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Li Shen
Life Science
Zhejiang University
Zhejiang
Language: Chinese, English
Dna Methylation
Demethylation
Histone Modification
Non-Coding Rna
Epigenetics
Pluripotency
Stem Cells
Tumor Development
Immune Diseases
High-Throughput Sequencing
Areas of Focus
- Dynamic regulation of DNA methylation and demethylation and its interaction with other epigenetic regulatory mechanisms such as histone modification and non-coding RNA
- Epigenetic regulation mechanisms in development and cellular pluripotency, and their roles in induced pluripotent stem cells and cell transdifferentiation
- Epigenetic regulatory networks in the occurrence and development of tumors and immune system diseases, and new drug research targeting epigenetic regulatory proteins
- New applications of high-throughput sequencing technology and microfluidic chips in epigenetic research, and the development of related data analysis software
Work Experience
- 2011-2012 Postdoctoral Fellow, Lineberger Comprehensive Cancer Center, University of North Carolina, USA
- 2012-2015 Postdoctoral Fellow, Department of Genetics, Harvard Medical School/HHMI/Boston Children's Hospital, USA
- 2015-present Professor, Researcher, Zhejiang University, School of Life Sciences
Academic Background & Achievements
- 2000-2004 Bachelor: Nanjing University, Kuang Yaming Honors School
- 2004-2010 PhD: Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences
- Recipient of the National Science Fund for Distinguished Young Scholars
- Recipient of the Zhejiang Outstanding Youth Fund
