Professor | Xian Zhang | Asia Growth Partners

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Name	Xian Zhang
Contact Information	xianzhang@xmu.edu.cn
Language ability	Chinese, English
Province	Fujian

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Name

Xian Zhang

Contact Information

xianzhang@xmu.edu.cn

Language ability

Chinese, English

Province

Fujian

University/Lab Affiliation and Title	Xiamen University
Faculty	Medical
Academic Background & Achievements	2000-2004 Bachelor of Science in Life Sciences: Xiamen University 2004-2009 Doctor of Science in Cell Biology: Xiamen University
Work Experience	2009-2011 - Xiamen University Biomedical Research Institute - Assistant Professor 2011-Present - Xiamen University School of Medicine - Assistant Professor

University/Lab Affiliation and Title

Xiamen University

Faculty

Medical

Academic Background & Achievements

2000-2004 Bachelor of Science in Life Sciences: Xiamen University
2004-2009 Doctor of Science in Cell Biology: Xiamen University

Work Experience

2009-2011 - Xiamen University Biomedical Research Institute - Assistant Professor
2011-Present - Xiamen University School of Medicine - Assistant Professor

Areas of Focus	Molecular pathogenesis of neurodegenerative diseases Alzheimer's disease research
Publications	SNX27 Deletion Causes Hydrocephalus by Impairing Ependymal Cell Differentiation and Ciliogenesis, Wang X, Zhou Y, Wang J, Tseng IC, Huang T, Zhao Y, Zheng Q, Gao Y, Luo H, Zhang X, Bu G, Hong W, Xu H, 2016 The γ-secretase complex: from structure to function, Zhang X, Li Y, Xu H, Zhang YW, 2014 Appoptosin is a novel pro-apoptotic protein and mediates cell death in neurodegeneration, Zhang H, Zhang YW, Chen Y, Huang X, Zhou F, Wang W, Xian B, Zhang X, Masliah E, Chen Q, Han JD, Bu G, Reed JC, Liao FF, Chen YG, Xu H, 2012 M1 muscarinic acetylcholine receptor interacts with BACE1 and regulates its proteosomal degradation, Jiang S, Wang Y, Ma Q, Hou H, Zhang X, Zhang Y-w, 2012 Sorting nexin 12 interacts with BACE1 and regulates BACE1-mediated APP processing, Zhao Y, Wang Y, Yang J, Wang X, Zhao Y, Zhang X, Zhang YW, 2012 CutA divalent cation tolerance homolog (E. coli) (CUTA) regulates β-cleavage of β-amyloid precursor protein (APP) through interacting with β-Site APP cleaving protein 1 (BACE1), Zhao Y, Wang Y, Hu J, Zhang X, Zhang YW, 2012 Hypoxia inducible factor 1a (HIF-1a)-mediated hypoxia increases BACE1 expression and β-amyloid generation, Zhang X, Zhou K, Wang R, Cui J, Lipton SA, Liao FF, Xu H, Zhang Y-w, 2007 Transcriptional regulation of APH-1A and increased γ-secretase cleavage of APP and Notch by HIF-1 and hypoxia, Wang R, Zhang Y-w, Zhang X, Liu R, Zhang X, Hong SH, Xia K, Xia J, Zhang Z, Xu H, 2006 Transcriptional regulation of PEN-2, a key component of the γ-secretase complex, by CREB, Wang R, Zhang Y-W, Sun P, Liu R, Zhang X, Zhang X, Xi JH, Xu H, Zhang Z, 2006

Areas of Focus

Molecular pathogenesis of neurodegenerative diseases
Alzheimer's disease research

Publications

SNX27 Deletion Causes Hydrocephalus by Impairing Ependymal Cell Differentiation and Ciliogenesis, Wang X, Zhou Y, Wang J, Tseng IC, Huang T, Zhao Y, Zheng Q, Gao Y, Luo H, Zhang X, Bu G, Hong W, Xu H, 2016
The γ-secretase complex: from structure to function, Zhang X, Li Y, Xu H, Zhang YW, 2014
Appoptosin is a novel pro-apoptotic protein and mediates cell death in neurodegeneration, Zhang H, Zhang YW, Chen Y, Huang X, Zhou F, Wang W, Xian B, Zhang X, Masliah E, Chen Q, Han JD, Bu G, Reed JC, Liao FF, Chen YG, Xu H, 2012
M1 muscarinic acetylcholine receptor interacts with BACE1 and regulates its proteosomal degradation, Jiang S, Wang Y, Ma Q, Hou H, Zhang X, Zhang Y-w, 2012
Sorting nexin 12 interacts with BACE1 and regulates BACE1-mediated APP processing, Zhao Y, Wang Y, Yang J, Wang X, Zhao Y, Zhang X, Zhang YW, 2012
CutA divalent cation tolerance homolog (E. coli) (CUTA) regulates β-cleavage of β-amyloid precursor protein (APP) through interacting with β-Site APP cleaving protein 1 (BACE1), Zhao Y, Wang Y, Hu J, Zhang X, Zhang YW, 2012
Hypoxia inducible factor 1a (HIF-1a)-mediated hypoxia increases BACE1 expression and β-amyloid generation, Zhang X, Zhou K, Wang R, Cui J, Lipton SA, Liao FF, Xu H, Zhang Y-w, 2007
Transcriptional regulation of APH-1A and increased γ-secretase cleavage of APP and Notch by HIF-1 and hypoxia, Wang R, Zhang Y-w, Zhang X, Liu R, Zhang X, Hong SH, Xia K, Xia J, Zhang Z, Xu H, 2006
Transcriptional regulation of PEN-2, a key component of the γ-secretase complex, by CREB, Wang R, Zhang Y-W, Sun P, Liu R, Zhang X, Zhang X, Xi JH, Xu H, Zhang Z, 2006

Neurodegeneration Molecular Mechanisms Alzheimer'S Disease Β-Amyloid Protein Factors Cellular Cascades Molecular Cascades Aβ Generation Aβ Transport Aβ Degradation

Fang Marong - Zhejiang University

Qingqing Tao - Zhejiang University

Gao Yue - Xiamen University

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