Professor | Ying Chen | Asia Growth Partners

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Name	Ying Chen
Contact Information	yingchen@xmu.edu.cn
Language ability	English, Chinese
Province	Fujian

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Name

Ying Chen

Contact Information

yingchen@xmu.edu.cn

Language ability

English, Chinese

Province

Fujian

University/Lab Affiliation and Title	Xiamen University
Faculty	Life Sciences
Academic Background & Achievements	1996 - B.S. in Biochemistry: Fudan University 1999 - M.S. in Pathogenic Organisms: Chinese Academy of Preventive Medicine 2006 - Ph.D. in Immunology and Microbiology: Rush University
Work Experience	2007-2012 - UTSW Medical Center - Postdoctoral Fellow 2013-Present - Xiamen University, School of Life Sciences - Professor

University/Lab Affiliation and Title

Xiamen University

Faculty

Life Sciences

Academic Background & Achievements

1996 - B.S. in Biochemistry: Fudan University
1999 - M.S. in Pathogenic Organisms: Chinese Academy of Preventive Medicine
2006 - Ph.D. in Immunology and Microbiology: Rush University

Work Experience

2007-2012 - UTSW Medical Center - Postdoctoral Fellow
2013-Present - Xiamen University, School of Life Sciences - Professor

Areas of Focus	Molecular mechanisms of myelinating glial cell development and disease Epigenetic and chromatin remodeling control of myelinating cell differentiation and disease Signaling mechanisms in glial differentiation and regeneration
Publications	A GPR17-cAMP-Lactate Signaling Axis in Oligodendrocytes Regulates Whole-Body Metabolism., Ou Z, Ma Y, Sun Y, Zheng G, Wang S, Xing R, Chen X, Han Y, Wang J, Lu QR, Zhao TJ, Chen Y., 2019 Olig2-Targeted G-Protein-Coupled Receptor Gpr17 Regulates Oligodendrocyte Survival in Response to Lysolecithin-Induced Demyelination., Ou Z, Sun Y, Lin L, You N, Liu X, Li H, Ma Y, Cao L, Han Y, Liu M, Deng Y, Yao L, Lu QR, Chen Y., 2016 Olig2 Targets Chromatin Remodelers To Enhancers To Initiate Oligodendrocyte Differentiation., Yu Y, Y. Chen, B. Kim, H. Wang, C. Zhao, X. He, L. Liu, W. Liu, L. M. N. Wu, M. Mao, J. R. Chan, J. Wu and Q. R. Lu, 2013 HDAC-mediated Deacetylation of NF-κB is Critical for Schwann cell Myelination., Ying Chen, Haibo Wang, Sung Ok Yoon, Xiaomei Xu, Michael Hottiger, Haesun Kim, Eric N. Olson, and Q. Richard Lu., 2011 The oligodendrocyte-specific G-protein coupled receptor GPR17 is a cell intrinsic timer of myelination., Chen, Y. H. Wu, S. Wang, H. Koito, J. Li, J. Hoang, F. Ye, S. S. Escobar, A. Gow, H. A. Arnett, B. D. Trapp, N. J. Karandikar, J. Hsieh and Q. R. Lu., 2009 The basic helix-loop-helix transcription factor olig2 is critical for reactive astrocyte proliferation after cortical injury., Chen Y, Miles DK, Hoang T, Shi J, Hurlock E, Kernie SG, Lu QR., 2008

Areas of Focus

Molecular mechanisms of myelinating glial cell development and disease
Epigenetic and chromatin remodeling control of myelinating cell differentiation and disease
Signaling mechanisms in glial differentiation and regeneration

Publications

A GPR17-cAMP-Lactate Signaling Axis in Oligodendrocytes Regulates Whole-Body Metabolism., Ou Z, Ma Y, Sun Y, Zheng G, Wang S, Xing R, Chen X, Han Y, Wang J, Lu QR, Zhao TJ, Chen Y., 2019
Olig2-Targeted G-Protein-Coupled Receptor Gpr17 Regulates Oligodendrocyte Survival in Response to Lysolecithin-Induced Demyelination., Ou Z, Sun Y, Lin L, You N, Liu X, Li H, Ma Y, Cao L, Han Y, Liu M, Deng Y, Yao L, Lu QR, Chen Y., 2016
Olig2 Targets Chromatin Remodelers To Enhancers To Initiate Oligodendrocyte Differentiation., Yu Y, Y. Chen, B. Kim, H. Wang, C. Zhao, X. He, L. Liu, W. Liu, L. M. N. Wu, M. Mao, J. R. Chan, J. Wu and Q. R. Lu, 2013
HDAC-mediated Deacetylation of NF-κB is Critical for Schwann cell Myelination., Ying Chen, Haibo Wang, Sung Ok Yoon, Xiaomei Xu, Michael Hottiger, Haesun Kim, Eric N. Olson, and Q. Richard Lu., 2011
The oligodendrocyte-specific G-protein coupled receptor GPR17 is a cell intrinsic timer of myelination., Chen, Y. H. Wu, S. Wang, H. Koito, J. Li, J. Hoang, F. Ye, S. S. Escobar, A. Gow, H. A. Arnett, B. D. Trapp, N. J. Karandikar, J. Hsieh and Q. R. Lu., 2009
The basic helix-loop-helix transcription factor olig2 is critical for reactive astrocyte proliferation after cortical injury., Chen Y, Miles DK, Hoang T, Shi J, Hurlock E, Kernie SG, Lu QR., 2008

Myelination Glial Cells Molecular Mechanisms Epigenetics Chromatin Remodeling Differentiation Disease Signaling Pathways Gpcr Regeneration

Zhiye Wang - Zhejiang University

Xingwang Deng - Peking University

Yan Song - Peking University

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