Professor | Liheng Wang | Asia Growth Partners

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Name	Liheng Wang
Contact Information	lihengwang@bjmu.edu.cn
Language ability	English, Chinese
Province	Beijing

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Name

Liheng Wang

Contact Information

lihengwang@bjmu.edu.cn

Language ability

English, Chinese

Province

Beijing

University/Lab Affiliation and Title	Peking University
Faculty	Basic Medical Sciences
Academic Background & Achievements	2003-2007 Bachelor in Biological Sciences, China Agricultural University 2007-2009 Master in Physiology and Biophysics, University of Arkansas 2009-2015 PhD in Nutrition and Metabolic Biology, Columbia University
Work Experience	2015-2016 Postdoctoral Fellow in Pediatrics, Columbia University 2016-2018 Postdoctoral Fellow in Endocrinology, Columbia University 2018-2022 Assistant Research Scientist in Endocrinology, Columbia University 2022-2023 Assistant Professor at the Metabolic Research Institute, Mount Sinai School of Medicine
Awards	2019 Regeneron scholarship for the 2019 Cold Spring Harbor Laboratory course 'Computational Genomics' 2014 Keystone Symposia scholarship 'A Multisystems Perspective' 2012 Travel award of the 2nd International Hyperphagia Conference 2012 Travel award of the NIDDK 'Body Fat Disorders' Conference 2011 Marija Chouinard Awards for Excellence in Research, Institute of Human Nutrition, Columbia University (Highest award for IHN student)

University/Lab Affiliation and Title

Peking University

Faculty

Basic Medical Sciences

Academic Background & Achievements

2003-2007 Bachelor in Biological Sciences, China Agricultural University
2007-2009 Master in Physiology and Biophysics, University of Arkansas
2009-2015 PhD in Nutrition and Metabolic Biology, Columbia University

Work Experience

2015-2016 Postdoctoral Fellow in Pediatrics, Columbia University
2016-2018 Postdoctoral Fellow in Endocrinology, Columbia University
2018-2022 Assistant Research Scientist in Endocrinology, Columbia University
2022-2023 Assistant Professor at the Metabolic Research Institute, Mount Sinai School of Medicine

Awards

2019 Regeneron scholarship for the 2019 Cold Spring Harbor Laboratory course 'Computational Genomics'
2014 Keystone Symposia scholarship 'A Multisystems Perspective'
2012 Travel award of the 2nd International Hyperphagia Conference
2012 Travel award of the NIDDK 'Body Fat Disorders' Conference
2011 Marija Chouinard Awards for Excellence in Research, Institute of Human Nutrition, Columbia University (Highest award for IHN student)

Areas of Focus	Transcriptional regulation of hepatic glucose and lipid metabolism
Publications	TOX4, an insulin receptor-independent regulator of hepatic glucose production, is activated in diabetic liver, Wang L, Yu J, Zhou Q, Wang X, Mukhanova M, Du W, Sun L, Pajvani UB, Accili D, 2022 Adipsin promotes bone marrow adiposity by priming mesenchymal stem cells, Aaron N, Kraakman MJ, Zhou Q, Liu Q, Costa S, Yang J, Liu L, Yu L, Wang L, He Y, Fan L, Hirakawa H, Ding L, Lo J, Wang W, Zhao B, Guo E, Sun L, Rosen CJ, Qiang L, 2021 Bardet-Biedl syndrome proteins regulate intracellular signaling and neuronal function in patient-specific iPSC-derived neurons, Wang L, Liu Y, Stratigopoulos G, Panigrahi SK, Sui L, Zhang Y, LeDuc CA, Glover HJ, De Rosa MC, Burnett LC, Williams DJ, Shang L, Goland R, Tsang SH, Wardlaw SL, Egli D, Zheng D, Doege CA, Leibel RL, 2021 Inhibition of PU.1 ameliorates metabolic dysfunction and non-alcoholic steatohepatitis, Liu Q, Yu J, Wang L, Tang Y, Zhou Q, Ji S, Wang Y, Santos L, Haeusler RA, Que J, Rajbhandari P, Lei X, Valenti L, Pajvani UB, Qin J, Qiang L, 2020 Identification of insulin-responsive transcription factors that regulate glucose production by hepatocytes, Wang L, Liu Q, Kitamoto T, Hou J, Qin J, Accili D, 2019 Ciliary gene RPGRIP1L is required for hypothalamic arcuate neuron development, Wang L, De Solis AJ, Goffer Y, Kathryn E. Birkenbach KE, Engle SE, Tanis R, Levenson JM, Li X, Rausch R, Purohit M, Lee J, Tan J, De Rosa MC, Doege CA, Aaron HL, Martins GJ, Brüning JC, Egli D, Costa R, Berbari N, Leibel RL, Stratigopoulos G, 2019 PC1/3 Deficiency Impacts Pro-opiomelanocortin Processing in Human Embryonic Stem Cell-Derived Hypothalamic Neurons, Wang L, Sui L, Panigrahi SK, Meece K, Doege CA, Wardlaw SL, Egli D, Leibel RL, 2017 Deficiency in prohormone convertase PC1 impairs prohormone processing in Prader-Willi syndrome, Burnett LC, LeDuc CA, Sulsona CR, Paull D, Rausch R, Eddiry S, Carli JF, Morabito MV, Skowronski AA, Hubner G, Zimmer M, Wang L, Day R, Levy B, Fennoy I, Dubern B, Poitou C, Clement K, Butler MG, Rosenbaum M, Salles JP, Tauber M, Driscoll DJ, Egli D, Leibel RL, 2017 Efficient generation of hypothalamic neurons from human pluripotent stem cells, Wang L, Egli D, Leibel RL, 2016 Differentiation of hypothalamic-like neurons from human pluripotent stem cells, Wang L, Meece K, Williams DJ, Lo KA, Zimmer M, Heinrich G, Martin Carli J, Leduc CA, Sun L, Zeltser LM, Freeby M, Goland R, Tsang SH, Wardlaw SL, Egli D, Leibel RL, 2015

Areas of Focus

Transcriptional regulation of hepatic glucose and lipid metabolism

Publications

TOX4, an insulin receptor-independent regulator of hepatic glucose production, is activated in diabetic liver, Wang L, Yu J, Zhou Q, Wang X, Mukhanova M, Du W, Sun L, Pajvani UB, Accili D, 2022
Adipsin promotes bone marrow adiposity by priming mesenchymal stem cells, Aaron N, Kraakman MJ, Zhou Q, Liu Q, Costa S, Yang J, Liu L, Yu L, Wang L, He Y, Fan L, Hirakawa H, Ding L, Lo J, Wang W, Zhao B, Guo E, Sun L, Rosen CJ, Qiang L, 2021
Bardet-Biedl syndrome proteins regulate intracellular signaling and neuronal function in patient-specific iPSC-derived neurons, Wang L, Liu Y, Stratigopoulos G, Panigrahi SK, Sui L, Zhang Y, LeDuc CA, Glover HJ, De Rosa MC, Burnett LC, Williams DJ, Shang L, Goland R, Tsang SH, Wardlaw SL, Egli D, Zheng D, Doege CA, Leibel RL, 2021
Inhibition of PU.1 ameliorates metabolic dysfunction and non-alcoholic steatohepatitis, Liu Q, Yu J, Wang L, Tang Y, Zhou Q, Ji S, Wang Y, Santos L, Haeusler RA, Que J, Rajbhandari P, Lei X, Valenti L, Pajvani UB, Qin J, Qiang L, 2020
Identification of insulin-responsive transcription factors that regulate glucose production by hepatocytes, Wang L, Liu Q, Kitamoto T, Hou J, Qin J, Accili D, 2019
Ciliary gene RPGRIP1L is required for hypothalamic arcuate neuron development, Wang L, De Solis AJ, Goffer Y, Kathryn E. Birkenbach KE, Engle SE, Tanis R, Levenson JM, Li X, Rausch R, Purohit M, Lee J, Tan J, De Rosa MC, Doege CA, Aaron HL, Martins GJ, Brüning JC, Egli D, Costa R, Berbari N, Leibel RL, Stratigopoulos G, 2019
PC1/3 Deficiency Impacts Pro-opiomelanocortin Processing in Human Embryonic Stem Cell-Derived Hypothalamic Neurons, Wang L, Sui L, Panigrahi SK, Meece K, Doege CA, Wardlaw SL, Egli D, Leibel RL, 2017
Deficiency in prohormone convertase PC1 impairs prohormone processing in Prader-Willi syndrome, Burnett LC, LeDuc CA, Sulsona CR, Paull D, Rausch R, Eddiry S, Carli JF, Morabito MV, Skowronski AA, Hubner G, Zimmer M, Wang L, Day R, Levy B, Fennoy I, Dubern B, Poitou C, Clement K, Butler MG, Rosenbaum M, Salles JP, Tauber M, Driscoll DJ, Egli D, Leibel RL, 2017
Efficient generation of hypothalamic neurons from human pluripotent stem cells, Wang L, Egli D, Leibel RL, 2016
Differentiation of hypothalamic-like neurons from human pluripotent stem cells, Wang L, Meece K, Williams DJ, Lo KA, Zimmer M, Heinrich G, Martin Carli J, Leduc CA, Sun L, Zeltser LM, Freeby M, Goland R, Tsang SH, Wardlaw SL, Egli D, Leibel RL, 2015

Transcriptional Regulation Hepatic Glucose Metabolism Lipid Metabolism Metabolic Biology Endocrinology Gene Expression Liver Function Metabolic Disorders Diabetes Research

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