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Ying Chen
Medical School
Xiamen University
Fujian
Language: English, Chinese
Myelination
Glial Cells
Molecular Mechanisms
Epigenetics
Chromatin Remodeling
G-Protein Coupled Receptors
Oligodendrocytes
Schwann Cells
Cell Differentiation
Neuroglial Regeneration
Areas of Focus
- Development and molecular mechanisms of myelinating glial cells and related diseases
Work Experience
- 2007-2012 - Postdoctoral Researcher at Southwestern Medical Center
Academic Background & Achievements
- 2006 - PhD in Immunology and Microbiology: Rush University
Publications
- A GPR17-cAMP-Lactate Signaling Axis in Oligodendrocytes Regulates Whole-Body Metabolism., Ou Z, Ma Y, Sun Y, Zheng G, Wang S, Xing R, Chen X, Han Y, Wang J, Lu QR, Zhao TJ, Chen Y., 2019
- Olig2-Targeted G-Protein-Coupled Receptor Gpr17 Regulates Oligodendrocyte Survival in Response to Lysolecithin-Induced Demyelination., Ou Z, Sun Y, Lin L, You N, Liu X, Li H, Ma Y, Cao L, Han Y, Liu M, Deng Y, Yao L, Lu QR, Chen Y., 2016
- Olig2 Targets Chromatin Remodelers To Enhancers To Initiate Oligodendrocyte Differentiation., Yu Y*, Y. Chen*, B. Kim*, H. Wang, C. Zhao, X. He, L. Liu, W. Liu, L. M. N. Wu, M. Mao, J. R. Chan, J. Wu and Q. R. Lu, 2013
- HDAC-mediated Deacetylation of NF-κB is Critical for Schwann cell Myelination., Ying Chen, Haibo Wang, Sung Ok Yoon, Xiaomei Xu, Michael Hottiger, Haesun Kim, Eric N. Olson, and Q. Richard Lu., 2011
- The oligodendrocyte-specific G-protein coupled receptor GPR17 is a cell intrinsic timer of myelination., Chen, Y. H. Wu, S. Wang, H. Koito, J. Li, J. Hoang, F. Ye, S. S. Escobar, A. Gow, H. A. Arnett, B. D. Trapp, N. J. Karandikar, J. Hsieh and Q. R. Lu., 2009
- The basic helix-loop-helix transcription factor olig2 is critical for reactive astrocyte proliferation after cortical injury., Chen Y, Miles DK, Hoang T, Shi J, Hurlock E, Kernie SG, Lu QR., 2008
