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常宏
Life Science
中国科学院大学
云南
Language: 中文, 英语
基因组学
精神疾病
抑郁症
精神分裂症
双相情感障碍
基因表达
神经发育
风险变异
分子机制
功能分析
Areas of Focus
- 精神疾病的功能基因组学
Work Experience
- 2022-01~2022-06 - 昆明动物研究所 - 研究员
- 2017-01~2021-12 - 昆明动物研究所 - 副研究员
- 2016-07~2017-01 - 昆明动物研究所 - 助理研究员
- 2014-01~2016-06 - 美国南阿拉巴马大学Mitchell肿瘤研究所 - 博士后
- 2012-07~2013-09 - 昆明动物研究所 - 助理研究员
- 2011-07~2012-06 - 昆明动物研究所 - 研究实习员
Academic Background & Achievements
- 2008-09--2011-06 理学博士: 中国科学院大学
- 2005-09--2008-06 理学硕士: 云南大学
- 2001-09--2005-06 理学学士: 云南大学
Publications
- Reduced Vrk2 expression is associated with higher risk of depression in humans and mediates depressive-like behaviors in mice, 常宏, 2023
- Identification of a psychiatric risk gene NISCH at 3p21.1 GWAS locus mediating dendritic spine morphogenesis and cognitive function, 常宏, 2023
- Functional genomic analysis delineates regulatory mechanisms of GWAS-identified bipolar disorder risk variants, 常宏, 2022
- A Human-Specific Schizophrenia Risk Tandem Repeat Affects Alternative Splicing of a Human-Unique Isoform AS3MT(d2d3) and Mushroom Dendritic Spine Density, 常宏, 2021
- Independent replications and integrative analyses confirmTRANK1as a susceptibility gene for bipolar disorder, 常宏, 2021
- Functional Genomics Identify a Regulatory Risk Variation rs4420550 in the 16p11.2 Schizophrenia-Associated Locus, 常宏, 2021
- Regulation of TRANK1 by GSK-3 in the brain: unexpected interactions, 常宏, 2021
- Integrative analyses of major histocompatibility complex loci in the genome-wide association studies of major depressive disorder, 常宏, 2019
- Interactome Analyses implicated CAMK2A in the genetic predisposition and pharmacological mechanism of Bipolar Disorder, 常宏, 2019
- The protocadherin 17 gene affects cognition, personality, amygdala structure and function, synapse development and risk of major mood disorders, 常宏, 2018
- Replicated associations of FADS1, MAD1L1, and a rare variant at 10q26.13 with bipolar disorder in Chinese population, 常宏, 2018
- Rare and common variants at 16p11.2 are associated with schizophrenia, 常宏, 2017
- The schizophrenia risk gene ZNF804A: clinical associations, biological mechanisms and neuronal functions, 常宏, 2017
- Evaluation of European Schizophrenia GWAS Loci in Asian Populations via Comprehensive Meta-Analyses, 常宏, 2017
- Identification of a Bipolar Disorder Vulnerable Gene CHDH at 3p21.1, 常宏, 2017
- Replication analyses of four chromosomal deletions with schizophrenia via independent large-scale meta-analyses, 常宏, 2016
- CRISPR/cas9, a novel genomic tool to knock down microRNA in vitro and in vivo, 常宏, 2016
- Expression and distribution of symplekin regulates the assembly and function of the epithelial tight junction, 常宏, 2012
- Methylation of tumor associated genes in tissue and plasma samples from liver disease patients, 常宏, 2008
