Professor | Chang Hong | Asia Growth Partners

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Name	Chang Hong
Contact Information	changhong@mail.kiz.ac.cn
Language ability	Chinese, English
Province	Yunnan

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Name

Chang Hong

Contact Information

changhong@mail.kiz.ac.cn

Language ability

Chinese, English

Province

Yunnan

University/Lab Affiliation and Title	University of Chinese Academy of Sciences
Faculty	Life Sciences
Academic Background & Achievements	2008-09--2011-06 PhD in Science: University of Chinese Academy of Sciences 2005-09--2008-06 MSc in Science: Yunnan University 2001-09--2005-06 BSc in Science: Yunnan University
Work Experience	2022-01~2022-06 - Kunming Institute of Zoology - Researcher 2017-01~2021-12 - Kunming Institute of Zoology - Associate Researcher 2016-07~2017-01 - Kunming Institute of Zoology - Assistant Researcher 2014-01~2016-06 - Mitchell Cancer Institute, University of South Alabama - Postdoctoral Researcher 2012-07~2013-09 - Kunming Institute of Zoology - Assistant Researcher 2011-07~2012-06 - Kunming Institute of Zoology - Research Intern

University/Lab Affiliation and Title

University of Chinese Academy of Sciences

Faculty

Life Sciences

Academic Background & Achievements

2008-09--2011-06 PhD in Science: University of Chinese Academy of Sciences
2005-09--2008-06 MSc in Science: Yunnan University
2001-09--2005-06 BSc in Science: Yunnan University

Work Experience

2022-01~2022-06 - Kunming Institute of Zoology - Researcher
2017-01~2021-12 - Kunming Institute of Zoology - Associate Researcher
2016-07~2017-01 - Kunming Institute of Zoology - Assistant Researcher
2014-01~2016-06 - Mitchell Cancer Institute, University of South Alabama - Postdoctoral Researcher
2012-07~2013-09 - Kunming Institute of Zoology - Assistant Researcher
2011-07~2012-06 - Kunming Institute of Zoology - Research Intern

Areas of Focus	Functional Genomics of Psychiatric Disorders
Publications	Reduced Vrk2 expression is associated with higher risk of depression in humans and mediates depressive-like behaviors in mice, Chang Hong, 2023 Identification of a psychiatric risk gene NISCH at 3p21.1 GWAS locus mediating dendritic spine morphogenesis and cognitive function, Chang Hong, 2023 Functional genomic analysis delineates regulatory mechanisms of GWAS-identified bipolar disorder risk variants, Chang Hong, 2022 A Human-Specific Schizophrenia Risk Tandem Repeat Affects Alternative Splicing of a Human-Unique Isoform AS3MT(d2d3) and Mushroom Dendritic Spine Density, Chang Hong, 2021 Independent replications and integrative analyses confirmTRANK1as a susceptibility gene for bipolar disorder, Chang Hong, 2021 Functional Genomics Identify a Regulatory Risk Variation rs4420550 in the 16p11.2 Schizophrenia-Associated Locus, Chang Hong, 2021 Regulation of TRANK1 by GSK-3 in the brain: unexpected interactions, Chang Hong, 2021 Integrative analyses of major histocompatibility complex loci in the genome-wide association studies of major depressive disorder, Chang Hong, 2019 Interactome Analyses implicated CAMK2A in the genetic predisposition and pharmacological mechanism of Bipolar Disorder, Chang Hong, 2019 The protocadherin 17 gene affects cognition, personality, amygdala structure and function, synapse development and risk of major mood disorders, Chang Hong, 2018 Replicated associations of FADS1, MAD1L1, and a rare variant at 10q26.13 with bipolar disorder in Chinese population, Chang Hong, 2018 Rare and common variants at 16p11.2 are associated with schizophrenia, Chang Hong, 2017 The schizophrenia risk gene ZNF804A: clinical associations, biological mechanisms and neuronal functions, Chang Hong, 2017 Evaluation of European Schizophrenia GWAS Loci in Asian Populations via Comprehensive Meta-Analyses, Chang Hong, 2017 Identification of a Bipolar Disorder Vulnerable Gene CHDH at 3p21.1, Chang Hong, 2017 Replication analyses of four chromosomal deletions with schizophrenia via independent large-scale meta-analyses, Chang Hong, 2016 CRISPR/cas9, a novel genomic tool to knock down microRNA in vitro and in vivo, Chang Hong, 2016 Expression and distribution of symplekin regulates the assembly and function of the epithelial tight junction, Chang Hong, 2012 Methylation of tumor associated genes in tissue and plasma samples from liver disease patients, Chang Hong, 2008

Areas of Focus

Functional Genomics of Psychiatric Disorders

Publications

Reduced Vrk2 expression is associated with higher risk of depression in humans and mediates depressive-like behaviors in mice, Chang Hong, 2023
Identification of a psychiatric risk gene NISCH at 3p21.1 GWAS locus mediating dendritic spine morphogenesis and cognitive function, Chang Hong, 2023
Functional genomic analysis delineates regulatory mechanisms of GWAS-identified bipolar disorder risk variants, Chang Hong, 2022
A Human-Specific Schizophrenia Risk Tandem Repeat Affects Alternative Splicing of a Human-Unique Isoform AS3MT(d2d3) and Mushroom Dendritic Spine Density, Chang Hong, 2021
Independent replications and integrative analyses confirmTRANK1as a susceptibility gene for bipolar disorder, Chang Hong, 2021
Functional Genomics Identify a Regulatory Risk Variation rs4420550 in the 16p11.2 Schizophrenia-Associated Locus, Chang Hong, 2021
Regulation of TRANK1 by GSK-3 in the brain: unexpected interactions, Chang Hong, 2021
Integrative analyses of major histocompatibility complex loci in the genome-wide association studies of major depressive disorder, Chang Hong, 2019
Interactome Analyses implicated CAMK2A in the genetic predisposition and pharmacological mechanism of Bipolar Disorder, Chang Hong, 2019
The protocadherin 17 gene affects cognition, personality, amygdala structure and function, synapse development and risk of major mood disorders, Chang Hong, 2018
Replicated associations of FADS1, MAD1L1, and a rare variant at 10q26.13 with bipolar disorder in Chinese population, Chang Hong, 2018
Rare and common variants at 16p11.2 are associated with schizophrenia, Chang Hong, 2017
The schizophrenia risk gene ZNF804A: clinical associations, biological mechanisms and neuronal functions, Chang Hong, 2017
Evaluation of European Schizophrenia GWAS Loci in Asian Populations via Comprehensive Meta-Analyses, Chang Hong, 2017
Identification of a Bipolar Disorder Vulnerable Gene CHDH at 3p21.1, Chang Hong, 2017
Replication analyses of four chromosomal deletions with schizophrenia via independent large-scale meta-analyses, Chang Hong, 2016
CRISPR/cas9, a novel genomic tool to knock down microRNA in vitro and in vivo, Chang Hong, 2016
Expression and distribution of symplekin regulates the assembly and function of the epithelial tight junction, Chang Hong, 2012
Methylation of tumor associated genes in tissue and plasma samples from liver disease patients, Chang Hong, 2008

Genomics Psychiatric Disorders Depression Schizophrenia Bipolar Disorder Gene Expression Neurodevelopment Risk Variants Molecular Mechanisms Functional Analysis

Chao Chen - Central South University

Jun Yao - Tsinghua University

Jun Yao - Tsinghua University

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