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陈颖
Medical School
厦门大学
福建
Language: 英语, 中文
髓鞘形成
胶质细胞
分子机制
表观遗传学
染色质重塑
G蛋白偶联受体
少突胶质细胞
雪旺氏细胞
细胞分化
神经胶质再生
Areas of Focus
- 髓鞘形成胶质细胞的发育及相关疾病的分子机制
Work Experience
- 2007年至2012年 - 西南医学中心博士后研究员
Academic Background & Achievements
- 2006年 - 免疫与微生物学博士：美国Rush大学
Publications
- A GPR17-cAMP-Lactate Signaling Axis in Oligodendrocytes Regulates Whole-Body Metabolism., Ou Z, Ma Y, Sun Y, Zheng G, Wang S, Xing R, Chen X, Han Y, Wang J, Lu QR, Zhao TJ, Chen Y., 2019
- Olig2-Targeted G-Protein-Coupled Receptor Gpr17 Regulates Oligodendrocyte Survival in Response to Lysolecithin-Induced Demyelination., Ou Z, Sun Y, Lin L, You N, Liu X, Li H, Ma Y, Cao L, Han Y, Liu M, Deng Y, Yao L, Lu QR, Chen Y., 2016
- Olig2 Targets Chromatin Remodelers To Enhancers To Initiate Oligodendrocyte Differentiation., Yu Y*, Y. Chen*, B. Kim*, H. Wang, C. Zhao, X. He, L. Liu, W. Liu, L. M. N. Wu, M. Mao, J. R. Chan, J. Wu and Q. R. Lu, 2013
- HDAC-mediated Deacetylation of NF-κB is Critical for Schwann cell Myelination., Ying Chen, Haibo Wang, Sung Ok Yoon, Xiaomei Xu, Michael Hottiger, Haesun Kim, Eric N. Olson, and Q. Richard Lu., 2011
- The oligodendrocyte-specific G-protein coupled receptor GPR17 is a cell intrinsic timer of myelination., Chen, Y. H. Wu, S. Wang, H. Koito, J. Li, J. Hoang, F. Ye, S. S. Escobar, A. Gow, H. A. Arnett, B. D. Trapp, N. J. Karandikar, J. Hsieh and Q. R. Lu., 2009
- The basic helix-loop-helix transcription factor olig2 is critical for reactive astrocyte proliferation after cortical injury., Chen Y, Miles DK, Hoang T, Shi J, Hurlock E, Kernie SG, Lu QR., 2008
