Professor | Chunlei Cang | Asia Growth Partners

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Name	Chunlei Cang
Contact Information	ccang@ustc.edu.cn
Language ability	English, Chinese
Province	Anhui

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Name

Chunlei Cang

Contact Information

ccang@ustc.edu.cn

Language ability

English, Chinese

Province

Anhui

University/Lab Affiliation and Title	University of Science and Technology of China
Faculty	Basic Medical Sciences
Academic Background & Achievements	1999-2003: Bachelor of Science, Fudan University 2003-2009: Ph.D. in Neurobiology, Fudan University 2009-2014: Postdoctoral Research, University of Pennsylvania 2014-2015: Assistant Researcher, University of Pennsylvania 2015-present: Joined University of Science and Technology of China
Work Experience	2009-2014: Postdoctoral Research, University of Pennsylvania 2014-2015: Assistant Researcher, University of Pennsylvania 2015-present: Professor, University of Science and Technology of China

University/Lab Affiliation and Title

University of Science and Technology of China

Faculty

Basic Medical Sciences

Academic Background & Achievements

1999-2003: Bachelor of Science, Fudan University
2003-2009: Ph.D. in Neurobiology, Fudan University
2009-2014: Postdoctoral Research, University of Pennsylvania
2014-2015: Assistant Researcher, University of Pennsylvania
2015-present: Joined University of Science and Technology of China

Work Experience

2009-2014: Postdoctoral Research, University of Pennsylvania
2014-2015: Assistant Researcher, University of Pennsylvania
2015-present: Professor, University of Science and Technology of China

Areas of Focus	Characteristics, functions, and modulation of lysosomal membrane ion channels Role of lysosomal and other organelle ion channels in intracellular signal transduction Mechanism of diseases related to organelle ion channels and development of new drugs targeting these channels
Publications	TMEM175 is an Organelle K(+) Channel Regulating Lysosomal Function, Cang, C., Aranda, K., Seo, YJ., Gasnier, B., Ren, D., 2015 mTOR Regulates Lysosomal ATP-sensitive Two-Pore Na+ Channels to Adapt to Metabolic State, Cang, C., Zhou, Y., Navarro, B., Aranda, K., Shi, L., Battaglia-Hsu, S., Nissim, I., Clapham, D. and Ren, D., 2013 A non-inactivating high-voltage-activated two-pore Na+ channel that supports ultra-long action potentials and membrane bistability, Cang, C., Aranda, K., Ren, D., 2014 The voltage-gated sodium channel TPC1 confers endolysosomal excitability, Cang, C., Bekele, B., Ren, D., 2014 PKCepsilon-dependent potentiation of TTX-resistant Nav1.8 current by neurokinin-1 receptor activation in rat dorsal root ganglion neurons, Cang CL, Zhang H, Zhang YQ, Zhao ZQ, 2009 Neurokinin-1 receptor enhances TRPV1 activity in primary sensory neurons via PKCe: a novel pathway for heat hyperalgesia, Zhang H., Cang CL, Kawasaki Y, Liang LL, Zhang YQ, Ji RR, Zhao ZQ, 2007 Thermal nociception in adult Drosophila: behavioral characterization and the role of the painless gene, Xu SY, Cang CL, Liu XF, Peng YQ, Ye YZ, Zhao ZQ, Guo AK, 2006

Areas of Focus

Characteristics, functions, and modulation of lysosomal membrane ion channels
Role of lysosomal and other organelle ion channels in intracellular signal transduction
Mechanism of diseases related to organelle ion channels and development of new drugs targeting these channels

Publications

TMEM175 is an Organelle K(+) Channel Regulating Lysosomal Function, Cang, C., Aranda, K., Seo, YJ., Gasnier, B., Ren, D., 2015
mTOR Regulates Lysosomal ATP-sensitive Two-Pore Na+ Channels to Adapt to Metabolic State, Cang, C., Zhou, Y., Navarro, B., Aranda, K., Shi, L., Battaglia-Hsu, S., Nissim, I., Clapham, D. and Ren, D., 2013
A non-inactivating high-voltage-activated two-pore Na+ channel that supports ultra-long action potentials and membrane bistability, Cang, C.*, Aranda, K., Ren, D.*, 2014
The voltage-gated sodium channel TPC1 confers endolysosomal excitability, Cang, C.*, Bekele, B., Ren, D.*, 2014
PKCepsilon-dependent potentiation of TTX-resistant Nav1.8 current by neurokinin-1 receptor activation in rat dorsal root ganglion neurons, Cang CL, Zhang H, Zhang YQ, Zhao ZQ, 2009
Neurokinin-1 receptor enhances TRPV1 activity in primary sensory neurons via PKCe: a novel pathway for heat hyperalgesia, Zhang H., Cang CL, Kawasaki Y, Liang LL, Zhang YQ, Ji RR, Zhao ZQ, 2007
Thermal nociception in adult Drosophila: behavioral characterization and the role of the painless gene, Xu SY, Cang CL, Liu XF, Peng YQ, Ye YZ, Zhao ZQ, Guo AK, 2006

Lysosomal Membrane Ion Channels Signal Transduction Intracellular Disease Mechanism Drug Development Potassium Channels Sodium Channels Membrane Potential Electrophysiology

Chunlei Cang - University of Science and Technology of China

Lei Han - Wuhan University

Li Yuehua - Nanjing Medical University

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