Professor | 常宏 | 数字化转型顾问

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Name	常宏
Contact Information	changhong@mail.kiz.ac.cn
Language ability	中文, 英语
Province	云南

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Name

常宏

Contact Information

changhong@mail.kiz.ac.cn

Language ability

中文, 英语

Province

云南

University/Lab Affiliation and Title	中国科学院大学
Faculty	Life Sciences
Academic Background & Achievements	2008-09--2011-06 理学博士: 中国科学院大学 2005-09--2008-06 理学硕士: 云南大学 2001-09--2005-06 理学学士: 云南大学
Work Experience	2022-01~2022-06 - 昆明动物研究所 - 研究员 2017-01~2021-12 - 昆明动物研究所 - 副研究员 2016-07~2017-01 - 昆明动物研究所 - 助理研究员 2014-01~2016-06 - 美国南阿拉巴马大学Mitchell肿瘤研究所 - 博士后 2012-07~2013-09 - 昆明动物研究所 - 助理研究员 2011-07~2012-06 - 昆明动物研究所 - 研究实习员

University/Lab Affiliation and Title

中国科学院大学

Faculty

Life Sciences

Academic Background & Achievements

2008-09--2011-06 理学博士: 中国科学院大学
2005-09--2008-06 理学硕士: 云南大学
2001-09--2005-06 理学学士: 云南大学

Work Experience

2022-01~2022-06 - 昆明动物研究所 - 研究员
2017-01~2021-12 - 昆明动物研究所 - 副研究员
2016-07~2017-01 - 昆明动物研究所 - 助理研究员
2014-01~2016-06 - 美国南阿拉巴马大学Mitchell肿瘤研究所 - 博士后
2012-07~2013-09 - 昆明动物研究所 - 助理研究员
2011-07~2012-06 - 昆明动物研究所 - 研究实习员

Areas of Focus	精神疾病的功能基因组学
Publications	Reduced Vrk2 expression is associated with higher risk of depression in humans and mediates depressive-like behaviors in mice, 常宏, 2023 Identification of a psychiatric risk gene NISCH at 3p21.1 GWAS locus mediating dendritic spine morphogenesis and cognitive function, 常宏, 2023 Functional genomic analysis delineates regulatory mechanisms of GWAS-identified bipolar disorder risk variants, 常宏, 2022 A Human-Specific Schizophrenia Risk Tandem Repeat Affects Alternative Splicing of a Human-Unique Isoform AS3MT(d2d3) and Mushroom Dendritic Spine Density, 常宏, 2021 Independent replications and integrative analyses confirmTRANK1as a susceptibility gene for bipolar disorder, 常宏, 2021 Functional Genomics Identify a Regulatory Risk Variation rs4420550 in the 16p11.2 Schizophrenia-Associated Locus, 常宏, 2021 Regulation of TRANK1 by GSK-3 in the brain: unexpected interactions, 常宏, 2021 Integrative analyses of major histocompatibility complex loci in the genome-wide association studies of major depressive disorder, 常宏, 2019 Interactome Analyses implicated CAMK2A in the genetic predisposition and pharmacological mechanism of Bipolar Disorder, 常宏, 2019 The protocadherin 17 gene affects cognition, personality, amygdala structure and function, synapse development and risk of major mood disorders, 常宏, 2018 Replicated associations of FADS1, MAD1L1, and a rare variant at 10q26.13 with bipolar disorder in Chinese population, 常宏, 2018 Rare and common variants at 16p11.2 are associated with schizophrenia, 常宏, 2017 The schizophrenia risk gene ZNF804A: clinical associations, biological mechanisms and neuronal functions, 常宏, 2017 Evaluation of European Schizophrenia GWAS Loci in Asian Populations via Comprehensive Meta-Analyses, 常宏, 2017 Identification of a Bipolar Disorder Vulnerable Gene CHDH at 3p21.1, 常宏, 2017 Replication analyses of four chromosomal deletions with schizophrenia via independent large-scale meta-analyses, 常宏, 2016 CRISPR/cas9, a novel genomic tool to knock down microRNA in vitro and in vivo, 常宏, 2016 Expression and distribution of symplekin regulates the assembly and function of the epithelial tight junction, 常宏, 2012 Methylation of tumor associated genes in tissue and plasma samples from liver disease patients, 常宏, 2008

Areas of Focus

精神疾病的功能基因组学

Publications

Reduced Vrk2 expression is associated with higher risk of depression in humans and mediates depressive-like behaviors in mice, 常宏, 2023
Identification of a psychiatric risk gene NISCH at 3p21.1 GWAS locus mediating dendritic spine morphogenesis and cognitive function, 常宏, 2023
Functional genomic analysis delineates regulatory mechanisms of GWAS-identified bipolar disorder risk variants, 常宏, 2022
A Human-Specific Schizophrenia Risk Tandem Repeat Affects Alternative Splicing of a Human-Unique Isoform AS3MT(d2d3) and Mushroom Dendritic Spine Density, 常宏, 2021
Independent replications and integrative analyses confirmTRANK1as a susceptibility gene for bipolar disorder, 常宏, 2021
Functional Genomics Identify a Regulatory Risk Variation rs4420550 in the 16p11.2 Schizophrenia-Associated Locus, 常宏, 2021
Regulation of TRANK1 by GSK-3 in the brain: unexpected interactions, 常宏, 2021
Integrative analyses of major histocompatibility complex loci in the genome-wide association studies of major depressive disorder, 常宏, 2019
Interactome Analyses implicated CAMK2A in the genetic predisposition and pharmacological mechanism of Bipolar Disorder, 常宏, 2019
The protocadherin 17 gene affects cognition, personality, amygdala structure and function, synapse development and risk of major mood disorders, 常宏, 2018
Replicated associations of FADS1, MAD1L1, and a rare variant at 10q26.13 with bipolar disorder in Chinese population, 常宏, 2018
Rare and common variants at 16p11.2 are associated with schizophrenia, 常宏, 2017
The schizophrenia risk gene ZNF804A: clinical associations, biological mechanisms and neuronal functions, 常宏, 2017
Evaluation of European Schizophrenia GWAS Loci in Asian Populations via Comprehensive Meta-Analyses, 常宏, 2017
Identification of a Bipolar Disorder Vulnerable Gene CHDH at 3p21.1, 常宏, 2017
Replication analyses of four chromosomal deletions with schizophrenia via independent large-scale meta-analyses, 常宏, 2016
CRISPR/cas9, a novel genomic tool to knock down microRNA in vitro and in vivo, 常宏, 2016
Expression and distribution of symplekin regulates the assembly and function of the epithelial tight junction, 常宏, 2012
Methylation of tumor associated genes in tissue and plasma samples from liver disease patients, 常宏, 2008

基因组学精神疾病抑郁症精神分裂症双相情感障碍基因表达神经发育风险变异分子机制功能分析

张梦杰 - 同济大学

Area of Focus
基因表达 | 调控 | 组织 | 干细胞 | 发育 | 分化 | 模式生物 | Survivin | 癌症治疗 | 分子机制

余庆波 - 上海师范大学

Area of Focus
叶绿体 | 质体 | 基因表达 | 调控 | 高等植物 | 发育 | 转录 | 翻译 | 拟南芥 | 分子机制

朱骏 - 上海师范大学

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