Professor | Yongyou Zhang | Asia Growth Partners

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Name	Yongyou Zhang
Contact Information	yongyouzhang@xmu.edu.cn
Language ability	English, Chinese
Province	Fujian

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Name

Yongyou Zhang

Contact Information

yongyouzhang@xmu.edu.cn

Language ability

English, Chinese

Province

Fujian

University/Lab Affiliation and Title	Xiamen University
Faculty	Life Sciences
Academic Background & Achievements	2000 - B.S. in Biotechnology: Xiamen University 2003 - M.S. in Biochemistry and Molecular Biology: Xiamen University 2008 - Ph.D. in Biomedicine: Texas A&M University
Work Experience	2009-2015 - Case Western Reserve University - Postdoctoral Fellow/Research Scientist 2016-Present - Xiamen University, School of Life Sciences - Professor
Awards	2019 - Xiamen City 'Outstanding Youth' 2019 - Xiamen City 'Double Hundred Plan' 2020 - Fujian Province High-Level Talent

University/Lab Affiliation and Title

Xiamen University

Faculty

Life Sciences

Academic Background & Achievements

2000 - B.S. in Biotechnology: Xiamen University
2003 - M.S. in Biochemistry and Molecular Biology: Xiamen University
2008 - Ph.D. in Biomedicine: Texas A&M University

Work Experience

2009-2015 - Case Western Reserve University - Postdoctoral Fellow/Research Scientist
2016-Present - Xiamen University, School of Life Sciences - Professor

Awards

2019 - Xiamen City 'Outstanding Youth'
2019 - Xiamen City 'Double Hundred Plan'
2020 - Fujian Province High-Level Talent

Areas of Focus	Cancer Metabolism and Ferroptosis Epigenetics and Targeting Drug Screening System Development Multi-Omics for Cancer Biomarker Discovery and Early Cancer Diagnosis AI-aided Drug Design and Biomaterial Development Synthesis Biology and IVD Enzyme Development
Publications	Hydrogen sulfide-mediated persulfidation regulates homocysteine metabolism and enhances ferroptosis in non-small-cell lung cancer, Zheng H, Chen H, Cai Y, Shen M, Li X, Han Y, Deng X, Cao H, Liu j, Liu B, LI G, Wang X, Chen H, Hou J, Lin S-H, Zong L, Zhang Y, 2024 ATF3-CBS signaling axis coordinates ferroptosis and tumorigenesis in colorectal cancer, Liu J, Lu X, Zeng S, Fu R, Wang X, Luo L, Huang T, Deng X, Zheng H, Ma S, Ning D, Zong L, Lin SH, Zhang Y, 2024 METTL17 coordinates ferroptosis and tumorigenesis by regulating mitochondrial translation in colorectal cancer, Li H, Yu K, Hu H, Zhang X, Zeng S, Li J, Dong X, Deng X, Zhang J, Zhang Y, 2024 YTHDF1 shapes immune-mediated hepatitis via regulating inflammatory cell recruitment and response, Li H, Yu K, Zhang X, Li J, Hu h, Deng X, Zeng S, Dong X, Zhao J, Zhang Y, 2024 Characterization and humanization of VNARs targeting human serum albumin from the whitespotted bamboo shark (Chiloscyllium plagiosum), Li W, Chen M, Wang T, Feng X, Jiang X, Dong X, Zhang H, Tang X, Tian R, Zhang Y, Li Z, 2024 CovidShiny: An Integrated Web Tool for SARS-CoV-2 Mutation Profiling and Molecular Diagnosis Assay Evaluation In Silico, Ma S, Xiao G, Deng X, Tong M, Huang J, Li Q, Zhang Y, 2023 Nuclear receptor coactivator SRC-1 promotes colorectal cancer progression through enhancing GLI2-mediated Hedgehog signaling, Guo P, Chen Q, Peng K, Xie J, Liu J, Ren W, Tong Z, Li M, Zhang Y, Yu C, Mo P, 2022 Accessible and Adaptable Multiplexed Real-Time PCR Approaches to Identify SARS-CoV-2 Variants of Concern, Yan T, Xu Y, Zheng R, Zeng X, Chen Z, Lin S, Xia Z, Liao Y, Zhang Y, Li Q, 2022 Profiling chromatin regulatory landscape: insights into the development of ChIP-seq and ATAC-seq, Ma S; Zhang Y, 2020 Inhibitors of 15- Prostaglandin Dehydrogenase To Potentiate Tissue Repair, Antczak MI, Zhang Y#, Wang C, Doran J, Naidoo J, Voruganti S, et al., 2017 Inhibition of the Prostaglandin Degrading Enzyme 15-PGDH Potentiates Tissue Regeneration, Y. Zhang#, A, Desai# S. Yang# K. Bae#, M. Antczak#, S. Fink, S#. Tiwari#, et al. S.D. Markowitz, 2015 The Mst1 and Mst2 kinases restrain intestinal stem cell proliferation and colonic tumorigenesis by inhibition of Yap overabundance, D. Zhou, Y. Zhang#, H. Wu, E. Barry, Y. Yi, E. Lawrence, D. Dawson J.E. Willis, S.D. Markowitz, F.D. Camargo and J. Avruch, 2011 Role of epithelial cell fibroblast growth factor receptor substrate 2a in prostate development, regeneration and tumorigenesis, Y. Zhang#, J. Zhang, Y. Lin, Y. Lan, C. Lin, J.W. Xuan, M.M. Shen, W.L. McKeehan,N.M. Greenberg, and F. Wang, 2008

Areas of Focus

Cancer Metabolism and Ferroptosis
Epigenetics and Targeting Drug Screening System Development
Multi-Omics for Cancer Biomarker Discovery and Early Cancer Diagnosis
AI-aided Drug Design and Biomaterial Development
Synthesis Biology and IVD Enzyme Development

Publications

Hydrogen sulfide-mediated persulfidation regulates homocysteine metabolism and enhances ferroptosis in non-small-cell lung cancer, Zheng H, Chen H, Cai Y, Shen M, Li X, Han Y, Deng X, Cao H, Liu j, Liu B, LI G, Wang X, Chen H, Hou J, Lin S-H, Zong L, Zhang Y*, 2024
ATF3-CBS signaling axis coordinates ferroptosis and tumorigenesis in colorectal cancer, Liu J, Lu X, Zeng S, Fu R, Wang X, Luo L, Huang T, Deng X, Zheng H, Ma S, Ning D, Zong L, Lin SH, Zhang Y*, 2024
METTL17 coordinates ferroptosis and tumorigenesis by regulating mitochondrial translation in colorectal cancer, Li H, Yu K, Hu H, Zhang X, Zeng S, Li J, Dong X, Deng X, Zhang J, Zhang Y*, 2024
YTHDF1 shapes immune-mediated hepatitis via regulating inflammatory cell recruitment and response, Li H, Yu K, Zhang X, Li J, Hu h, Deng X, Zeng S, Dong X, Zhao J, Zhang Y*, 2024
Characterization and humanization of VNARs targeting human serum albumin from the whitespotted bamboo shark (Chiloscyllium plagiosum), Li W, Chen M, Wang T, Feng X, Jiang X, Dong X, Zhang H, Tang X, Tian R, Zhang Y*, Li Z*, 2024
CovidShiny: An Integrated Web Tool for SARS-CoV-2 Mutation Profiling and Molecular Diagnosis Assay Evaluation In Silico, Ma S, Xiao G, Deng X, Tong M, Huang J, Li Q, Zhang Y, 2023
Nuclear receptor coactivator SRC-1 promotes colorectal cancer progression through enhancing GLI2-mediated Hedgehog signaling, Guo P, Chen Q, Peng K, Xie J, Liu J, Ren W, Tong Z, Li M, Zhang Y*, Yu C*, Mo P*, 2022
Accessible and Adaptable Multiplexed Real-Time PCR Approaches to Identify SARS-CoV-2 Variants of Concern, Yan T, Xu Y, Zheng R, Zeng X, Chen Z, Lin S, Xia Z, Liao Y, Zhang Y*, Li Q*, 2022
Profiling chromatin regulatory landscape: insights into the development of ChIP-seq and ATAC-seq, Ma S; Zhang Y*, 2020
Inhibitors of 15- Prostaglandin Dehydrogenase To Potentiate Tissue Repair, Antczak MI*, Zhang Y#, Wang C, Doran J, Naidoo J, Voruganti S, et al., 2017
Inhibition of the Prostaglandin Degrading Enzyme 15-PGDH Potentiates Tissue Regeneration, Y. Zhang#, A, Desai# S. Yang# K. Bae#, M. Antczak#, S. Fink, S#. Tiwari#, et al. S.D. Markowitz, 2015
The Mst1 and Mst2 kinases restrain intestinal stem cell proliferation and colonic tumorigenesis by inhibition of Yap overabundance, D. Zhou*, Y. Zhang#, H. Wu, E. Barry, Y. Yi, E. Lawrence, D. Dawson J.E. Willis, S.D. Markowitz, F.D. Camargo and J. Avruch, 2011
Role of epithelial cell fibroblast growth factor receptor substrate 2a in prostate development, regeneration and tumorigenesis, Y. Zhang#, J. Zhang, Y. Lin, Y. Lan, C. Lin, J.W. Xuan, M.M. Shen, W.L. McKeehan,N.M. Greenberg, and F. Wang, 2008

Cancer Metabolism Ferroptosis Epigenetics Drug Screening Multi-Omics Biomarker Ai Biomaterials Synthesis Biology

Zhi John Lu - Tsinghua University

Zhi John Lu - Tsinghua University

Ruixin Zhu - Tongji University

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