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周大旺
dwzhou@xmu.edu.cn
英语, 中文
福建
厦门大学
Life Sciences
  • 1998年 - 厦门大学有机化学专业,学士学位
  • 2002年 - 美国纽约城市大学生物化学专业,硕士学位
  • 2006年 - 美国耶希瓦大学微生物与免疫学专业,博士学位
  • 2016年 - 国家杰出青年科学基金
  • 2018年 - 长江学者奖励计划
  • 2006-2009年 - 哈佛大学医学院 - 博士后
  • 2009-2011年 - 哈佛大学医学院 - 讲师
  • 2011年至今 - 厦门大学生命科学学院 - 教授
  • 2012-2017年 - 厦门大学生命科学学院 - 副院长
  • 2017-2020年 - 厦门大学生命科学学院 - 院长
  • 2020年至今 - 厦门大学 - 副校长
  • 科学探索奖(生命科学领域),2022年
  • 第十五届谈家桢生命科学创新奖,2022年
  • 福建省自然科学一等奖,2020年
  • 创新研究群体项目(负责人),2020年
  • 政府特殊津贴专家,2019年
  • 第七届“中国侨界贡献奖”,2018年
  • 长江学者奖励计划,2018年
  • 普洛麦格创新奖,2017年
  • 国家重点研发计划项目(首席科学家),2017年
  • 中青年科技创新领军人才,2017年
  • 国家杰出青年科学基金,2016年
Hippo信号通路的生物学功能和调控机制
  • Osr2 functions as a biomechanical checkpoint to aggravate CD8+ T cell exhaustion in tumor., Jinjia Zhang, Junhong Li, Yongqiang Hou, Yao Lin, Hao Zhao, Yiran Shi, Kaiyun Chen, Cheng Nian, Jiayu Tang, Lei Pan, Yunzhi Xing, Huan Gao, Bingying Yang, Zengfang Song, Yao Cheng, Yue Liu, Min Sun, Yueyue Linghu, Jiaxin Li, Haitao Huang, Zhangjian Lai, Zhien Zhou, Zifeng Li, Xiufeng Sun, Qinghua Chen, Dongxue Su, Wengang Li, Zhihai Peng, Pingguo Liu, Wei Chen, Hongling Huang, Yixin Chen, Bailong Xiao, Lilin Ye, Lanfen Chen, Dawang Zhou, 2024
  • SPTAN1/NUMB axis senses cell density to restrain cell growth and oncogenesis through Hippo signaling., Dongxue Su, Yuxi Li, Weiji Zhang, Huan Gao, Yao Cheng, Yongqiang Hou, Junhong Li, Yi Ye, Zhangjian Lai, Zhe Li, Haitao Huang, Jiaxin Li, Jinhuan Li, Mengyu Cheng, Cheng Nian, Na Wu, Zhien Zhou, Yunzhi Xing, He Liu, Jiayu Tang, Yu Zhao, Qinghua Chen, Lixin Hong, Wengang Li, Zhihai Peng, Bin Zhao, Randy L. Johnson, Pingguo Liu, Wanjin Hong, Lanfen Chen, Dawang Zhou, 2023
  • Glycogen accumulation and phase separation drives liver tumor initiation., Qingxu Liu, Jiaxin Li, Weiji Zhang, Chen Xiao, Shihao Zhang, Cheng Nian, Junhong Li, Dongxue Su, Lihong Chen, Qian Zhao, Hui Shao, Hao Zhao, Qinghua Chen, Yuxi Li, Jing Geng, Lixin Hong, Shuhai Lin, Qiao Wu, Xianming Deng, Rongqin Ke, Jin Ding, Randy L. Johnson, Xiaolong Liu, Lanfen Chen, Dawang Zhou, 2021
  • TLR4 signalling via Piezo1 engages and enhances the macrophage mediated host response during bacterial infection., Jing Geng, Yiran Shi, Jinjia Zhang, Bingying Yang, Ping Wang, Weihong Yuan, Hao Zhao, Junhong Li, Funiu Qin, Lixin Hong, Changchuan Xie, Xianming Deng, Yujie Sun, Congying Wu, Lanfen Chen, Dawang Zhou, 2021
  • FGF15 Activates Hippo Signaling to Suppress Bile Acid Metabolism and Liver Tumorigenesis., Suyuan Ji, Qingxu Liu, Shihao Zhang, Qinghua Chen, Cong Wang, Weiji Zhang, Chen Xiao, Yuxi Li, Cheng Nian, Jiaxin Li, Junhong Li, Jing Geng, Lixin Hong, Changchuan Xie, Ying He, Xing Chen, Xun Li, Zhen-Yu Yin, Han You, Kwang-Huei Lin, Qiao Wu, Chundong Yu, Randy L. Johnson, Li Wang, Lanfen Chen, Fen Wang, Dawang Zhou, 2019
  • Hippo Signaling Suppresses Cell Ploidy and Tumorigenesis through Skp2., Shihao Zhang, Qinghua Chen, Qingxu Liu, Yuxi Li, Xiufeng Sun, Lixin Hong, Suyuan Ji, Chenyan Liu, Jing Geng, Weiji Zhang, Zhonglei Lu, Zhen-Yu Yin, Yuanyuan Zeng, Kwang-Huei Lin, Qiao Wu, Qiyuan Li, Keiko Nakayama, Keiich I Nakayama, Xianming Deng, Randy L Johnson, Liang Zhu, Daming Gao, Lanfen Chen, Dawang Zhou, 2017
  • The transcriptional coactivator TAZ regulates reciprocal differentiation of TH17 cells and Treg cells., Jing Geng, Shujuan Yu, Hao Zhao, Xiufeng Sun, Xun Li, Ping Wang, Xiaolin Xiong, Lixin Hong, Changchuan Xie, Jiahui Gao, Yiran Shi, Jiaqi Peng, Randy L Johnson, Nengming Xiao, Linrong Lu, Jiahuai Han, Dawang Zhou, Lanfen Chen, 2017
  • Pharmacological targeting of kinases MST1 and MST2 augments tissue repair and regeneration., Fuqin Fan, Zhixiang He, Lu-Lu Kong, Qinghua Chen, Quan Yuan, Shihao Zhang, Jinjin Ye, Hao Liu, Xiufeng Sun, Jing Geng, Lunzhi Yuan, Lixin Hong, Chen Xiao, Weiji Zhang, Xihuan Sun, Yunzhan Li, Ping Wang, Lihong Huang, Xinrui Wu, Zhiliang Ji, Qiao Wu, Ning-Shao Xia, Nathanael S Gray, Lanfen Chen, Cai-Hong Yun, Xianming Deng, Dawang Zhou, 2016
  • Kinases Mst1 and Mst2 positively regulate phagocytic induction of reactive oxygen species and bactericidal activity., Jing Geng, Xiufeng Sun, Ping Wang, Shihao Zhang, Xiaozhen Wang, Hongtan Wu, Lixin Hong, Changchuan Xie, Xun Li, Hao Zhao, Qingxu Liu, Mingting Jiang, Qinghua Chen, Jinjia Zhang, Yang Li, Siyang Song, Hong-Rui Wang, Rongbin Zhou, Randy L Johnson, Kun-Yi Chien, Sheng-Cai Lin, Jiahuai Han, Joseph Avruch, Lanfen Chen, Dawang Zhou, 2015
  • Integration of Hippo signalling and the unfolded protein response to restrain liver overgrowth and tumorigenesis., Hongtan Wu, Luyao Wei, Fuqin Fan, Suyuan Ji, Shihao Zhang, Jing Geng, Lixin Hong, Xin Fan, Qinghua Chen, Jing Tian, Mingting Jiang, Xiufeng Sun, Changnan Jin, Zhen-Yu Yin, Qingxu Liu, Jinjia Zhang, Funiu Qin, Kwang-Huei Lin, Jau-Song Yu, Xianming Deng, Hong-Rui Wang, Bin Zhao, Randy L Johnson, Lanfen Chen, Dawang Zhou, 2015
  • The Ets Transcription Factor GABP Is a Component of the Hippo Pathway Essential for Growth and Antioxidant Defense., Hongtan Wu, Yubo Xiao, Shihao Zhang, Suyuan Ji, Luyao Wei, Fuqin Fan, Jing Geng, Jing Tian, Xiufeng Sun, Funiu Qin, Changnan Jin, Jianjun Lin, Zhen-Yu Yin, Ting Zhang, Lianzhong Luo, Yang Li, Siyang Song, Sheng-Cai Lin, Xianming Deng, Fernando Camargo, Joseph Avruch, Lanfen Chen, Dawang Zhou, 2013
  • The Mst1 and Mst2 kinases control activation of rho family GTPases and thymic egress of mature thymocytes., Fan Mou, Maria Praskova, Fan Xia, Denille Van Buren, Hanno Hock, Joseph Avruch, Dawang Zhou, 2012
Hippo信号通路 Mst1/2激酶 器官大小调控 组织生长 细胞增殖 细胞粘附 细胞迁移 免疫失调 癌症 靶向干预

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