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Yufen Zhao
Medical School
Xiamen University
Fujian
Language: English, Chinese
Organic Chemistry
Phosphorus
Life Origin
Medicinal
Chemical Biology
Synthesis
Kinase
Mass Spectrometry
Peptide
Protein
Areas of Focus
- Life Organic Chemistry
- Organic Phosphorus Chemistry
- Origin of Life
- Medicinal Chemistry
- Chemical Biology
Academic Background & Achievements
- 1975 - Ph.D.: State University of New York at Stony Brook
- Bachelor's: National Tsing Hua University, Taiwan
- Postdoctoral: State University of New York at Stony Brook
- Academician of the Chinese Academy of Sciences
Publications
- A universal and multiplex kinase assay using γ-[18O4]-ATP, Fu, Chuan; Zheng, Xueyun; Jiang, Yao; Liu, Yan; Xu, Pengxiang; Zeng, Zhiping; Liu, Rihe; Zhao, Yufen, 2013
- Copper-Catalyzed Synthesis of α-Hydroxy Phosphonates from H-Phosphonates and Alcohols or Ethers, Zhao, Zengxiang; Xue, Wanhua; Gao, Yuxing; Tang, Guo; Zhao, Yufen, 2013
- Nickel(II)-magnesium-catalyzed cross-coupling of 1,1-dibromo-1-alkenes with diphenylphosphine oxide: one-pot synthesis of (E)-1-alkenylphosphine oxides or bisphosphine oxides, Liu, Liu; Wang, Yulei; Zeng, Zhiping; Xu, Pengxiang; Gao, Yuxing; Yin, Yingwu; Zhao, Yufen, 2013
- Stable Isotope N-Phosphorylation Labeling for Peptide de Novo Sequencing and Protein Quantification Based on Organic Phosphorus Chemistry, Gao, Xiang; Wu, Hanzhi; Lee, Kim-Chung; Liu, Hongxia; Zhao, Yufen; Cai, Zongwei; Jiang, Yuyang, 2012
- Suppression of matrix ions by N-phosphorylation labeling using matrix-assisted laser desorption-ionization time-of-flight mass spectrometry, Gao, Xiang; Tang, Zhi; Lu, Minghua; Liu, Hongxia; Jiang, Yuyang; Zhao, Yufen; Cai, Zongwei, 2012
- An isotope (18O, 15N, and 2H) technique to investigate the metal ion interactions between the phosphoryl group and amino acid side chains by electrospray ionization mass spectrometry, Gao, Xiang; Hu, Xiaomei; Zhu, Jun; Zeng, Zhiping; Han, Daxiong; Tang, Guo; Huang, Xiantong; Xu, Pengxiang; Zhao, Yufen, 2011
- Fast separation of antiviral nucleoside phosphoramidate and H-phosphonate diastereoisomers by reversed-phase liquid chromatography, Gao, Xiang; Chen, Weizhu; Zhu, Gangtian; Yi, Ruizao; Wu, Zhen; Xu, Pengxiang; Zhao, Yufen, 2011
- Intermolecular phosphoryl transfer of N-phosphoryl amino acids, Gao, Xiang; Deng, Honggui; Tang, Guo; Liu, Yan; Xu, Pengxiang; Zhao, Yufen, 2011
- Stereospecific Coupling of H-Phosphinates and Secondary Phosphine Oxides with Amines and Alcohols: A General Method for the Preparation of Optically Active Organophosphorus Acid Derivatives, G. Wang, R.-W. Shen, Q. Xu, Goto Midori, Y.-F. Zhao and L.-B. Han, 2010
- Selective P-P and P-O-P Bond Formations through Copper-Catalyzed Aerobic Oxidative Dehydrogenative Couplings of H-Phosphonates, Y.-B. Zhou, S.-F. Yin, Y.-X. Gao, Y.-F. Zhao, Midori Goto, and L.-B. Han, 2010
- Genome wide exploration of the origin and evolution of amino acids, X.-X. Liu, J.-X. Zhang, F. Ni, X. Dong, B.-C. Han, D.-X. Han, Z.-L. Ji, Y.-F. Zhao, 2010
- Copper-Catalyzed Aerobic Oxidative Coupling of Terminal Alkynes with H-Phosphonates Leading to Alkynylphosphonates, Y.-X. Gao, G. Wang, L. Chen, P.-X. Xu, Y.-F. Zhao, Y.-B. Zhou, and L.-B. Han, 2009
- N-phosphorylation of amino acids by trimetaphosphate in aqueous solution—learning from prebiotic synthesis, F. Ni, S.-T. Sun, C. Huang and Y.-F. Zhao, 2009
- On the Electrophilicity of cyclic acylphosphoramidates (CAPAs) postulated as intermediates, F. Ni, X. Gao, Z.-X. Zhao, C. Huang, and Y.-F. Zhao, 2009
- Chirality at phosphorus in pentacoordinate spirophosphoranes: stereochemistry by X-ray structure and spectroscopic analysis, J.-B. Hou, H. Zhang, J.-N. Guo, Y. Liu, P.-X. Xu, Y.-F. Zhao and G. M. Blackburn, 2009
- Negative ion electrospray ionization mass spectrometry of nucleoside phosphoramidate monoesters: elucidation of novel rearrangement mechanisms by multistage mass spectrometry incorporating in-source deuterium labeling, P.-X. Xu, A.-F. Hu, D. Hu, X. Gao, Y.-F. Zhao, 2008
- Alpha-amino acid behaves differently from beta- or gamma-amino acids as treated by trimetaphosphate, X. Gao, Y. Liu, P.-X. Xu, Y.-F. Zhao, 2008
- DNA cleavage function of seryl-histidine dipeptide and its application, Y. Ma, X. Chen, M. Sun, R. Wan, C.-J. Zhu, Y.-M. Li, Y.-F. Zhao, 2008
- Analysis of the phosphoryl transfer mechanism of c-amp dependent protein kinase (pka) by penta-coodinate phosphoric transition state theory, F. Ni, W. Li, Y. Li, Y.-F. Zhao, 2005
Awards
- International Abzov Award
- Second and Third Prizes of the Chinese Academy of Sciences for Scientific and Technological Progress
- Second and Third Prizes of the Ministry of Education for Scientific and Technological Progress
- China Youth Scientist Award
- Second New Century Female Inventor
