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Dawang Zhou
dwzhou@xmu.edu.cn
English, Chinese
Fujian

Academic Information

Xiamen University
Life Sciences
  • 1998 - B.S. in Organic Chemistry: Xiamen University
  • 2002 - M.S. in Biochemistry: The City University of New York
  • 2006 - Ph.D. in Microbiology and Immunology: Yeshiva University
  • 2016 - National Outstanding Youth Science Fund
  • 2018 - Changjiang Scholar Award Program
  • 2006-2009 - Harvard Medical School - Postdoctoral Fellow
  • 2009-2011 - Harvard Medical School - Instructor in Medicine
  • 2011-Now - Xiamen University, School of Life Sciences - Professor
  • 2012-2017 - Xiamen University, School of Life Sciences - Vice Dean
  • 2017-2020 - Xiamen University, School of Life Sciences - Dean
  • 2020-Now - Xiamen University - Vice President
  • Science Exploration Award (Life Sciences), 2022
  • 15th Tan Jiazhen Life Science Innovation Award, 2022
  • Fujian Provincial Natural Science First Prize, 2020
  • Innovation Research Group Project (Leader), 2020
  • Government Special Allowance Expert, 2019
  • 7th 'China Overseas Contribution Award', 2018
  • Changjiang Scholar Award Program, 2018
  • Promega Innovation Award, 2017
  • National Key R&D Program Project (Chief Scientist), 2017
  • Young and Middle-aged Science and Technology Innovation Leading Talent, 2017
  • National Outstanding Youth Science Fund, 2016

Research

Biological functions and regulatory mechanisms of the Hippo signaling pathway
  • Osr2 functions as a biomechanical checkpoint to aggravate CD8+ T cell exhaustion in tumor., Jinjia Zhang, Junhong Li, Yongqiang Hou, Yao Lin, Hao Zhao, Yiran Shi, Kaiyun Chen, Cheng Nian, Jiayu Tang, Lei Pan, Yunzhi Xing, Huan Gao, Bingying Yang, Zengfang Song, Yao Cheng, Yue Liu, Min Sun, Yueyue Linghu, Jiaxin Li, Haitao Huang, Zhangjian Lai, Zhien Zhou, Zifeng Li, Xiufeng Sun, Qinghua Chen, Dongxue Su, Wengang Li, Zhihai Peng, Pingguo Liu, Wei Chen, Hongling Huang, Yixin Chen, Bailong Xiao, Lilin Ye, Lanfen Chen, Dawang Zhou, 2024
  • SPTAN1/NUMB axis senses cell density to restrain cell growth and oncogenesis through Hippo signaling., Dongxue Su, Yuxi Li, Weiji Zhang, Huan Gao, Yao Cheng, Yongqiang Hou, Junhong Li, Yi Ye, Zhangjian Lai, Zhe Li, Haitao Huang, Jiaxin Li, Jinhuan Li, Mengyu Cheng, Cheng Nian, Na Wu, Zhien Zhou, Yunzhi Xing, He Liu, Jiayu Tang, Yu Zhao, Qinghua Chen, Lixin Hong, Wengang Li, Zhihai Peng, Bin Zhao, Randy L. Johnson, Pingguo Liu, Wanjin Hong, Lanfen Chen, Dawang Zhou, 2023
  • Glycogen accumulation and phase separation drives liver tumor initiation., Qingxu Liu, Jiaxin Li, Weiji Zhang, Chen Xiao, Shihao Zhang, Cheng Nian, Junhong Li, Dongxue Su, Lihong Chen, Qian Zhao, Hui Shao, Hao Zhao, Qinghua Chen, Yuxi Li, Jing Geng, Lixin Hong, Shuhai Lin, Qiao Wu, Xianming Deng, Rongqin Ke, Jin Ding, Randy L. Johnson, Xiaolong Liu, Lanfen Chen, Dawang Zhou, 2021
  • TLR4 signalling via Piezo1 engages and enhances the macrophage mediated host response during bacterial infection., Jing Geng, Yiran Shi, Jinjia Zhang, Bingying Yang, Ping Wang, Weihong Yuan, Hao Zhao, Junhong Li, Funiu Qin, Lixin Hong, Changchuan Xie, Xianming Deng, Yujie Sun, Congying Wu, Lanfen Chen, Dawang Zhou, 2021
  • FGF15 Activates Hippo Signaling to Suppress Bile Acid Metabolism and Liver Tumorigenesis., Suyuan Ji, Qingxu Liu, Shihao Zhang, Qinghua Chen, Cong Wang, Weiji Zhang, Chen Xiao, Yuxi Li, Cheng Nian, Jiaxin Li, Junhong Li, Jing Geng, Lixin Hong, Changchuan Xie, Ying He, Xing Chen, Xun Li, Zhen-Yu Yin, Han You, Kwang-Huei Lin, Qiao Wu, Chundong Yu, Randy L. Johnson, Li Wang, Lanfen Chen, Fen Wang, Dawang Zhou, 2019
  • Hippo Signaling Suppresses Cell Ploidy and Tumorigenesis through Skp2., Shihao Zhang, Qinghua Chen, Qingxu Liu, Yuxi Li, Xiufeng Sun, Lixin Hong, Suyuan Ji, Chenyan Liu, Jing Geng, Weiji Zhang, Zhonglei Lu, Zhen-Yu Yin, Yuanyuan Zeng, Kwang-Huei Lin, Qiao Wu, Qiyuan Li, Keiko Nakayama, Keiich I Nakayama, Xianming Deng, Randy L Johnson, Liang Zhu, Daming Gao, Lanfen Chen, Dawang Zhou, 2017
  • The transcriptional coactivator TAZ regulates reciprocal differentiation of TH17 cells and Treg cells., Jing Geng, Shujuan Yu, Hao Zhao, Xiufeng Sun, Xun Li, Ping Wang, Xiaolin Xiong, Lixin Hong, Changchuan Xie, Jiahui Gao, Yiran Shi, Jiaqi Peng, Randy L Johnson, Nengming Xiao, Linrong Lu, Jiahuai Han, Dawang Zhou, Lanfen Chen, 2017
  • Pharmacological targeting of kinases MST1 and MST2 augments tissue repair and regeneration., Fuqin Fan, Zhixiang He, Lu-Lu Kong, Qinghua Chen, Quan Yuan, Shihao Zhang, Jinjin Ye, Hao Liu, Xiufeng Sun, Jing Geng, Lunzhi Yuan, Lixin Hong, Chen Xiao, Weiji Zhang, Xihuan Sun, Yunzhan Li, Ping Wang, Lihong Huang, Xinrui Wu, Zhiliang Ji, Qiao Wu, Ning-Shao Xia, Nathanael S Gray, Lanfen Chen, Cai-Hong Yun, Xianming Deng, Dawang Zhou, 2016
  • Kinases Mst1 and Mst2 positively regulate phagocytic induction of reactive oxygen species and bactericidal activity., Jing Geng, Xiufeng Sun, Ping Wang, Shihao Zhang, Xiaozhen Wang, Hongtan Wu, Lixin Hong, Changchuan Xie, Xun Li, Hao Zhao, Qingxu Liu, Mingting Jiang, Qinghua Chen, Jinjia Zhang, Yang Li, Siyang Song, Hong-Rui Wang, Rongbin Zhou, Randy L Johnson, Kun-Yi Chien, Sheng-Cai Lin, Jiahuai Han, Joseph Avruch, Lanfen Chen, Dawang Zhou, 2015
  • Integration of Hippo signalling and the unfolded protein response to restrain liver overgrowth and tumorigenesis., Hongtan Wu, Luyao Wei, Fuqin Fan, Suyuan Ji, Shihao Zhang, Jing Geng, Lixin Hong, Xin Fan, Qinghua Chen, Jing Tian, Mingting Jiang, Xiufeng Sun, Changnan Jin, Zhen-Yu Yin, Qingxu Liu, Jinjia Zhang, Funiu Qin, Kwang-Huei Lin, Jau-Song Yu, Xianming Deng, Hong-Rui Wang, Bin Zhao, Randy L Johnson, Lanfen Chen, Dawang Zhou, 2015
  • The Ets Transcription Factor GABP Is a Component of the Hippo Pathway Essential for Growth and Antioxidant Defense., Hongtan Wu, Yubo Xiao, Shihao Zhang, Suyuan Ji, Luyao Wei, Fuqin Fan, Jing Geng, Jing Tian, Xiufeng Sun, Funiu Qin, Changnan Jin, Jianjun Lin, Zhen-Yu Yin, Ting Zhang, Lianzhong Luo, Yang Li, Siyang Song, Sheng-Cai Lin, Xianming Deng, Fernando Camargo, Joseph Avruch, Lanfen Chen, Dawang Zhou, 2013
  • The Mst1 and Mst2 kinases control activation of rho family GTPases and thymic egress of mature thymocytes., Fan Mou, Maria Praskova, Fan Xia, Denille Van Buren, Hanno Hock, Joseph Avruch, Dawang Zhou, 2012
Keywords
Hippo Pathway Mst1/2 Kinases Organ Size Regulation Tissue Growth Cell Proliferation Cell Adhesion Cell Migration Immune Disorders Cancer Targeted Intervention
Related Professors
Changdong Lin - Tongji University
Area of Focus
Cell Adhesion | Signaling | Development | Infection | Immunity | Cancer | Aging | Molecular Mechanisms | Pathophysiology | Therapeutic Interventions
Songcheng Zhu - Tongji University
Area of Focus
Hats | Hdacs | Cancer | Cell Cycle | Tumor | Autophagy | Lung Cancer | Cell Proliferation | Cell Signaling | Gene Regulation
Dan Ying Chen - Peking University
Area of Focus
Nf-Κb | Transcription Factor | Cell Signaling | Regulatory Mechanisms | Pathogen Infection | Tumor | Cancer | Immune Response | Inflammation | Cell Proliferation
View All
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