Professor | Jun Yao | Asia Growth Partners

Name	Jun Yao
Contact Information	jyao@mail.tsinghua.edu.cn
Language ability	English, Chinese
Province	Beijing

Name

Jun Yao

Contact Information

jyao@mail.tsinghua.edu.cn

Language ability

English, Chinese

Province

Beijing

University/Lab Affiliation and Title	Tsinghua University
Faculty	Life Sciences
Academic Background & Achievements	1999 Bachelor: Nanjing University, Department of Biological Sciences and Technology 2001 Master: Nanjing University, Department of Biological Sciences and Technology 2007 PhD: Pennsylvania State University
Work Experience	2007-2011 - Howard Hughes Medical Institute, University of Wisconsin - Postdoctoral Research Associate 2011-2013 - Salk Institute for Biological Studies - Research Associate 2013-present - Tsinghua University, School of Life Sciences - Assistant Professor, Associate Professor

University/Lab Affiliation and Title

Tsinghua University

Faculty

Life Sciences

Academic Background & Achievements

1999 Bachelor: Nanjing University, Department of Biological Sciences and Technology
2001 Master: Nanjing University, Department of Biological Sciences and Technology
2007 PhD: Pennsylvania State University

Work Experience

2007-2011 - Howard Hughes Medical Institute, University of Wisconsin - Postdoctoral Research Associate
2011-2013 - Salk Institute for Biological Studies - Research Associate
2013-present - Tsinghua University, School of Life Sciences - Assistant Professor, Associate Professor

Areas of Focus	Genetics, molecular and neural circuit dimensions to elucidate the pathogenesis of affective disorders (bipolar disorder and depression)
Publications	miR-218-2 regulates cognitive functions in the hippocampus through C3-dependent modulation of synaptic vesicle release, Lu SY, Fu CL, Liang L, Yang B, Shen W, Wang QW, Chen Y, Chen YF, Liu YN, Zhu L, Zhao J, Shi W, Mi S, Yao J, 2021 Synaptotagmin-1 interacts with PI(4,5)P2 to initiate synaptic vesicle docking in hippocampal neurons, Chen Y, Wang YH, Zheng Y, Li M, Wang B, Wang QW, Fu CL, Liu YN, Li X, Yao J, 2021 Synaptotagmin-7 deficiency induces mania-like behavioral abnormalities through attenuating GluN2B activity, Wang QW, Lu SY, Liu YN, Chen Y, Wei H, Shen W, Chen YF, Fu CL, Wang YH, Dai A, Huang X, Gage FH, Xu Q, Yao J, 2020 Synaptotagmin-7 is a key factor for bipolar-like behavioral abnormalities in mice, Shen W, Wang QW, Liu YN, et al., Gage FH, and Yao J, 2020 CRISPR interference-based specific and efficient gene inactivation in the brain, Zheng Y, Shen W, Zhang J, Yang B, Liu YN, Qi H, Yu X, Lu SY, Chen Y, Xu YZ, Li Y, Gage FH, Mi S, and Yao J, 2018 Application of induced pluripotent stem cells to understand neurobiological basis of bipolar disorder and schizophrenia, Liu, Y.N., Lu, S.Y., and Yao, J., 2017 Differential Responses to Lithium in Hyperexcitable Neurons from Bipolar Patients, Mertens J, Wang QW, Kim Y, Yu DX, Pham S, Yang B, Zheng Y, Diffenderfer KE, Zhang J, Soltani S, Eames TJ, Schafer ST, Boyer L, Marchetto MC, Nurnberger JI, Calabrese JR, Ødegaard KJ, McCarthy MJ, Zandi PP, PBDS, Mi S, Brennand KJ, Kelsoe JR, Gage FH, Yao J, 2015

Areas of Focus

Genetics, molecular and neural circuit dimensions to elucidate the pathogenesis of affective disorders (bipolar disorder and depression)

Publications

miR-218-2 regulates cognitive functions in the hippocampus through C3-dependent modulation of synaptic vesicle release, Lu SY, Fu CL, Liang L, Yang B, Shen W, Wang QW, Chen Y, Chen YF, Liu YN, Zhu L, Zhao J, Shi W, Mi S, Yao J, 2021
Synaptotagmin-1 interacts with PI(4,5)P2 to initiate synaptic vesicle docking in hippocampal neurons, Chen Y, Wang YH, Zheng Y, Li M, Wang B, Wang QW, Fu CL, Liu YN, Li X, Yao J, 2021
Synaptotagmin-7 deficiency induces mania-like behavioral abnormalities through attenuating GluN2B activity, Wang QW, Lu SY, Liu YN, Chen Y, Wei H, Shen W, Chen YF, Fu CL, Wang YH, Dai A, Huang X, Gage FH, Xu Q, Yao J, 2020
Synaptotagmin-7 is a key factor for bipolar-like behavioral abnormalities in mice, Shen W, Wang QW, Liu YN, et al., Gage FH, and Yao J, 2020
CRISPR interference-based specific and efficient gene inactivation in the brain, Zheng Y, Shen W, Zhang J, Yang B, Liu YN, Qi H, Yu X, Lu SY, Chen Y, Xu YZ, Li Y, Gage FH, Mi S, and Yao J, 2018
Application of induced pluripotent stem cells to understand neurobiological basis of bipolar disorder and schizophrenia, Liu, Y.N., Lu, S.Y., and Yao, J., 2017
Differential Responses to Lithium in Hyperexcitable Neurons from Bipolar Patients, Mertens J, Wang QW, Kim Y, Yu DX, Pham S, Yang B, Zheng Y, Diffenderfer KE, Zhang J, Soltani S, Eames TJ, Schafer ST, Boyer L, Marchetto MC, Nurnberger JI, Calabrese JR, Ødegaard KJ, McCarthy MJ, Zandi PP, PBDS, Mi S, Brennand KJ, Kelsoe JR, Gage FH, Yao J, 2015

Genetics Molecular Neural Circuits Pathogenesis Affective Disorders Bipolar Disorder Depression Ipsc 3D Brain Models Mouse Models

Jun Yao - Tsinghua University

Chang Hong - University of Chinese Academy of Sciences

Shiwu Li - University of Chinese Academy of Sciences

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