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Kai-Rui Mao
Life Science
Xiamen University
Fujian
Language: English, Chinese
Gut Microbiota
Immune System
Host Physiology
Pathology
Nervous System
Immune Function
Tumorigenesis
Cancer Therapy
Tissue Homeostasis
Genomic Technologies
Areas of Focus
- Interaction between gut microbiota and immune system
Work Experience
- 2011-2013 - Research Assistant: Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences
- 2013-2019 - Visiting Fellow: National Institute of Allergy and Infectious Diseases, National Institutes of Health
- 2019-Present - Principal Investigator of Mucosal Immunology Group: School of Life Sciences, Xiamen University
Academic Background & Achievements
- 2004 - Bachelor's Degree in Biotechnology: Shandong Normal University
- 2011 - Ph.D. in Cell Biology: Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences
Publications
- Thinking differently about ILCs-Not just tissue resident and not just the same as CD4(+) T-cell effectors, Huang, Y.#*, Mao, K.#*, and Germain, R. N., 2018
- Innate and adaptive lymphocytes sequentially shape the gut microbiota and lipid metabolism, Mao, K.*, Baptista, A. P., Tamoutounour, S., Zhuang, L., Bouladoux, N., Martins, A. J., Huang, Y., Gerner, M. Y., Belkaid, Y., and Germain, R. N.*, 2018
- S1P-dependent interorgan trafficking of group 2 innate lymphoid cells supports host defense, Huang, Y.*#, Mao, K. #, Chen, X., Sun, M. A., Kawabe, T., Li, W., Usher, N., Zhu, J., Urban, J. F., Jr., Paul, W. E., and Germain, R. N.*, 2018
- Nitric oxide suppresses NLRP3 inflammasome activation and protects against LPS-induced septic shock, Mao, K. #, Chen, S. #, Chen, M., Ma, Y., Wang, Y., Huang, B., He, Z., Zeng, Y., Hu, Y., Sun, S., Li, J., Wu, X., Wang, X., Strober, W., Chen, C.*, Meng, G.*, and Sun, B*., 2013
- beta-arrestin1 is critical for the full activation of NLRP3 and NLRC4 inflammasomes, Mao, K. #, Chen, S. #, Wang, Y. #, Zeng, Y., Ma, Y., Hu, Y., Zhang, H., Sun, S., Wu, X., Meng, G., Pei, G.*, and Sun, B*., 2015
- Group 3 innate lymphoid cells continuously require the transcription factor GATA-3 after commitment, Zhong, C., Cui, K., Wilhelm, C., Hu, G., Mao, K., Belkaid, Y., Zhao, K., and Zhu, J*., 2016
- Cellular localization of NLRP3 inflammasome, Wang, Y., Yang, C., Mao, K., Chen, S., Meng, G.*, and Sun, B*., 2013
- Tripartite-motif protein 30 negatively regulates NLRP3 inflammasome activation by modulating reactive oxygen species production, Hu, Y. #, Mao, K. #, Zeng, Y., Chen, S., Tao, Z., Yang, C., Sun, S., Wu, X., Meng, G., and Sun, B*., 2010
- Trichosanthin functions as Th2-type adjuvant in induction of allergic airway inflammation, Wang, Y., Mao, K., Sun, S., Lin, G., Wu, X., Yao, G., and Sun, B*., 2009
- TRIM30 alpha negatively regulates TLR-mediated NF-kappa B activation by targeting TAB2 and TAB3 for degradation, Shi, M. #, Deng, W. #, Bi, E., Mao, K., Ji, Y., Lin, G., Wu, X., Tao, Z., Li, Z., Cai, X., Sun, S., Xiang, C.*, and Sun, B*., 2008
