Professor | Kun Qu | Asia Growth Partners

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Name	Kun Qu
Contact Information	qukun@ustc.edu.cn
Language ability	English, Chinese
Province	Anhui

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Name

Kun Qu

Contact Information

qukun@ustc.edu.cn

Language ability

English, Chinese

Province

Anhui

University/Lab Affiliation and Title	University of Science and Technology of China
Faculty	Basic Medical Sciences
Academic Background & Achievements	2004-2010 PhD in Physical Chemistry: Indiana University, USA 1999-2004 Bachelor's in Chemical Physics: University of Science and Technology of China 2016 National Innovation Talent Youth Fund 2021 National Outstanding Youth Fund
Work Experience	2021.06-present - University of Science and Technology of China - Director of Hong Kong, Macao and Taiwan Affairs Office 2020.08-present - University of Science and Technology of China - Director of International Cooperation and Exchange Department 2019.07-2020.07 - University of Science and Technology of China - Deputy Director of International Cooperation and Exchange Department 2018.12-present - University of Science and Technology of China First Affiliated Hospital - Professor, Doctoral Supervisor 2018.03-present - University of Science and Technology of China School of Big Data - Professor, Doctoral Supervisor 2016.06-present - University of Science and Technology of China School of Life Sciences and Medicine - Professor, Doctoral Supervisor 2010-2016 - Stanford University School of Medicine - Bioinformatics Researcher, Senior Researcher, Center Director 2009-2010 - City of Hope, Beckman Cancer Research Center - Bioinformatics Specialist
Awards	2020: CAS Talent Program Final Evaluation Excellent 2020: School of Life Sciences Academic Career Development Award 2017: CAS Molecular Cell Science Excellence Innovation Center 2017: School of Life Sciences Academic Achievement Award 2017: School of Life Sciences Outstanding Paper Research Award 2016: Overseas High-Level Talent Introduction Youth Project 2007: ORISE Fellowship

University/Lab Affiliation and Title

University of Science and Technology of China

Faculty

Basic Medical Sciences

Academic Background & Achievements

2004-2010 PhD in Physical Chemistry: Indiana University, USA
1999-2004 Bachelor's in Chemical Physics: University of Science and Technology of China
2016 National Innovation Talent Youth Fund
2021 National Outstanding Youth Fund

Work Experience

2021.06-present - University of Science and Technology of China - Director of Hong Kong, Macao and Taiwan Affairs Office
2020.08-present - University of Science and Technology of China - Director of International Cooperation and Exchange Department
2019.07-2020.07 - University of Science and Technology of China - Deputy Director of International Cooperation and Exchange Department
2018.12-present - University of Science and Technology of China First Affiliated Hospital - Professor, Doctoral Supervisor
2018.03-present - University of Science and Technology of China School of Big Data - Professor, Doctoral Supervisor
2016.06-present - University of Science and Technology of China School of Life Sciences and Medicine - Professor, Doctoral Supervisor
2010-2016 - Stanford University School of Medicine - Bioinformatics Researcher, Senior Researcher, Center Director
2009-2010 - City of Hope, Beckman Cancer Research Center - Bioinformatics Specialist

Awards

2020: CAS Talent Program Final Evaluation Excellent
2020: School of Life Sciences Academic Career Development Award
2017: CAS Molecular Cell Science Excellence Innovation Center
2017: School of Life Sciences Academic Achievement Award
2017: School of Life Sciences Outstanding Paper Research Award
2016: Overseas High-Level Talent Introduction Youth Project
2007: ORISE Fellowship

Areas of Focus	Single-cell and spatial omics sequencing technology and algorithm development Application of big data and AI algorithms in cancer and autoimmune diseases Research on the promotion mechanism of extrachromosomal circular DNA in tumorigenesis
Publications	Comparative analysis of methodologies for detecting extrachromosomal circular DNA, Xuyuan Gao, Ke Liu, Songwen Luo, et al, Chuang Guo#, Kun Qu#, 2024 Benchmarking algorithms for single-cell multi-omics prediction and integration, Yinlei Hu, Siyuan Wan, Yuanhanyu Luo, et al, Falai Chen#, Bin Li#, Kun Qu#, 2024 SPACEL: Deep learning-based characterization of spatial transcriptome architectures, Hao Xu, Shuyan Wang, et al, Bin Li#, Jun Lin#, Kun Qu#, 2023 Dynamics and regulation of mitotic chromatin accessibility bookmarking at single-cell resolution, Qiaoni Yu, Xu Liu, Jingwen Fang, Huihui Wu, et al, Zhikai Wang#, Kun Qu#, 2023 Benchmarking spatial and single-cell transcriptomics integration methods for transcript distribution prediction and cell type deconvolution, Bin Li, Wen Zhang, Chuang Guo, et al, Kun Qu#, 2022 Single-cell analysis of COVID-19, sepsis, and HIV infection reveals hyperinflammatory and immunosuppressive signatures in monocytes, Nianping Liu, Chen Jiang, Pengfei Cai, et al, Chuang Guo#, Kun Qu#, 2021 COVID-19 immune features revealed by a large-scale single cell transcriptome atlas, Xianwen Ren, Wen Wen, Xiaoying Fan, Wenhong Hou, Bin Su, Pengfei Cai, Jiesheng Li, Yang Liu, Fei Tang, Fan Zhang, Yu Yang, Jiangping He, Wenji Ma, Jingjing He, Pingping Wang, et al, Peipei Zhang, et al, Penghui Zhou#, Qinghua Jiang#, Zhiwei Huang#, Jin-Xin Bei#, Lai Wei#, Xiu-Wu Bian#, Xindong Liu#, Tao Cheng#, Xiangpan Li#, Pingsen Zhao#, Fu-Sheng Wang#, Hongyang Wang#, Bing Su#, Zheng Zhang#, Kun Qu#, Xiaoqun Wang#, Jiekai Chen#, Ronghua Jin#, Zemin Zhang#, 2021 Chromatin accessibility landscapes of skin cells in systemic sclerosis nominate dendritic cells in disease pathogenesis, Qian Liu, Lisa C. Zaba, et al, Kun Qu# & Howard Y. Chang#, 2020 Single-cell analysis of two severe COVID-19 patients reveals a monocyte-associated and tocilizumab-responding cytokine storm, Chuang Guo, Bin Li, et al, Tengchuan Jin#, Jun Lin# & Kun Qu#, 2020 Chromatin accessibility analysis reveals regulatory dynamics of developing human retina and hiPSC-derived retinal organoids, Haohuan Xie, Wen Zhang, Mei Zhang#, et al, Kun Qu# & Tian Xue#, 2020 Chromatin accessibility landscape of cutaneous T cell lymphoma and dynamic response to HDAC inhibitors, Kun Qu, Lisa C. Zaba, et al, Youn H. Kim# and Howard Y. Chang#, 2017 Integrative genomic analysis by interoperation of bioinformatics tools in GenomeSpace, Kun Qu, Sara Garamszegi, Felix Wu, et al Jill P Mesirov#, 2016 Individuality and variation of personal regulomes in primary human T cells, Kun Qu, Lisa C. Zaba, Paul G. Giresi, et al Howard Y. Chang#, 2015 Landscape and variation of RNA secondary structure across the human transcriptome, Yue Wan#, Kun Qu, et al Howard Y. Chang#, 2014

Areas of Focus

Single-cell and spatial omics sequencing technology and algorithm development
Application of big data and AI algorithms in cancer and autoimmune diseases
Research on the promotion mechanism of extrachromosomal circular DNA in tumorigenesis

Publications

Comparative analysis of methodologies for detecting extrachromosomal circular DNA, Xuyuan Gao*, Ke Liu*, Songwen Luo*, et al, Chuang Guo#, Kun Qu#, 2024
Benchmarking algorithms for single-cell multi-omics prediction and integration, Yinlei Hu*, Siyuan Wan*, Yuanhanyu Luo*, et al, Falai Chen#, Bin Li#, Kun Qu#, 2024
SPACEL: Deep learning-based characterization of spatial transcriptome architectures, Hao Xu*, Shuyan Wang*, et al, Bin Li#, Jun Lin#, Kun Qu#, 2023
Dynamics and regulation of mitotic chromatin accessibility bookmarking at single-cell resolution, Qiaoni Yu*, Xu Liu*, Jingwen Fang*, Huihui Wu*, et al, Zhikai Wang#, Kun Qu#, 2023
Benchmarking spatial and single-cell transcriptomics integration methods for transcript distribution prediction and cell type deconvolution, Bin Li*, Wen Zhang*, Chuang Guo*, et al, Kun Qu#, 2022
Single-cell analysis of COVID-19, sepsis, and HIV infection reveals hyperinflammatory and immunosuppressive signatures in monocytes, Nianping Liu*, Chen Jiang*, Pengfei Cai*, et al, Chuang Guo#, Kun Qu#, 2021
COVID-19 immune features revealed by a large-scale single cell transcriptome atlas, Xianwen Ren*, Wen Wen*, Xiaoying Fan*, Wenhong Hou*, Bin Su*, Pengfei Cai*, Jiesheng Li*, Yang Liu*, Fei Tang*, Fan Zhang*, Yu Yang*, Jiangping He*, Wenji Ma*, Jingjing He*, Pingping Wang*, et al, Peipei Zhang*, et al, Penghui Zhou#, Qinghua Jiang#, Zhiwei Huang#, Jin-Xin Bei#, Lai Wei#, Xiu-Wu Bian#, Xindong Liu#, Tao Cheng#, Xiangpan Li#, Pingsen Zhao#, Fu-Sheng Wang#, Hongyang Wang#, Bing Su#, Zheng Zhang#, Kun Qu#, Xiaoqun Wang#, Jiekai Chen#, Ronghua Jin#, Zemin Zhang#, 2021
Chromatin accessibility landscapes of skin cells in systemic sclerosis nominate dendritic cells in disease pathogenesis, Qian Liu*, Lisa C. Zaba*, et al, Kun Qu# & Howard Y. Chang#, 2020
Single-cell analysis of two severe COVID-19 patients reveals a monocyte-associated and tocilizumab-responding cytokine storm, Chuang Guo*, Bin Li*, et al, Tengchuan Jin#, Jun Lin# & Kun Qu#, 2020
Chromatin accessibility analysis reveals regulatory dynamics of developing human retina and hiPSC-derived retinal organoids, Haohuan Xie*, Wen Zhang*, Mei Zhang*#, et al, Kun Qu# & Tian Xue#, 2020
Chromatin accessibility landscape of cutaneous T cell lymphoma and dynamic response to HDAC inhibitors, Kun Qu*, Lisa C. Zaba*, et al, Youn H. Kim# and Howard Y. Chang#, 2017
Integrative genomic analysis by interoperation of bioinformatics tools in GenomeSpace, Kun Qu*, Sara Garamszegi*, Felix Wu*, et al Jill P Mesirov#, 2016
Individuality and variation of personal regulomes in primary human T cells, Kun Qu*, Lisa C. Zaba*, Paul G. Giresi, et al Howard Y. Chang#, 2015
Landscape and variation of RNA secondary structure across the human transcriptome, Yue Wan*#, Kun Qu*, et al Howard Y. Chang#, 2014

Single-Cell Sequencing Spatial Omics Algorithm Development Big Data Artificial Intelligence Cancer Research Autoimmune Diseases Extrachromosomal Dna Tumorigenesis Bioinformatics

Zhongchao Huang - Central South University

Jiejie Xu - Fudan University

Weijuan Zhang - Fudan University

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