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Huang Tianzhi
Life Science
Xiamen University
Fujian
Language: Chinese, English
Cancer Stem Cells
Glioma
Signaling Pathways
Autophagy
Ferroptosis
Protein Modifications
Tumorigenesis
Progression
Therapy
Glioma Treatment
Areas of Focus
- Cancer stem cells
- Glioma stem cells
- Signaling pathways
- Cell autophagy
- Ferroptosis
- Protein posttranslational modifications
- Tumorigenesis
- Tumor progression
- Therapy responses
- Clinical treatment of glioma
Work Experience
- 2013-2018 - Northwestern University - Postdoctoral Fellow
- 2018-2021 - Northwestern University - Research Assistant Professor
- 2021-Present - Xiamen University - Professor
Academic Background & Achievements
- 2007 - B.S. in Bio-engineering: Fujian Normal University
- 2010 - M.S. in Biochemistry and Molecular Biology: Xiamen University
- 2013 - Ph.D. in Biochemistry and Molecular Biology: Zhejiang University
Publications
- MST4 Phosphorylation of ATG4B Regulates Autophagic Activity, Tumorigenicity, and Radioresistance in Glioblastoma., Huang T, Kim CK, Alvarez AA, Pangeni RP, Wan X, Song X, Shi T, Yang Y, Sastry N, Horbinski CM, Lu S, Stupp R, Kessler JA, Nishikawa R, Nakano I, Sulman EP, Lu X, James CD, Yin XM, Hu B, Cheng SY., 2017
- PRMT6 Methylation of RCC1 Regulates Mitosis, Tumorigenicity, and Radiation Response of Glioblastoma Stem Cells., Huang T, Yang Y, Song X, Wan X, Wu B, Sastry N, Horbinski CM, Zeng C, Tiek D, Goenka A, Liu F, Brennan CW, Kessler JA, Stupp R, Nakano I, Sulman EP, Nishikawa R, James CD, Zhang W, Xu W, Hu B, Cheng SY., 2021
- A regulatory circuit of miR-125b/miR-20b and Wnt signalling controls glioblastoma phenotypes through FZD6-modulated pathways., Huang T, Alvarez AA, Pangeni RP, Horbinski CM, Lu S, Kim SH, James CD, J Raizer J, A Kessler J, Brenann CW, Sulman EP, Finocchiaro G, Tan M, Nishikawa R, Lu X, Nakano I, Hu B, Cheng SY., 2016
- MIR93 (microRNA -93) Regulates Tumorigenicity and Therapy Response of Glioblastoma by Targeting Autophagy., Huang T, Wan X, Alvarez AA, James CD, Song X, Yang Y, Sastry N, Nakano I, Sulman EP, Hu B, Cheng SY., 2019
- Stem cell programs in cancer initiation, progression, and therapy resistance., Huang T, Song X, Xu D, Tiek D, Goenka A, Wu B, Sastry N, Hu B, Cheng SY., 2020
