Professor | Jin Tengchuan | Asia Growth Partners

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Name	Jin Tengchuan
Contact Information	jint@ustc.edu.cn
Language ability	English, Chinese
Province	Anhui

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Name

Jin Tengchuan

Contact Information

jint@ustc.edu.cn

Language ability

English, Chinese

Province

Anhui

University/Lab Affiliation and Title	University of Science and Technology of China
Faculty	Basic Medical Sciences
Academic Background & Achievements	1998-2003: Bachelor's degrees in Biology and Business Administration from University of Science and Technology of China 2003-2008: PhD in Molecular Biochemistry and Biophysics from Illinois Institute of Technology 2008: Sigma Xi Award for Outstanding Doctoral Graduate
Work Experience	2008-2014: Postdoc Fellow and Research Fellow at NIH, NIAID, Laboratory of Immunology 2015-present: Full-time teaching at University of Science and Technology of China
Awards	2008: Sigma Xi Award for Outstanding Doctoral Graduate

University/Lab Affiliation and Title

University of Science and Technology of China

Faculty

Basic Medical Sciences

Academic Background & Achievements

1998-2003: Bachelor's degrees in Biology and Business Administration from University of Science and Technology of China
2003-2008: PhD in Molecular Biochemistry and Biophysics from Illinois Institute of Technology
2008: Sigma Xi Award for Outstanding Doctoral Graduate

Work Experience

2008-2014: Postdoc Fellow and Research Fellow at NIH, NIAID, Laboratory of Immunology
2015-present: Full-time teaching at University of Science and Technology of China

Awards

2008: Sigma Xi Award for Outstanding Doctoral Graduate

Areas of Focus	Structural basis of the innate immune system Molecular mechanisms of pathogen-host interactions Molecular mechanisms of inflammatory responses and autoimmune diseases Protein engineering and protein drug development
Publications	Identification, Characterization, Cloning, and Cross-Reactivity of Zan b 2, a Novel Pepper Allergen of 11S Legumin., Hu J, Zhu LP, Wang RQ, Zhu L, Chen F, Hou Y, Ni K, Deng S, Liu S, Ying W, Sun JL, Li H, Jin T, 2024 A new pepper allergen Zan b 1.01 of 2S albumins: Identification, cloning, characterization, and cross-reactivity., Li H, Zhu L, Wang RQ, Zhu L, Hu J, Chen F, Ma L, Tang R, Liu S, Ni K, Ye X, Zhang Y, Sun JL, Jin T, 2024 IL-4-secreting CD40L+ MAIT cells support antibody production in the peripheral blood of Heonch-Schönlein purpura patients., Liu M, Yang Z, Wu Q, Yang Y, Zhao D, Cheng Q, Li Y, Liu G, Zhao C, Pan J, Zhang Y, Deng F, Jin T, 2023 Kyasanur Forest disease virus NS3 helicase: Insights into structure, activity, and inhibitors., Zhang C, Li Y, Samad A, He H, Ma H, Chen Y, Jin T, 2023 Advances in Etiopathological Role and Control of HPV in Cervical Cancer Oncogenesis., Kombe AJK, Zoa-Assoumou S, Bounda GA, Nsole-Biteghe FA, Jin T, Zouré AA, 2023 An engineered bispecific nanobody in tetrameric secretory IgA format confers broad neutralization against SARS-CoV-1&2 and most variants., Zeng W, Jia X, Chi X, Zhang X, Li E, Wu Y, Liu Y, Han J, Ni K, Ye X, Hu X, Ma H, Yu C, Chiu S, Jin T, 2023 Antibody responses following the surge of SARS-CoV-2 Omicron infection among patients with systemic autoimmune rheumatic diseases., Xiang N, Li YJ, Liu MY, Wu QQ, Zhang YX, Jin HZ, Wang Q, Li YW, Tong DL, Xue T, Jin T, Bao W, Chen Z, 2023 Selection, identification and crystal structure of shark-derived single-domain antibodies against a green fluorescent protein., Chen YL, Xie XX, Zheng P, Zhu C, Ma H, Khalid Z, Xie YJ, Dang YZ, Ye Y, Sheng N, Zhong N, Lei WH, Zhang C, Zhang LJ, Jin T, Cao MJ, 2023 Structural mechanism of dsDNA recognition by the hMNDA HIN domain: New insights into the DNA-binding model of a PYHIN protein., Li Y, Zhang C, Samad A, Zheng P, Li Y, Chen F, Jin T, 2023

Areas of Focus

Structural basis of the innate immune system
Molecular mechanisms of pathogen-host interactions
Molecular mechanisms of inflammatory responses and autoimmune diseases
Protein engineering and protein drug development

Publications

Identification, Characterization, Cloning, and Cross-Reactivity of Zan b 2, a Novel Pepper Allergen of 11S Legumin., Hu J, Zhu LP, Wang RQ, Zhu L, Chen F, Hou Y, Ni K, Deng S, Liu S, Ying W, Sun JL, Li H, Jin T, 2024
A new pepper allergen Zan b 1.01 of 2S albumins: Identification, cloning, characterization, and cross-reactivity., Li H, Zhu L, Wang RQ, Zhu L, Hu J, Chen F, Ma L, Tang R, Liu S, Ni K, Ye X, Zhang Y, Sun JL, Jin T, 2024
IL-4-secreting CD40L+ MAIT cells support antibody production in the peripheral blood of Heonch-Schönlein purpura patients., Liu M, Yang Z, Wu Q, Yang Y, Zhao D, Cheng Q, Li Y, Liu G, Zhao C, Pan J, Zhang Y, Deng F, Jin T, 2023
Kyasanur Forest disease virus NS3 helicase: Insights into structure, activity, and inhibitors., Zhang C, Li Y, Samad A, He H, Ma H, Chen Y, Jin T, 2023
Advances in Etiopathological Role and Control of HPV in Cervical Cancer Oncogenesis., Kombe AJK, Zoa-Assoumou S, Bounda GA, Nsole-Biteghe FA, Jin T, Zouré AA, 2023
An engineered bispecific nanobody in tetrameric secretory IgA format confers broad neutralization against SARS-CoV-1&2 and most variants., Zeng W, Jia X, Chi X, Zhang X, Li E, Wu Y, Liu Y, Han J, Ni K, Ye X, Hu X, Ma H, Yu C, Chiu S, Jin T, 2023
Antibody responses following the surge of SARS-CoV-2 Omicron infection among patients with systemic autoimmune rheumatic diseases., Xiang N, Li YJ, Liu MY, Wu QQ, Zhang YX, Jin HZ, Wang Q, Li YW, Tong DL, Xue T, Jin T, Bao W, Chen Z, 2023
Selection, identification and crystal structure of shark-derived single-domain antibodies against a green fluorescent protein., Chen YL, Xie XX, Zheng P, Zhu C, Ma H, Khalid Z, Xie YJ, Dang YZ, Ye Y, Sheng N, Zhong N, Lei WH, Zhang C, Zhang LJ, Jin T, Cao MJ, 2023
Structural mechanism of dsDNA recognition by the hMNDA HIN domain: New insights into the DNA-binding model of a PYHIN protein., Li Y, Zhang C, Samad A, Zheng P, Li Y, Chen F, Jin T, 2023

Innate Immunity Structural Biology Pathogen-Host Interaction Molecular Mechanism Inflammation Autoimmune Disease Protein Engineering Drug Development Antibody Immunotherapy

Ling Chen - Guangzhou Medical University

Qi Tang - Nanjing Medical University

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