Upload Avatar (500 x 500)
Ying Chen
Life Science
Xiamen University
Fujian
Language: English, Chinese
Myelination
Glial Cells
Molecular Mechanisms
Epigenetics
Chromatin Remodeling
Differentiation
Disease
Signaling Pathways
Gpcr
Regeneration
Areas of Focus
- Molecular mechanisms of myelinating glial cell development and disease
- Epigenetic and chromatin remodeling control of myelinating cell differentiation and disease
- Signaling mechanisms in glial differentiation and regeneration
Work Experience
- 2007-2012 - UTSW Medical Center - Postdoctoral Fellow
- 2013-Present - Xiamen University, School of Life Sciences - Professor
Academic Background & Achievements
- 1996 - B.S. in Biochemistry: Fudan University
- 1999 - M.S. in Pathogenic Organisms: Chinese Academy of Preventive Medicine
- 2006 - Ph.D. in Immunology and Microbiology: Rush University
Publications
- A GPR17-cAMP-Lactate Signaling Axis in Oligodendrocytes Regulates Whole-Body Metabolism., Ou Z, Ma Y, Sun Y, Zheng G, Wang S, Xing R, Chen X, Han Y, Wang J, Lu QR, Zhao TJ, Chen Y., 2019
- Olig2-Targeted G-Protein-Coupled Receptor Gpr17 Regulates Oligodendrocyte Survival in Response to Lysolecithin-Induced Demyelination., Ou Z, Sun Y, Lin L, You N, Liu X, Li H, Ma Y, Cao L, Han Y, Liu M, Deng Y, Yao L, Lu QR, Chen Y., 2016
- Olig2 Targets Chromatin Remodelers To Enhancers To Initiate Oligodendrocyte Differentiation., Yu Y, Y. Chen, B. Kim, H. Wang, C. Zhao, X. He, L. Liu, W. Liu, L. M. N. Wu, M. Mao, J. R. Chan, J. Wu and Q. R. Lu, 2013
- HDAC-mediated Deacetylation of NF-κB is Critical for Schwann cell Myelination., Ying Chen, Haibo Wang, Sung Ok Yoon, Xiaomei Xu, Michael Hottiger, Haesun Kim, Eric N. Olson, and Q. Richard Lu., 2011
- The oligodendrocyte-specific G-protein coupled receptor GPR17 is a cell intrinsic timer of myelination., Chen, Y. H. Wu, S. Wang, H. Koito, J. Li, J. Hoang, F. Ye, S. S. Escobar, A. Gow, H. A. Arnett, B. D. Trapp, N. J. Karandikar, J. Hsieh and Q. R. Lu., 2009
- The basic helix-loop-helix transcription factor olig2 is critical for reactive astrocyte proliferation after cortical injury., Chen Y, Miles DK, Hoang T, Shi J, Hurlock E, Kernie SG, Lu QR., 2008
