Areas of Focus
- Three-dimensional structure analysis of protein machines and their biological functions
- Molecular mechanisms of biomolecular self-assembly
- Decoding and programming of protein condensates
Work Experience
- 2020-present - Life Sciences College, Zhang Mingjie Academician Group - Associate Research Professor
Academic Background & Achievements
- 2003-2008 Bachelor in Biotechnology: University of Science and Technology of China
- 2013-2015 Master in Biochemistry: Hong Kong University of Science and Technology
- 2015-2019 PhD in Biomedical Engineering: Hong Kong University of Science and Technology
Publications
- Structural and mechanistic insights into fungal β-1,3-glucan synthase FKS1, Xiaotian Liu et al., 2023
- Field-dependent deep learning enables high-throughput whole-cell 3D super-resolution imaging, Xiaotian Liu et al., 2023
- Structures and mechanism of chitin synthase and its inhibition by antifungal drug Nikkomycin Z, Xiaotian Liu et al., 2022
- Injectable, photoresponsive hydrogels for axon regeneration enabled by metal-directed protein assembly, Xiaotian Liu et al., 2020
- Cobalt-Cross-Linked, Redox-Responsive Spy Network Protein Hydrogels, Xiaotian Liu et al., 2019
- Versatile engineered protein hydrogels enabling decoupled mechanical and biochemical tuning for cell adhesion and neurite growth, Xiaotian Liu et al., 2018
- Modular functionalization of crystalline graphene by recombinant proteins: a nanoplatform for probing biomolecules, Xiaotian Liu et al., 2018
- Synthesis of Entirely Protein-Based Hydrogels by Enzymatic Oxidation Enabling Water-Resistant Bioadhesion and Stem Cell Encapsulation, Xiaotian Liu et al., 2018
- Alternative splicing creates two new architectures for human tyrosyl-tRNA synthetase, Xiaotian Liu et al., 2016
- Structural basis of cargo recognitions for class V myosins, Xiaotian Liu et al., 2013
- Structural basis for phosphorylated autoinducer-2 modulation of the oligomerization state of the global transcription regulator LsrR from Escherichia coli, Xiaotian Liu et al., 2013
- Cloning, purification, crystallization and preliminary crystallographic analysis of LsrR from Escherichia coli, Xiaotian Liu et al., 2010
Awards
- Hong Kong Technology Talent Scheme Postdoctoral Hub for ITF (2020)
- Chan Tak Kei & Wong Kwai Ying Bioengineering Student Research Award (2019)
- HKJEBN Scholarship for Talents (2016-2019)