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Yongyou Zhang
Life Science
Xiamen University
Fujian
Language: English, Chinese
Cancer
Metabolism
Ferroptosis
Epigenetics
Drug Screening
Multi-Omics
Biomarker
Ai
Biomaterials
Synthesis Biology
Areas of Focus
- Cancer Metabolism and Ferroptosis
- Epigenetics and Targeting Drug Screening System Development
- Multi-Omics for Cancer Biomarker Discovery and Early Cancer Diagnosis
- AI-aided Drug Design and Biomaterial Development
- Synthesis Biology and IVD Enzyme Development
Work Experience
- 2009-2015 - Case Western Reserve University - Postdoctoral Fellow/Research Scientist
- 2016-Present - Xiamen University, School of Life Sciences - Professor
Academic Background & Achievements
- 2000 - B.S. in Biotechnology: Xiamen University
- 2003 - M.S. in Biochemistry and Molecular Biology: Xiamen University
- 2008 - Ph.D. in Biomedicine: Texas A&M University
Publications
- Hydrogen sulfide-mediated persulfidation regulates homocysteine metabolism and enhances ferroptosis in non-small-cell lung cancer, Zheng H, Chen H, Cai Y, Shen M, Li X, Han Y, Deng X, Cao H, Liu j, Liu B, LI G, Wang X, Chen H, Hou J, Lin S-H, Zong L, Zhang Y*, 2024
- ATF3-CBS signaling axis coordinates ferroptosis and tumorigenesis in colorectal cancer, Liu J, Lu X, Zeng S, Fu R, Wang X, Luo L, Huang T, Deng X, Zheng H, Ma S, Ning D, Zong L, Lin SH, Zhang Y*, 2024
- METTL17 coordinates ferroptosis and tumorigenesis by regulating mitochondrial translation in colorectal cancer, Li H, Yu K, Hu H, Zhang X, Zeng S, Li J, Dong X, Deng X, Zhang J, Zhang Y*, 2024
- YTHDF1 shapes immune-mediated hepatitis via regulating inflammatory cell recruitment and response, Li H, Yu K, Zhang X, Li J, Hu h, Deng X, Zeng S, Dong X, Zhao J, Zhang Y*, 2024
- Characterization and humanization of VNARs targeting human serum albumin from the whitespotted bamboo shark (Chiloscyllium plagiosum), Li W, Chen M, Wang T, Feng X, Jiang X, Dong X, Zhang H, Tang X, Tian R, Zhang Y*, Li Z*, 2024
- CovidShiny: An Integrated Web Tool for SARS-CoV-2 Mutation Profiling and Molecular Diagnosis Assay Evaluation In Silico, Ma S, Xiao G, Deng X, Tong M, Huang J, Li Q, Zhang Y, 2023
- Nuclear receptor coactivator SRC-1 promotes colorectal cancer progression through enhancing GLI2-mediated Hedgehog signaling, Guo P, Chen Q, Peng K, Xie J, Liu J, Ren W, Tong Z, Li M, Zhang Y*, Yu C*, Mo P*, 2022
- Accessible and Adaptable Multiplexed Real-Time PCR Approaches to Identify SARS-CoV-2 Variants of Concern, Yan T, Xu Y, Zheng R, Zeng X, Chen Z, Lin S, Xia Z, Liao Y, Zhang Y*, Li Q*, 2022
- Profiling chromatin regulatory landscape: insights into the development of ChIP-seq and ATAC-seq, Ma S; Zhang Y*, 2020
- Inhibitors of 15- Prostaglandin Dehydrogenase To Potentiate Tissue Repair, Antczak MI*, Zhang Y#, Wang C, Doran J, Naidoo J, Voruganti S, et al., 2017
- Inhibition of the Prostaglandin Degrading Enzyme 15-PGDH Potentiates Tissue Regeneration, Y. Zhang#, A, Desai# S. Yang# K. Bae#, M. Antczak#, S. Fink, S#. Tiwari#, et al. S.D. Markowitz, 2015
- The Mst1 and Mst2 kinases restrain intestinal stem cell proliferation and colonic tumorigenesis by inhibition of Yap overabundance, D. Zhou*, Y. Zhang#, H. Wu, E. Barry, Y. Yi, E. Lawrence, D. Dawson J.E. Willis, S.D. Markowitz, F.D. Camargo and J. Avruch, 2011
- Role of epithelial cell fibroblast growth factor receptor substrate 2a in prostate development, regeneration and tumorigenesis, Y. Zhang#, J. Zhang, Y. Lin, Y. Lan, C. Lin, J.W. Xuan, M.M. Shen, W.L. McKeehan,N.M. Greenberg, and F. Wang, 2008
Awards
- 2019 - Xiamen City 'Outstanding Youth'
- 2019 - Xiamen City 'Double Hundred Plan'
- 2020 - Fujian Province High-Level Talent
