Areas of Focus
- Tumor microenvironment and tumor metabolism
- Molecular mechanisms of tumor metastasis
- Epigenetics and tumor development
- Screening and development of novel anti-tumor drugs
Publications
- Secreted protease PRSS35 suppresses hepatocellular carcinoma by disabling CXCL2-mediated neutrophil extracellular traps., Wang T, Zhou Y, Zhou Z, Zhang P, Yan R, Sun L, Ma W, Zhang T, Shen S, Liu H, Lu H, Ye L, Feng J, Chen Z, Zhong X, Wu G, Cai Y, Jia W, Gao P, Zhang H., 2023
- Genome-wide CRISPR screen identifies synthetic lethality between DOCK1 inhibition and metformin in liver cancer., Feng J, Lu H, Ma W, Tian W, Lu Z, Yang H, Cai Y, Cai P, Sun Y, Zhou Z, Feng J, Deng J, Shu Y, Qu K, Jia W, Gao P, Zhang H., 2022
- ENO1 suppresses cancer cell ferroptosis by degrading the mRNA of iron regulatory protein 1., Zhang T, Sun L, Hao Y, Suo C, Shen S, Wei H, Ma W, Zhang P, Wang T, Gu X, Li S, Chen Z, Yan R, Zhang Y, Cai Y, Zhou R, Jia W, Huang F, Gao P, Zhang H., 2022
- Hypoxia-induced suppression of alternative splicing of MBD2 promotes breast cancer metastasis via activation of FZD1., Liu Z, Sun L, Cai Y, Shen S, Zhang T, Wang N, Wu G, Ma W, Li ST, Suo C, Hao Y, Jia WD, Semenza GL, Gao P, Zhang H., 2021
- Myc-mediated SDHA acetylation triggers epigenetic regulation of gene expression and tumorigenesis., Li ST, Huang D, Shen S, Cai Y, Xing S, Wu G, Jiang Z, Hao Y, Yuan M, Wang N, Zhu L, Yan R, Yang D, Wang L, Liu Z, Hu X, Zhou R, Qu K, Li A, Duan X, Zhang H, Gao P., 2020
- DIS3L2 promotes progression of hepatocellular carcinoma via hnRNPU-mediated alternative splicing., Xing S, Li Z, Ma W, He X, Shen S, Wei H, Li ST, Shu Y, Sun L, Zhong X, Huangfu Y, Su L, Feng J, Zhang X, Gao P, Jia WD, Zhang H., 2019
- Hepatocellular carcinoma redirects to ketolysis for progression under nutrition stress., Huang D, Li T, Wang L, Zhang L, Yan R, Kui Li, Xing S, Wu G, Hu L, Jia W, Lin S, Dang CV, Song L, Gao P, Zhang H., 2016
Awards
- National Science Fund for Distinguished Young Scholars