., Xing S, Li Z, Ma W, He X, Shen S, Wei H, Li ST, Shu Y, Sun L, Zhong X, Huangfu Y, Su L, Feng J, Zhang X, Gao P, Jia WD, Zhang H., 2019
Hepatocellular carcinoma redirects to ketolysis for progression under nutrition stress., Huang D, Li T, Wang L, Zhang L, Yan R, Kui Li, Xing S, Wu G, Hu L, Jia W, Lin S, Dang CV, Song L, Gao P, Zhang H., 2016

Tumor Microenvironment Metabolism Metastasis Molecular Mechanisms Epigenetics Development Anti-Tumor Drugs

Lin He - Peking University

Zhiyao Hou - Guangzhou Medical University

Qi Tang - Nanjing Medical University

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