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Kun Qu
Basic Medical Sciences
University of Science and Technology of China
Anhui
Language: English, Chinese
Single-Cell Sequencing
Spatial Omics
Algorithm Development
Big Data
Artificial Intelligence
Cancer Research
Autoimmune Diseases
Extrachromosomal Dna
Tumorigenesis
Bioinformatics
Areas of Focus
- Single-cell and spatial omics sequencing technology and algorithm development
- Application of big data and AI algorithms in cancer and autoimmune diseases
- Research on the promotion mechanism of extrachromosomal circular DNA in tumorigenesis
Work Experience
- 2021.06-present - University of Science and Technology of China - Director of Hong Kong, Macao and Taiwan Affairs Office
- 2020.08-present - University of Science and Technology of China - Director of International Cooperation and Exchange Department
- 2019.07-2020.07 - University of Science and Technology of China - Deputy Director of International Cooperation and Exchange Department
- 2018.12-present - University of Science and Technology of China First Affiliated Hospital - Professor, Doctoral Supervisor
- 2018.03-present - University of Science and Technology of China School of Big Data - Professor, Doctoral Supervisor
- 2016.06-present - University of Science and Technology of China School of Life Sciences and Medicine - Professor, Doctoral Supervisor
- 2010-2016 - Stanford University School of Medicine - Bioinformatics Researcher, Senior Researcher, Center Director
- 2009-2010 - City of Hope, Beckman Cancer Research Center - Bioinformatics Specialist
Academic Background & Achievements
- 2004-2010 PhD in Physical Chemistry: Indiana University, USA
- 1999-2004 Bachelor's in Chemical Physics: University of Science and Technology of China
- 2016 National Innovation Talent Youth Fund
- 2021 National Outstanding Youth Fund
Publications
- Comparative analysis of methodologies for detecting extrachromosomal circular DNA, Xuyuan Gao*, Ke Liu*, Songwen Luo*, et al, Chuang Guo#, Kun Qu#, 2024
- Benchmarking algorithms for single-cell multi-omics prediction and integration, Yinlei Hu*, Siyuan Wan*, Yuanhanyu Luo*, et al, Falai Chen#, Bin Li#, Kun Qu#, 2024
- SPACEL: Deep learning-based characterization of spatial transcriptome architectures, Hao Xu*, Shuyan Wang*, et al, Bin Li#, Jun Lin#, Kun Qu#, 2023
- Dynamics and regulation of mitotic chromatin accessibility bookmarking at single-cell resolution, Qiaoni Yu*, Xu Liu*, Jingwen Fang*, Huihui Wu*, et al, Zhikai Wang#, Kun Qu#, 2023
- Benchmarking spatial and single-cell transcriptomics integration methods for transcript distribution prediction and cell type deconvolution, Bin Li*, Wen Zhang*, Chuang Guo*, et al, Kun Qu#, 2022
- Single-cell analysis of COVID-19, sepsis, and HIV infection reveals hyperinflammatory and immunosuppressive signatures in monocytes, Nianping Liu*, Chen Jiang*, Pengfei Cai*, et al, Chuang Guo#, Kun Qu#, 2021
- COVID-19 immune features revealed by a large-scale single cell transcriptome atlas, Xianwen Ren*, Wen Wen*, Xiaoying Fan*, Wenhong Hou*, Bin Su*, Pengfei Cai*, Jiesheng Li*, Yang Liu*, Fei Tang*, Fan Zhang*, Yu Yang*, Jiangping He*, Wenji Ma*, Jingjing He*, Pingping Wang*, et al, Peipei Zhang*, et al, Penghui Zhou#, Qinghua Jiang#, Zhiwei Huang#, Jin-Xin Bei#, Lai Wei#, Xiu-Wu Bian#, Xindong Liu#, Tao Cheng#, Xiangpan Li#, Pingsen Zhao#, Fu-Sheng Wang#, Hongyang Wang#, Bing Su#, Zheng Zhang#, Kun Qu#, Xiaoqun Wang#, Jiekai Chen#, Ronghua Jin#, Zemin Zhang#, 2021
- Chromatin accessibility landscapes of skin cells in systemic sclerosis nominate dendritic cells in disease pathogenesis, Qian Liu*, Lisa C. Zaba*, et al, Kun Qu# & Howard Y. Chang#, 2020
- Single-cell analysis of two severe COVID-19 patients reveals a monocyte-associated and tocilizumab-responding cytokine storm, Chuang Guo*, Bin Li*, et al, Tengchuan Jin#, Jun Lin# & Kun Qu#, 2020
- Chromatin accessibility analysis reveals regulatory dynamics of developing human retina and hiPSC-derived retinal organoids, Haohuan Xie*, Wen Zhang*, Mei Zhang*#, et al, Kun Qu# & Tian Xue#, 2020
- Chromatin accessibility landscape of cutaneous T cell lymphoma and dynamic response to HDAC inhibitors, Kun Qu*, Lisa C. Zaba*, et al, Youn H. Kim# and Howard Y. Chang#, 2017
- Integrative genomic analysis by interoperation of bioinformatics tools in GenomeSpace, Kun Qu*, Sara Garamszegi*, Felix Wu*, et al Jill P Mesirov#, 2016
- Individuality and variation of personal regulomes in primary human T cells, Kun Qu*, Lisa C. Zaba*, Paul G. Giresi, et al Howard Y. Chang#, 2015
- Landscape and variation of RNA secondary structure across the human transcriptome, Yue Wan*#, Kun Qu*, et al Howard Y. Chang#, 2014
Awards
- 2020: CAS Talent Program Final Evaluation Excellent
- 2020: School of Life Sciences Academic Career Development Award
- 2017: CAS Molecular Cell Science Excellence Innovation Center
- 2017: School of Life Sciences Academic Achievement Award
- 2017: School of Life Sciences Outstanding Paper Research Award
- 2016: Overseas High-Level Talent Introduction Youth Project
- 2007: ORISE Fellowship
