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Kun Shen
Medical School
Wuhan University
Hubei
Language: Chinese, English
Organic Chemistry
Medicinal Chemistry
Chemical Biology
Synthesis
Chirality
Natural Products
Drug Development
Drug Design
Molecular Mechanisms
Asymmetric Synthesis
Areas of Focus
- Organic Chemistry
- Medicinal Chemistry
- Chemical Biology
- Synthetic Methodology
- Chiral Drugs and Natural Product Synthesis
- Innovative Drug Research and Development
- Drug Molecular Mechanism Studies
Work Experience
- 2018.9 – Present Associate Researcher, School of Pharmaceutical Sciences, Wuhan University
- 2013.8 – 2018.7 Postdoctoral Researcher, Department of Chemistry, Duke University, USA
Academic Background & Achievements
- 2008 – 2013 PhD in Organic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences
- 2004 – 2008 Bachelor of Science in Chemistry and Molecular Sciences, Wuhan University
Publications
- Copper-Catalyzed Alkene Aminoazidation as a Rapid Entry to 1,2-Diamines and Installation of an Azide Reporter onto Azahetereocycles, Shen, K.; Wang, Q.*, 2017
- Diazirines as Potential Universal Molecular MRI Tags: Probing the Requirements for Efficient and Long-Lived SABRE-Induced Hyperpolarization, Shen, K.; Logan, A. W. J.; Colell, J. F. P.; Bae, J.; Ortiz, G. X.; Theis, T.; Warren, W. S.; Malcolmson, S. J.; Wang, Q.*, 2017
- Copper-Catalyzed Aminoalkynylation of Alkenes with Hypervalent Iodine Reagents, Shen, K.; Wang, Q.*, 2017
- Copper-Catalyzed Amino Lactonization and Amino Oxygenation of Alkenes Using O-Benzoylhydroxylamines, Hemric, B. N.; Shen, K.; Wang, Q.*, 2016
- Copper-catalyzed Aminotrifluoromethylation of Alkenes: A Facile Synthesis of CF3-Containing Lactams, Shen, K.; Wang, Q.*, 2016
- Copper-Catalyzed Diamination of Unactivated Alkenes with Hydroxylamines, Shen, K.; Wang, Q.*, 2015
- Cationic Pd(II)-Catalyzed Arylative Cyclization of 1,6-Enynes with Arylboronic Acids, Shen, K.; Han, X.; Lu, X.*; Hu, Z., 2017
- Cationic Pd(II)-Catalyzed Cyclization of N-tosyl-aniline Tethered Alkynyl Ketones Initiated by Hydropalladation of Alkynes: A Facile Way to 1,2-Dihydro- or 1,2,3,4-Tetrahydroquinoline Derivatives, Shen, K.; Han, X.; Xia, G.; Lu, X.*, 2015
- Cationic Palladium(II)-Catalyzed Reductive Cyclization of Alkyne-Tethered Ketones or Aldehydes Using Ethanol as Hydrogen Source, Shen, K.; Han, X.; Lu, X.*, 2013
- Cationic Palladium(II)-Catalyzed Highly Enantioselective Arylative Cyclization of Alkyne-Tethered Enals or Enones Initiated by Carbopalladation of Alkynes with Arylboronic Acids, Shen, K.; Han, X.; Lu, X.*, 2012
