Professor | Guang-Hui Jin | Asia Growth Partners

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Name	Guang-Hui Jin
Contact Information	ghjin@xmu.edu.cn
Language ability	Chinese, English
Province	Fujian

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Name

Guang-Hui Jin

Contact Information

ghjin@xmu.edu.cn

Language ability

Chinese, English

Province

Fujian

University/Lab Affiliation and Title	Xiamen University
Faculty	Medical
Academic Background & Achievements	1994-1999: Bachelor of Medicine, Bethune Medical University 1999-2004: Doctor of Medicine, Jilin University, Bethune Medical Department Published over 30 SCI papers, including 18 as corresponding author in prestigious journals
Work Experience	2002-2004: Assistant Lecturer, Jilin University, Bethune Medical Department 2004-2006: Postdoctoral Researcher, Nanjing University, School of Life Sciences 2006-2011: Associate Professor, Xiamen University, School of Medicine 2011-2016: Professor, Xiamen University, School of Medicine 2016-present: Distinguished Professor, Xiamen University, School of Medicine
Awards	2016: Fujian Province Second Batch of Leading Talents in the Hundred-Thousand-Ten Thousand Project 2011: Fujian Province Outstanding Youth Fund 2011: Fujian Province New Century Excellent Talent Support Program 2008: Fujian Province Candidate for the New Century Hundred-Thousand-Ten Thousand Talent Project

University/Lab Affiliation and Title

Xiamen University

Faculty

Medical

Academic Background & Achievements

1994-1999: Bachelor of Medicine, Bethune Medical University
1999-2004: Doctor of Medicine, Jilin University, Bethune Medical Department
Published over 30 SCI papers, including 18 as corresponding author in prestigious journals

Work Experience

2002-2004: Assistant Lecturer, Jilin University, Bethune Medical Department
2004-2006: Postdoctoral Researcher, Nanjing University, School of Life Sciences
2006-2011: Associate Professor, Xiamen University, School of Medicine
2011-2016: Professor, Xiamen University, School of Medicine
2016-present: Distinguished Professor, Xiamen University, School of Medicine

Awards

2016: Fujian Province Second Batch of Leading Talents in the Hundred-Thousand-Ten Thousand Project
2011: Fujian Province Outstanding Youth Fund
2011: Fujian Province New Century Excellent Talent Support Program
2008: Fujian Province Candidate for the New Century Hundred-Thousand-Ten Thousand Talent Project

Areas of Focus	Epigenetics Chromatin Histone Remodeling Tumorigenesis Mechanisms
Publications	MEN1 deficiency leads to neuroendocrine differentiation of lung cancer and disrupts the DNA damage response., Huan Qiu, Bang-Ming Jin, Zhan-Feng Wang, Bin Xu, Qi-Fan Zheng, Li Zhang, Ling-Yu Zhu, Shuang Shi, Jun-Bo Yuan, Xiao Lin, Shu-Bin Gao, Guang-Hui Jin, 2020 Abnormal expression of menin predicts the pathogenesis and poor prognosis of adult gliomas., Zhan-Feng Wang, Xin-Yu Hong, Ling-Yu Zhu, Li Zhang, Huan Qiu, Yuan-Yuan Zhang, Ming-Cheng Yuan, Xing-Li Zhao, Qi-Fan Zheng, Guang-Hui Jin, 2019 Epigenetic alterations contribute to promoter activity of imprinting gene IGF2., Qi-Fan Zheng, Bin Xu, Hui-Min Wang, Li-Hong Ding, Jin-Yang Liu, Ling-Yu Zhu, Huan Qiu, Li Zhang, Guang-Yi Ni, Jing Ye, Shu-Bin Gao, Guang-Hui Jin, 2018 Enhancing chemotherapy sensitivity by targeting PcG via the ATM/p53 pathway., Gao SB, Li KL, Qiu H, Zhu LY, Pan CB, Zhao Y, Wei SH, Shi S, Jin GH, Xue LX, 2017 Reprogramming of histone methylation controls the differentiation of monocytes into macrophages., Zheng QF, Wang HM, Wang ZF, Liu JY, Zhang Q, Zhang L, Lu YH, You H, Jin GH, 2017 Male Men1 heterozygous mice exhibit fasting hyperglycemia in the early stage of MEN1., Gao Z, Zhang L, Xie W, Wang S, Bao X, Guo Y, Zhang H, Hu Q, Chen Y, Wang Z, Xue M, Jin G, 2016 An Epigenetic Pathway Regulates Sensitivity of Breast Cancer Cells to HER2 Inhibition via FOXO/c-Myc Axis., Matkar S, Sharma P, Gao S, Gurung B, Katona BW, Liao J, Muhammad AB, Kong XC, Wang L, Jin G, Dang CV, Hua X, 2015 Genetic alteration and misexpression of Polycomb group genes in hepatocellular carcinoma., Shu-Bin Gao, Shi-Long Sun, Qi-Lin Zheng, Li Zhang, Yuequan Zhu, Guang-Hui Jin, Li-Xiang Xue, 2015 EZH2 represses target genes through H3K27-dependent and H3K27-independent mechanisms in hepatocellular carcinoma., Gao SB, Zheng QF, Xu B, Pan CB, Li KL, Zhao Y, Zheng QL, Lin X, Xue LX, Jin GH, 2014 The functional and mechanistic relatedness of the EZH2 and menin in hepatocellular carcinoma., Gao SB, Xu B, Ding LH, Zheng Q, Zhang L, Zheng QF, Li SH, Feng ZJ, Wei J, Yin ZY, Hua X, Jin GH, 2014 Menin promotes hepatocellular carcinogenesis and epigenetically up-regulates Yap1 transcription., Xu B, Li SH, Zheng R, Gao SB, Ding LH, Yin ZY, Lin X, Feng ZJ, Zhang S, Wang XM, Jin GH, 2013 Menin Epigenetically Represses Hedgehog Signaling in MEN1 Tumor Syndrome., Gurung B, Feng Z, Iwamoto DV, Thiel A, Jin G, Fan CM, Ng JM, Curran T, Hua X, 2013 Interplay between menin and K-Ras in regulating lung adenocarcinoma., Wu Y, Feng ZJ, Gao SB, Matkar S, Xu B, Duan HB, Lin X, Li SH, Hua X, Jin GH, 2012 Menin represses malignant phenotypes of melanoma through regulating multiple pathways., Gao S, Feng ZJ, Xu B, Chen Y, Zheng HH, Yin P, Hua X, Jin GH, 2011 Tumor suppressor menin represses Paired box gene 2 expression via Wilms' tumor suppressor protein-Polycomb group complex., Xu B, Zeng DQ, Wu Y, Zheng R, Gu L, Lin X, Hua X, Jin GH, 2011 Lung cancer cell migration is regulated via repressing growth factor PTN/RPTP beta/zeta signaling by menin., Feng ZJ, Gao SB, Wu Y, Xu XF, Hua X, Jin GH, 2010 Suppression of lung adenocarcinoma through menin and polycomb gene-mediated repression of growth factor pleiotrophin., Gao SB, Feng ZJ, Xu B, Wu Y, Yin P, Yang Y, Hua X, GH Jin, 2009

Areas of Focus

Epigenetics
Chromatin Histone Remodeling
Tumorigenesis Mechanisms

Publications

MEN1 deficiency leads to neuroendocrine differentiation of lung cancer and disrupts the DNA damage response., Huan Qiu, Bang-Ming Jin, Zhan-Feng Wang, Bin Xu, Qi-Fan Zheng, Li Zhang, Ling-Yu Zhu, Shuang Shi, Jun-Bo Yuan, Xiao Lin, Shu-Bin Gao, Guang-Hui Jin, 2020
Abnormal expression of menin predicts the pathogenesis and poor prognosis of adult gliomas., Zhan-Feng Wang, Xin-Yu Hong, Ling-Yu Zhu, Li Zhang, Huan Qiu, Yuan-Yuan Zhang, Ming-Cheng Yuan, Xing-Li Zhao, Qi-Fan Zheng, Guang-Hui Jin, 2019
Epigenetic alterations contribute to promoter activity of imprinting gene IGF2., Qi-Fan Zheng, Bin Xu, Hui-Min Wang, Li-Hong Ding, Jin-Yang Liu, Ling-Yu Zhu, Huan Qiu, Li Zhang, Guang-Yi Ni, Jing Ye, Shu-Bin Gao, Guang-Hui Jin, 2018
Enhancing chemotherapy sensitivity by targeting PcG via the ATM/p53 pathway., Gao SB, Li KL, Qiu H, Zhu LY, Pan CB, Zhao Y, Wei SH, Shi S, Jin GH, Xue LX, 2017
Reprogramming of histone methylation controls the differentiation of monocytes into macrophages., Zheng QF, Wang HM, Wang ZF, Liu JY, Zhang Q, Zhang L, Lu YH, You H, Jin GH, 2017
Male Men1 heterozygous mice exhibit fasting hyperglycemia in the early stage of MEN1., Gao Z, Zhang L, Xie W, Wang S, Bao X, Guo Y, Zhang H, Hu Q, Chen Y, Wang Z, Xue M, Jin G, 2016
An Epigenetic Pathway Regulates Sensitivity of Breast Cancer Cells to HER2 Inhibition via FOXO/c-Myc Axis., Matkar S, Sharma P, Gao S, Gurung B, Katona BW, Liao J, Muhammad AB, Kong XC, Wang L, Jin G, Dang CV, Hua X, 2015
Genetic alteration and misexpression of Polycomb group genes in hepatocellular carcinoma., Shu-Bin Gao, Shi-Long Sun, Qi-Lin Zheng, Li Zhang, Yuequan Zhu, Guang-Hui Jin, Li-Xiang Xue, 2015
EZH2 represses target genes through H3K27-dependent and H3K27-independent mechanisms in hepatocellular carcinoma., Gao SB, Zheng QF, Xu B, Pan CB, Li KL, Zhao Y, Zheng QL, Lin X, Xue LX, Jin GH, 2014
The functional and mechanistic relatedness of the EZH2 and menin in hepatocellular carcinoma., Gao SB, Xu B, Ding LH, Zheng Q, Zhang L, Zheng QF, Li SH, Feng ZJ, Wei J, Yin ZY, Hua X, Jin GH, 2014
Menin promotes hepatocellular carcinogenesis and epigenetically up-regulates Yap1 transcription., Xu B, Li SH, Zheng R, Gao SB, Ding LH, Yin ZY, Lin X, Feng ZJ, Zhang S, Wang XM, Jin GH, 2013
Menin Epigenetically Represses Hedgehog Signaling in MEN1 Tumor Syndrome., Gurung B, Feng Z, Iwamoto DV, Thiel A, Jin G, Fan CM, Ng JM, Curran T, Hua X, 2013
Interplay between menin and K-Ras in regulating lung adenocarcinoma., Wu Y, Feng ZJ, Gao SB, Matkar S, Xu B, Duan HB, Lin X, Li SH, Hua X, Jin GH, 2012
Menin represses malignant phenotypes of melanoma through regulating multiple pathways., Gao S, Feng ZJ, Xu B, Chen Y, Zheng HH, Yin P, Hua X, Jin GH, 2011
Tumor suppressor menin represses Paired box gene 2 expression via Wilms' tumor suppressor protein-Polycomb group complex., Xu B, Zeng DQ, Wu Y, Zheng R, Gu L, Lin X, Hua X, Jin GH, 2011
Lung cancer cell migration is regulated via repressing growth factor PTN/RPTP beta/zeta signaling by menin., Feng ZJ, Gao SB, Wu Y, Xu XF, Hua X, Jin GH, 2010
Suppression of lung adenocarcinoma through menin and polycomb gene-mediated repression of growth factor pleiotrophin., Gao SB, Feng ZJ, Xu B, Wu Y, Yin P, Yang Y, Hua X, GH Jin, 2009

Epigenetics Histone Chromatin Remodeling Tumorigenesis Mechanisms Enzymes Biological Functions Cancer Regulation

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