Professor | Jianqiang Bao | Asia Growth Partners

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Name	Jianqiang Bao
Contact Information	BaoLab@ustc.edu.cn
Language ability	English, Chinese
Province	Anhui

Upload Avatar (500 x 500)

Name

Jianqiang Bao

Contact Information

BaoLab@ustc.edu.cn

Language ability

English, Chinese

Province

Anhui

University/Lab Affiliation and Title	University of Science and Technology of China
Faculty	Basic Medical Sciences
Academic Background & Achievements	2010 - PhD in Reproductive Biology: Shanghai Jiao Tong University School of Medicine Published in Nature Communications, Nucleic Acids Research, PNAS, eLife, WIREs RNA
Work Experience	2011-2018 - Postdoctoral Training: University of Nevada Reno and University of Texas MD Anderson Cancer Center

University/Lab Affiliation and Title

University of Science and Technology of China

Faculty

Basic Medical Sciences

Academic Background & Achievements

2010 - PhD in Reproductive Biology: Shanghai Jiao Tong University School of Medicine
Published in Nature Communications, Nucleic Acids Research, PNAS, eLife, WIREs RNA

Work Experience

2011-2018 - Postdoctoral Training: University of Nevada Reno and University of Texas MD Anderson Cancer Center

Areas of Focus	Reproductive cell development and human reproductive disorders Genetic and epigenetic mechanisms in mammalian germ cell development
Publications	The arginine methyltransferase Prmt1 coordinates the germline arginine methylome essential for spermatogonial homeostasis and male fertility., Azhar M, Xu C, Jiang X, Li W, Cao Y, Zhu X, Xing X, Wu L, Zou J, Meng L, Cheng Y, Han W, Bao J., 2023 Maternal NAT10 orchestrates oocyte meiotic cell-cycle progression and maturation in mice., Jiang X, Cheng Y, Zhu Y, Xu C, Li Q, Xing X, Li W, Zou J, Meng L, Azhar M, Cao Y, Tong X, Qin W, Zhu X, Bao J., 2023 Biallelic variants in MAD2L1BP (p31comet) cause female infertility characterized by oocyte maturation arrest., Huang L, Li W, Dai X, Zhao S, Xu B, Wang F, Jin RT, Luo L, Wu L, Jiang X, Cheng Y, Zou J, Xu C, Tong X, Fan HY, Zhao H, Bao J., 2023 Efficient precise integration of large DNA sequences with 3'-overhang dsDNA donors using CRISPR/Cas9., Han W, Li Z, Guo Y, He K, Li W, Xu C, Ge L, He M, Yin X, Zhou J, Li C, Yao D, Bao J, Liang H., 2023 Decoding transcriptional regulation via a human gene expression predictor., Wang Y, Zhang Y, Yu N, Li B, Gong J, Mei Y, Bao J, Ma S., 2023 Optimized protocol for isolation of germ cells from mouse testis by centrifugal elutriation., Cao Y, Meng L, Cheng Y, Azhar M, Jiang X, Xing X, Bao J., 2022 Building RNA-protein germ granules: insights from the multifaceted functions of DEAD-box helicase Vasa/Ddx4 in germline development., Xu C, Cao Y, Bao J., 2021 The Spin1 interactor, Spindoc, is dispensable for meiotic division, but essential for haploid spermatid development in mice., Jiang X, Zhu X, Cheng Y, Azhar M, Xing X, Li W, Cao Y, Shi Q, Bao J., 2021 Towards Post-Meiotic Sperm Production: Genetic Insight into Human Infertility from Mouse Models., Azhar M, Altaf S, Uddin I, Cheng J, Wu L, Tong X, Qin W, Bao J., 2021 Exome sequencing shines in empty follicle syndrome: zona pellucida gene mutations manifest genuine empty follicle syndrome., Altaf S, Bao J., 2021 A novel homozygous nonsense ZP1 variant causes human female infertility associated with empty follicle syndrome (EFS)., Xu Q, Zhu X, Maqsood M, Li W, Tong X, Kong S, Wang F, Liu X, Wei Z, Zhang Z, Zhu F, Cao Y, Bao J., 2020 A DNAH17 missense variant causes flagella destabilization and asthenozoospermia., Zhang B, Ma H, Khan T, Ma A, Li T, Zhang H, Gao J, Zhou J, Li Y, Yu C, Bao J, Ali A, Murtaza G, Yin H, Gao Q, Jiang X, Zhang F, Liu C, Khan I, Zubair M, Hussain HMJ, Khan R, Yousaf A, Yuan L, Lu Y, Xu X, Wang Y, Tao Q, Hao Q, Fang H, Cheng H, Zhang Y, Shi Q., 2020 PRMT6 Promotes Lung Tumor Progression via the Alternate Activation of Tumor-Associated Macrophages., Avasarala S, Wu PY, Khan SQ, Yanlin S, Van Scoyk M, Bao J, Di Lorenzo A, David O, Bedford MT, Gupta V, Winn RA, Bikkavilli RK., 2020 Npat-dependent programmed Sertoli cell proliferation is indispensable for testis cord development and germ cell mitotic arrest., Jiang X, Yin S, Fan S, Bao J, Jiao Y, Ali A, Iqbal F, Xu J, Zhang Y, Shi Q., 2019 Mouse Models of Overexpression Reveal Distinct Oncogenic Roles for Different Type I Protein Arginine Methyltransferases., Bao J, Di Lorenzo A, Lin K, Lu Y, Zhong Y, Sebastian MM, Muller WJ, Yang Y, Bedford MT., 2019

Areas of Focus

Reproductive cell development and human reproductive disorders
Genetic and epigenetic mechanisms in mammalian germ cell development

Publications

The arginine methyltransferase Prmt1 coordinates the germline arginine methylome essential for spermatogonial homeostasis and male fertility., Azhar M, Xu C, Jiang X, Li W, Cao Y, Zhu X, Xing X, Wu L, Zou J, Meng L, Cheng Y, Han W, Bao J., 2023
Maternal NAT10 orchestrates oocyte meiotic cell-cycle progression and maturation in mice., Jiang X, Cheng Y, Zhu Y, Xu C, Li Q, Xing X, Li W, Zou J, Meng L, Azhar M, Cao Y, Tong X, Qin W, Zhu X, Bao J., 2023
Biallelic variants in MAD2L1BP (p31comet) cause female infertility characterized by oocyte maturation arrest., Huang L, Li W, Dai X, Zhao S, Xu B, Wang F, Jin RT, Luo L, Wu L, Jiang X, Cheng Y, Zou J, Xu C, Tong X, Fan HY, Zhao H, Bao J., 2023
Efficient precise integration of large DNA sequences with 3'-overhang dsDNA donors using CRISPR/Cas9., Han W, Li Z, Guo Y, He K, Li W, Xu C, Ge L, He M, Yin X, Zhou J, Li C, Yao D, Bao J, Liang H., 2023
Decoding transcriptional regulation via a human gene expression predictor., Wang Y, Zhang Y, Yu N, Li B, Gong J, Mei Y, Bao J, Ma S., 2023
Optimized protocol for isolation of germ cells from mouse testis by centrifugal elutriation., Cao Y, Meng L, Cheng Y, Azhar M, Jiang X, Xing X, Bao J., 2022
Building RNA-protein germ granules: insights from the multifaceted functions of DEAD-box helicase Vasa/Ddx4 in germline development., Xu C, Cao Y, Bao J., 2021
The Spin1 interactor, Spindoc, is dispensable for meiotic division, but essential for haploid spermatid development in mice., Jiang X, Zhu X, Cheng Y, Azhar M, Xing X, Li W, Cao Y, Shi Q, Bao J., 2021
Towards Post-Meiotic Sperm Production: Genetic Insight into Human Infertility from Mouse Models., Azhar M, Altaf S, Uddin I, Cheng J, Wu L, Tong X, Qin W, Bao J., 2021
Exome sequencing shines in empty follicle syndrome: zona pellucida gene mutations manifest genuine empty follicle syndrome., Altaf S, Bao J., 2021
A novel homozygous nonsense ZP1 variant causes human female infertility associated with empty follicle syndrome (EFS)., Xu Q, Zhu X, Maqsood M, Li W, Tong X, Kong S, Wang F, Liu X, Wei Z, Zhang Z, Zhu F, Cao Y, Bao J., 2020
A DNAH17 missense variant causes flagella destabilization and asthenozoospermia., Zhang B, Ma H, Khan T, Ma A, Li T, Zhang H, Gao J, Zhou J, Li Y, Yu C, Bao J, Ali A, Murtaza G, Yin H, Gao Q, Jiang X, Zhang F, Liu C, Khan I, Zubair M, Hussain HMJ, Khan R, Yousaf A, Yuan L, Lu Y, Xu X, Wang Y, Tao Q, Hao Q, Fang H, Cheng H, Zhang Y, Shi Q., 2020
PRMT6 Promotes Lung Tumor Progression via the Alternate Activation of Tumor-Associated Macrophages., Avasarala S, Wu PY, Khan SQ, Yanlin S, Van Scoyk M, Bao J, Di Lorenzo A, David O, Bedford MT, Gupta V, Winn RA, Bikkavilli RK., 2020
Npat-dependent programmed Sertoli cell proliferation is indispensable for testis cord development and germ cell mitotic arrest., Jiang X, Yin S, Fan S, Bao J, Jiao Y, Ali A, Iqbal F, Xu J, Zhang Y, Shi Q., 2019
Mouse Models of Overexpression Reveal Distinct Oncogenic Roles for Different Type I Protein Arginine Methyltransferases., Bao J, Di Lorenzo A, Lin K, Lu Y, Zhong Y, Sebastian MM, Muller WJ, Yang Y, Bedford MT., 2019

Reproductive Health Germ Cells Genetic Mechanisms Epigenetics Fertility Birth Defects Molecular Biology Cell Biology Mouse Models Environmental Factors

Lian Dong Zuo - Guangzhou Medical University

Guo-Gang Xing - Peking University

Xiaowei Zhang - Peking University

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