Areas of Focus
- Genetics, molecular and neural circuit dimensions to elucidate the pathogenesis of affective disorders (bipolar disorder and depression)
Work Experience
- 2007-2011 - Howard Hughes Medical Institute, University of Wisconsin - Postdoctoral Research Associate
- 2011-2013 - Salk Institute for Biological Studies - Research Associate
- 2013-present - Tsinghua University, School of Life Sciences - Assistant Professor, Associate Professor
Academic Background & Achievements
- 1999 Bachelor: Nanjing University, Department of Biological Sciences and Technology
- 2001 Master: Nanjing University, Department of Biological Sciences and Technology
- 2007 PhD: Pennsylvania State University
Publications
- miR-218-2 regulates cognitive functions in the hippocampus through C3-dependent modulation of synaptic vesicle release, Lu SY, Fu CL, Liang L, Yang B, Shen W, Wang QW, Chen Y, Chen YF, Liu YN, Zhu L, Zhao J, Shi W, Mi S, Yao J, 2021
- Synaptotagmin-1 interacts with PI(4,5)P2 to initiate synaptic vesicle docking in hippocampal neurons, Chen Y, Wang YH, Zheng Y, Li M, Wang B, Wang QW, Fu CL, Liu YN, Li X, Yao J, 2021
- Synaptotagmin-7 deficiency induces mania-like behavioral abnormalities through attenuating GluN2B activity, Wang QW, Lu SY, Liu YN, Chen Y, Wei H, Shen W, Chen YF, Fu CL, Wang YH, Dai A, Huang X, Gage FH, Xu Q, Yao J, 2020
- Synaptotagmin-7 is a key factor for bipolar-like behavioral abnormalities in mice, Shen W, Wang QW, Liu YN, et al., Gage FH, and Yao J, 2020
- CRISPR interference-based specific and efficient gene inactivation in the brain, Zheng Y, Shen W, Zhang J, Yang B, Liu YN, Qi H, Yu X, Lu SY, Chen Y, Xu YZ, Li Y, Gage FH, Mi S, and Yao J, 2018
- Application of induced pluripotent stem cells to understand neurobiological basis of bipolar disorder and schizophrenia, Liu, Y.N., Lu, S.Y., and Yao, J., 2017
- Differential Responses to Lithium in Hyperexcitable Neurons from Bipolar Patients, Mertens J, Wang QW, Kim Y, Yu DX, Pham S, Yang B, Zheng Y, Diffenderfer KE, Zhang J, Soltani S, Eames TJ, Schafer ST, Boyer L, Marchetto MC, Nurnberger JI, Calabrese JR, Ødegaard KJ, McCarthy MJ, Zandi PP, PBDS, Mi S, Brennand KJ, Kelsoe JR, Gage FH, Yao J, 2015
