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Jin Tengchuan
Basic Medical Sciences
University of Science and Technology of China
Anhui
Language: English, Chinese
Innate Immunity
Structural Biology
Pathogen-Host Interaction
Molecular Mechanism
Inflammation
Autoimmune Disease
Protein Engineering
Drug Development
Antibody
Immunotherapy
Areas of Focus
- Structural basis of the innate immune system
- Molecular mechanisms of pathogen-host interactions
- Molecular mechanisms of inflammatory responses and autoimmune diseases
- Protein engineering and protein drug development
Work Experience
- 2008-2014: Postdoc Fellow and Research Fellow at NIH, NIAID, Laboratory of Immunology
- 2015-present: Full-time teaching at University of Science and Technology of China
Academic Background & Achievements
- 1998-2003: Bachelor's degrees in Biology and Business Administration from University of Science and Technology of China
- 2003-2008: PhD in Molecular Biochemistry and Biophysics from Illinois Institute of Technology
- 2008: Sigma Xi Award for Outstanding Doctoral Graduate
Publications
- Identification, Characterization, Cloning, and Cross-Reactivity of Zan b 2, a Novel Pepper Allergen of 11S Legumin., Hu J, Zhu LP, Wang RQ, Zhu L, Chen F, Hou Y, Ni K, Deng S, Liu S, Ying W, Sun JL, Li H, Jin T, 2024
- A new pepper allergen Zan b 1.01 of 2S albumins: Identification, cloning, characterization, and cross-reactivity., Li H, Zhu L, Wang RQ, Zhu L, Hu J, Chen F, Ma L, Tang R, Liu S, Ni K, Ye X, Zhang Y, Sun JL, Jin T, 2024
- IL-4-secreting CD40L+ MAIT cells support antibody production in the peripheral blood of Heonch-Schönlein purpura patients., Liu M, Yang Z, Wu Q, Yang Y, Zhao D, Cheng Q, Li Y, Liu G, Zhao C, Pan J, Zhang Y, Deng F, Jin T, 2023
- Kyasanur Forest disease virus NS3 helicase: Insights into structure, activity, and inhibitors., Zhang C, Li Y, Samad A, He H, Ma H, Chen Y, Jin T, 2023
- Advances in Etiopathological Role and Control of HPV in Cervical Cancer Oncogenesis., Kombe AJK, Zoa-Assoumou S, Bounda GA, Nsole-Biteghe FA, Jin T, Zouré AA, 2023
- An engineered bispecific nanobody in tetrameric secretory IgA format confers broad neutralization against SARS-CoV-1&2 and most variants., Zeng W, Jia X, Chi X, Zhang X, Li E, Wu Y, Liu Y, Han J, Ni K, Ye X, Hu X, Ma H, Yu C, Chiu S, Jin T, 2023
- Antibody responses following the surge of SARS-CoV-2 Omicron infection among patients with systemic autoimmune rheumatic diseases., Xiang N, Li YJ, Liu MY, Wu QQ, Zhang YX, Jin HZ, Wang Q, Li YW, Tong DL, Xue T, Jin T, Bao W, Chen Z, 2023
- Selection, identification and crystal structure of shark-derived single-domain antibodies against a green fluorescent protein., Chen YL, Xie XX, Zheng P, Zhu C, Ma H, Khalid Z, Xie YJ, Dang YZ, Ye Y, Sheng N, Zhong N, Lei WH, Zhang C, Zhang LJ, Jin T, Cao MJ, 2023
- Structural mechanism of dsDNA recognition by the hMNDA HIN domain: New insights into the DNA-binding model of a PYHIN protein., Li Y, Zhang C, Samad A, Zheng P, Li Y, Chen F, Jin T, 2023
Awards
- 2008: Sigma Xi Award for Outstanding Doctoral Graduate
