Professor | Guo Fu | Asia Growth Partners

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Name	Guo Fu
Contact Information	guofu@xmu.edu.cn
Language ability	English, Chinese
Province	Fujian

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Name

Guo Fu

Contact Information

guofu@xmu.edu.cn

Language ability

English, Chinese

Province

Fujian

University/Lab Affiliation and Title	Xiamen University
Faculty	Medical
Academic Background & Achievements	1999/06-2004/08 PhD: University of Melbourne, Department of Microbiology and Immunology 1995/09-1998/06 Master's: China Medical University, Department of Immunology 1991/09-1995/07 Bachelor's: Liaoning University, Department of Biology
Work Experience	2019/12-Present - Xiamen University, School of Medicine/State Key Laboratory of Cellular Stress Biology - Professor 2014/10-2019/12 - Xiamen University, School of Life Sciences/State Key Laboratory of Cellular Stress Biology - Professor 2010/11-2014/08 - The Scripps Research Institute, Department of Immunology and Microbiology - Staff Scientist 2004/10-2010/10 - The Scripps Research Institute, Department of Immunology and Microbiology - Postdoctoral Researcher 1998/07-1999/06 - China Medical University, Department of Immunology - Assistant Lecturer

University/Lab Affiliation and Title

Xiamen University

Faculty

Medical

Academic Background & Achievements

1999/06-2004/08 PhD: University of Melbourne, Department of Microbiology and Immunology
1995/09-1998/06 Master's: China Medical University, Department of Immunology
1991/09-1995/07 Bachelor's: Liaoning University, Department of Biology

Work Experience

2019/12-Present - Xiamen University, School of Medicine/State Key Laboratory of Cellular Stress Biology - Professor
2014/10-2019/12 - Xiamen University, School of Life Sciences/State Key Laboratory of Cellular Stress Biology - Professor
2010/11-2014/08 - The Scripps Research Institute, Department of Immunology and Microbiology - Staff Scientist
2004/10-2010/10 - The Scripps Research Institute, Department of Immunology and Microbiology - Postdoctoral Researcher
1998/07-1999/06 - China Medical University, Department of Immunology - Assistant Lecturer

Areas of Focus	T cell function and molecular mechanisms in normal and disease states Tumor immunity Anti-infection immunity Autoimmune diseases Mass spectrometry flow cytometry and imaging techniques
Publications	Synthetic lethality of combined AT-101 with idarubicin in acute myeloid leukemia via blockade of DNA repair and activation of intrinsic apoptotic pathway., Yang Q, Chen K, Zhang L, Feng L, Fu G, Jiang S, Bi S, Lin C, Zhou Y, Zhao H, Chen XL, Fu G, Xu B, 2019 Unique CDR3 epitope targeting by CAR-T cells is a viable approach for treating T-cell malignancies., Huang J, Alexey S, Li J, Jones T, Grande G, Douthit L, Xie J, Chen D, Wu X, Michael M, Xiao C, Zhao J, Xie X, Xie J, Chen XL, Fu G, Alexander G, Tzeng CM, 2019 Bioengineered Nanocage from HBc Protein for Combination Cancer Immunotherapy., Shan W, Zheng H, Fu G, Liu C, Li Z, Ye Y, Zhao J, Xu D, Sun L, Wang X, Chen XL, Bi S, Ren L, Fu G, 2019 Noninvasive photoacoustic and fluorescent tracking of optical dye labeled T cellular activities of diseased sites at new depth., Zheng S, Li H, Lai K, Chen M, Fu G, Liu WH, Fu G, Nie L, 2018 A critical role of periostin in B-cell acute lymphoblastic leukemia., Ma Z, Zhao X, Huang J, Jia X, Deng M, Cui D, Du Z, Fu G, Ouyang G, Xiao C, 2017 A miR-155-Peli1-c-Rel pathway controls the generation and function of T follicular helper cells., Liu WH, Kang SG, Huang Z, Wu CJ, Jin HY, Maine CJ, Liu Y, Shepherd J, Sabouri-Ghomi M, Gonzalez-Martin A, Xu S, Hoffmann A, Zheng Y, Lu LF, Xiao N, Fu G, Xiao C, 2016 Themis sets the signal threshold for positive and negative selection in T cell development., Fu G, Casas J, Rigaud S, Rybakin V, Lambolez F, Brzostek J, Hoerter JAH, Paster W, Acuto O, Cheroutre H, Sauer K, Gascoigne NR, 2013 Themis controls thymocyte selection through regulation of T cell antigen receptor-mediated signaling., Fu G, Vallée S, Rybakin V, McGuire MV, Ampudia J, Brockmeyer C, Salek M, Fallen PR, Hoerter JA, Munshi A, Huang YH, Hu J, Fox HS, Sauer K, Acuto O, Gascoigne NR, 2009 Protein Kinase C-η Controls CTLA-4-Mediated Regulatory T Cell Function., Kong KF, Fu G, Zhang Y, Yokosuka T, Casas J, Canonigo-Balancio A, Becart S, Kim G, Yates JR 3rd, Kronenberg M, Saito T, Gascoigne NR, Altman A, 2014 Protein Kinase C η Is Required for T Cell Activation and Homeostatic Proliferation., Fu G, Hu J, Niederberger-Magnenat N, Rybakin V, Casas J, Yachi PP, Feldstein S, Ma B, Hoerter JAH, Ampudia J, Rigaud S, Lambolez F, Gavin AL, Sauer K, Cheroutre H, Gascoigne NRJ, 2011 Multiplexed labeling of samples with cell tracking dyes facilitates rapid and accurate internally controlled calcium flux measurement by flow cytometry., Fu G, Gascoigne NR, 2009 Fine-tuning T cell receptor signaling to control T cell development., Fu G, Rybakin V, Brzostek J, Paster W, Acuto O, Gascoigne NR, 2014 Protein kinase C η, an emerging player in T cell biology., Fu G, Gascoigne NR, 2012

Areas of Focus

T cell function and molecular mechanisms in normal and disease states
Tumor immunity
Anti-infection immunity
Autoimmune diseases
Mass spectrometry flow cytometry and imaging techniques

Publications

Synthetic lethality of combined AT-101 with idarubicin in acute myeloid leukemia via blockade of DNA repair and activation of intrinsic apoptotic pathway., Yang Q, Chen K, Zhang L, Feng L, Fu G, Jiang S, Bi S, Lin C, Zhou Y, Zhao H, Chen XL, Fu G, Xu B, 2019
Unique CDR3 epitope targeting by CAR-T cells is a viable approach for treating T-cell malignancies., Huang J, Alexey S, Li J, Jones T, Grande G, Douthit L, Xie J, Chen D, Wu X, Michael M, Xiao C, Zhao J, Xie X, Xie J, Chen XL, Fu G, Alexander G, Tzeng CM, 2019
Bioengineered Nanocage from HBc Protein for Combination Cancer Immunotherapy., Shan W, Zheng H, Fu G, Liu C, Li Z, Ye Y, Zhao J, Xu D, Sun L, Wang X, Chen XL, Bi S, Ren L, Fu G, 2019
Noninvasive photoacoustic and fluorescent tracking of optical dye labeled T cellular activities of diseased sites at new depth., Zheng S, Li H, Lai K, Chen M, Fu G, Liu WH, Fu G, Nie L, 2018
A critical role of periostin in B-cell acute lymphoblastic leukemia., Ma Z, Zhao X, Huang J, Jia X, Deng M, Cui D, Du Z, Fu G, Ouyang G, Xiao C, 2017
A miR-155-Peli1-c-Rel pathway controls the generation and function of T follicular helper cells., Liu WH, Kang SG, Huang Z, Wu CJ, Jin HY, Maine CJ, Liu Y, Shepherd J, Sabouri-Ghomi M, Gonzalez-Martin A, Xu S, Hoffmann A, Zheng Y, Lu LF, Xiao N, Fu G, Xiao C, 2016
Themis sets the signal threshold for positive and negative selection in T cell development., Fu G, Casas J, Rigaud S, Rybakin V, Lambolez F, Brzostek J, Hoerter JAH, Paster W, Acuto O, Cheroutre H, Sauer K, Gascoigne NR, 2013
Themis controls thymocyte selection through regulation of T cell antigen receptor-mediated signaling., Fu G, Vallée S, Rybakin V, McGuire MV, Ampudia J, Brockmeyer C, Salek M, Fallen PR, Hoerter JA, Munshi A, Huang YH, Hu J, Fox HS, Sauer K, Acuto O, Gascoigne NR, 2009
Protein Kinase C-η Controls CTLA-4-Mediated Regulatory T Cell Function., Kong KF, Fu G, Zhang Y, Yokosuka T, Casas J, Canonigo-Balancio A, Becart S, Kim G, Yates JR 3rd, Kronenberg M, Saito T, Gascoigne NR, Altman A, 2014
Protein Kinase C η Is Required for T Cell Activation and Homeostatic Proliferation., Fu G, Hu J, Niederberger-Magnenat N, Rybakin V, Casas J, Yachi PP, Feldstein S, Ma B, Hoerter JAH, Ampudia J, Rigaud S, Lambolez F, Gavin AL, Sauer K, Cheroutre H, Gascoigne NRJ, 2011
Multiplexed labeling of samples with cell tracking dyes facilitates rapid and accurate internally controlled calcium flux measurement by flow cytometry., Fu G, Gascoigne NR, 2009
Fine-tuning T cell receptor signaling to control T cell development., Fu G, Rybakin V, Brzostek J, Paster W, Acuto O, Gascoigne NR, 2014
Protein kinase C η, an emerging player in T cell biology., Fu G, Gascoigne NR, 2012

T Cells Molecular Mechanisms Tumor Immunity Autoimmune Diseases Mass Spectrometry Flow Cytometry Immunotherapy Clinical Samples T Cell Development T Cell Activation

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