Professor | Sheng Ye | Asia Growth Partners

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Name	Sheng Ye
Language ability	Chinese, English
Province	Zhejiang

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Name

Sheng Ye

Language ability

Chinese, English

Province

Zhejiang

University/Lab Affiliation and Title	Zhejiang University
Faculty	Life Sciences
Academic Background & Achievements	1987-1991 Bachelor in Cell Biology: Xiamen University 1991-1996 PhD in Biophysics: Institute of Biophysics, Chinese Academy of Sciences 1996-1999 Postdoctoral Fellow in Biochemistry: Baylor College of Medicine 1999-2001 Postdoctoral Fellow in Biochemistry: University of Texas Southwestern Medical Center
Work Experience	2001-2003 Scientist at Syrrx, USA 2003-2005 Scientist at Texas A&M Health Science Center, USA 2005-2010 Lecturer, Research Specialist Level II, Assistant Professor at University of Texas Southwestern Medical Center/Howard Hughes Medical Institute, USA 2010-2014 Professor, Researcher at Zhejiang University, Life Sciences Institute 2015-present Professor, Senior Researcher at Zhejiang University, Life Sciences Institute
Awards	2010 Zhejiang Province Outstanding Youth Fund recipient 2010 Ministry of Education New Century Excellent Talents Support Plan 2015 National Outstanding Youth Fund recipient 2016 Qiushi Distinguished Professor at Zhejiang University

University/Lab Affiliation and Title

Zhejiang University

Faculty

Life Sciences

Academic Background & Achievements

1987-1991 Bachelor in Cell Biology: Xiamen University
1991-1996 PhD in Biophysics: Institute of Biophysics, Chinese Academy of Sciences
1996-1999 Postdoctoral Fellow in Biochemistry: Baylor College of Medicine
1999-2001 Postdoctoral Fellow in Biochemistry: University of Texas Southwestern Medical Center

Work Experience

2001-2003 Scientist at Syrrx, USA
2003-2005 Scientist at Texas A&M Health Science Center, USA
2005-2010 Lecturer, Research Specialist Level II, Assistant Professor at University of Texas Southwestern Medical Center/Howard Hughes Medical Institute, USA
2010-2014 Professor, Researcher at Zhejiang University, Life Sciences Institute
2015-present Professor, Senior Researcher at Zhejiang University, Life Sciences Institute

Awards

2010 Zhejiang Province Outstanding Youth Fund recipient
2010 Ministry of Education New Century Excellent Talents Support Plan
2015 National Outstanding Youth Fund recipient
2016 Qiushi Distinguished Professor at Zhejiang University

Areas of Focus	Molecular mechanisms of Z-ring contraction in bacterial cell division Molecular mechanisms of anomalous mole-fraction effect in potassium ion channels
Publications	A Rational Approach to Enhancing Antibody Fc Homodimer Formation for Robust Production of Antibody Mixture in a Single Cell Line, Jie Yu, Xiaoxiao Wang, Tao Xu, Qiuheng Jin, Jinyuan Duan, Jie Wu, Haiyan Wu, Ting Xu, Sheng Ye, 2017 Ionic interactions of Ba2+ blockades in the MthK K+ channel, Guo R, Zeng W, Cui HJ, Chen L, Ye S, 2014 FtsZ Protofilaments use a hinge-opening mechanism for constrictive force generation, Li Y, Hsin J, Zhao L, Cheng Y, Shang W, Huang KC, Wang HW, Ye S, 2013 Structural Basis of Heparan Sulfate-Specific Degradation by Heparinase III, Dong W, Lu W, McKeehan WL, Luo Y, Ye S, 2012 Novel insights into ion selectivity from high resolution structures of an open K+ channel pore, Ye S, Li Y, Chen L, Jiang Y, 2010 Crystal structures of a Ligand-free MthK gating ring: Insights into the ligand gating mechanism of K+ channel, Ye S, Li Y, Chen L, Jiang Y, 2006

Areas of Focus

Molecular mechanisms of Z-ring contraction in bacterial cell division
Molecular mechanisms of anomalous mole-fraction effect in potassium ion channels

Publications

A Rational Approach to Enhancing Antibody Fc Homodimer Formation for Robust Production of Antibody Mixture in a Single Cell Line, Jie Yu, Xiaoxiao Wang, Tao Xu, Qiuheng Jin, Jinyuan Duan, Jie Wu, Haiyan Wu, Ting Xu, Sheng Ye, 2017
Ionic interactions of Ba2+ blockades in the MthK K+ channel, Guo R, Zeng W, Cui HJ, Chen L, Ye S, 2014
FtsZ Protofilaments use a hinge-opening mechanism for constrictive force generation, Li Y, Hsin J, Zhao L, Cheng Y, Shang W, Huang KC, Wang HW, Ye S, 2013
Structural Basis of Heparan Sulfate-Specific Degradation by Heparinase III, Dong W, Lu W, McKeehan WL, Luo Y, Ye S, 2012
Novel insights into ion selectivity from high resolution structures of an open K+ channel pore, Ye S, Li Y, Chen L, Jiang Y, 2010
Crystal structures of a Ligand-free MthK gating ring: Insights into the ligand gating mechanism of K+ channel, Ye S, Li Y, Chen L, Jiang Y, 2006

Ftsz Gtp Hydrolysis Constrictive Force Cell Division Molecular Dynamics Protein Structure Bacterial Cytokinesis Mechanical Force Membrane Interaction Protein Interaction Ion Selectivity Potassium Channels Sodium Ions Channel Gating Molecular Structure Biophysics Electrophysiology Ion Transport Protein Engineering Channel Dynamics

Xin Gong - Southern University of Science and Technology

Xiaotian Liu - Southern University of Science and Technology

Qing-Tao Shen - Southern University of Science and Technology

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