Professor | 汪丽恒 | 数字化转型顾问

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Name	汪丽恒
Contact Information	lihengwang@bjmu.edu.cn
Language ability	英语, 汉语
Province	北京

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Name

汪丽恒

Contact Information

lihengwang@bjmu.edu.cn

Language ability

英语, 汉语

Province

北京

University/Lab Affiliation and Title	北京大学
Faculty	Basic Medical Sciences
Academic Background & Achievements	2003-2007 中国农业大学生物科学本科 2007-2009 美国阿肯色大学生理与生物物理硕士 2009-2015 美国哥伦比亚大学营养与代谢生物学博士
Work Experience	2015-2016 哥伦比亚大学儿科博士后 2016-2018 哥伦比亚大学内分泌专业博士后 2018-2022 哥伦比亚大学内分泌助理研究员 2022-2023 美国纽约西奈山医学院代谢研究所助理教授
Awards	2019 Regeneron奖学金，2019年Cold Spring Harbor实验室课程'计算基因组学' 2014 Keystone Symposia奖学金'多系统观点' 2012 第二届国际暴食症会议旅行奖 2012 NIDDK'体脂肪疾病'会议旅行奖 2011 Marija Chouinard研究卓越奖，哥伦比亚大学人类营养研究所（IHN学生最高奖）

University/Lab Affiliation and Title

北京大学

Faculty

Basic Medical Sciences

Academic Background & Achievements

2003-2007 中国农业大学生物科学本科
2007-2009 美国阿肯色大学生理与生物物理硕士
2009-2015 美国哥伦比亚大学营养与代谢生物学博士

Work Experience

2015-2016 哥伦比亚大学儿科博士后
2016-2018 哥伦比亚大学内分泌专业博士后
2018-2022 哥伦比亚大学内分泌助理研究员
2022-2023 美国纽约西奈山医学院代谢研究所助理教授

Awards

2019 Regeneron奖学金，2019年Cold Spring Harbor实验室课程'计算基因组学'
2014 Keystone Symposia奖学金'多系统观点'
2012 第二届国际暴食症会议旅行奖
2012 NIDDK'体脂肪疾病'会议旅行奖
2011 Marija Chouinard研究卓越奖，哥伦比亚大学人类营养研究所（IHN学生最高奖）

Areas of Focus	肝脏糖脂代谢的转录调控
Publications	TOX4, an insulin receptor-independent regulator of hepatic glucose production, is activated in diabetic liver, Wang L, Yu J, Zhou Q, Wang X, Mukhanova M, Du W, Sun L, Pajvani UB, Accili D, 2022 Adipsin promotes bone marrow adiposity by priming mesenchymal stem cells, Aaron N, Kraakman MJ, Zhou Q, Liu Q, Costa S, Yang J, Liu L, Yu L, Wang L, He Y, Fan L, Hirakawa H, Ding L, Lo J, Wang W, Zhao B, Guo E, Sun L, Rosen CJ, Qiang L, 2021 Bardet-Biedl syndrome proteins regulate intracellular signaling and neuronal function in patient-specific iPSC-derived neurons, Wang L, Liu Y, Stratigopoulos G, Panigrahi SK, Sui L, Zhang Y, LeDuc CA, Glover HJ, De Rosa MC, Burnett LC, Williams DJ, Shang L, Goland R, Tsang SH, Wardlaw SL, Egli D, Zheng D, Doege CA, Leibel RL, 2021 Inhibition of PU.1 ameliorates metabolic dysfunction and non-alcoholic steatohepatitis, Liu Q, Yu J, Wang L, Tang Y, Zhou Q, Ji S, Wang Y, Santos L, Haeusler RA, Que J, Rajbhandari P, Lei X, Valenti L, Pajvani UB, Qin J, Qiang L, 2020 Identification of insulin-responsive transcription factors that regulate glucose production by hepatocytes, Wang L, Liu Q, Kitamoto T, Hou J, Qin J, Accili D, 2019 Ciliary gene RPGRIP1L is required for hypothalamic arcuate neuron development, Wang L, De Solis AJ, Goffer Y, Kathryn E. Birkenbach KE, Engle SE, Tanis R, Levenson JM, Li X, Rausch R, Purohit M, Lee J, Tan J, De Rosa MC, Doege CA, Aaron HL, Martins GJ, Brüning JC, Egli D, Costa R, Berbari N, Leibel RL, Stratigopoulos G, 2019 PC1/3 Deficiency Impacts Pro-opiomelanocortin Processing in Human Embryonic Stem Cell-Derived Hypothalamic Neurons, Wang L, Sui L, Panigrahi SK, Meece K, Doege CA, Wardlaw SL, Egli D, Leibel RL, 2017 Deficiency in prohormone convertase PC1 impairs prohormone processing in Prader-Willi syndrome, Burnett LC, LeDuc CA, Sulsona CR, Paull D, Rausch R, Eddiry S, Carli JF, Morabito MV, Skowronski AA, Hubner G, Zimmer M, Wang L, Day R, Levy B, Fennoy I, Dubern B, Poitou C, Clement K, Butler MG, Rosenbaum M, Salles JP, Tauber M, Driscoll DJ, Egli D, Leibel RL, 2017 Efficient generation of hypothalamic neurons from human pluripotent stem cells, Wang L, Egli D, Leibel RL, 2016 Differentiation of hypothalamic-like neurons from human pluripotent stem cells, Wang L, Meece K, Williams DJ, Lo KA, Zimmer M, Heinrich G, Martin Carli J, Leduc CA, Sun L, Zeltser LM, Freeby M, Goland R, Tsang SH, Wardlaw SL, Egli D, Leibel RL, 2015

Areas of Focus

肝脏糖脂代谢的转录调控

Publications

TOX4, an insulin receptor-independent regulator of hepatic glucose production, is activated in diabetic liver, Wang L, Yu J, Zhou Q, Wang X, Mukhanova M, Du W, Sun L, Pajvani UB, Accili D, 2022
Adipsin promotes bone marrow adiposity by priming mesenchymal stem cells, Aaron N, Kraakman MJ, Zhou Q, Liu Q, Costa S, Yang J, Liu L, Yu L, Wang L, He Y, Fan L, Hirakawa H, Ding L, Lo J, Wang W, Zhao B, Guo E, Sun L, Rosen CJ, Qiang L, 2021
Bardet-Biedl syndrome proteins regulate intracellular signaling and neuronal function in patient-specific iPSC-derived neurons, Wang L, Liu Y, Stratigopoulos G, Panigrahi SK, Sui L, Zhang Y, LeDuc CA, Glover HJ, De Rosa MC, Burnett LC, Williams DJ, Shang L, Goland R, Tsang SH, Wardlaw SL, Egli D, Zheng D, Doege CA, Leibel RL, 2021
Inhibition of PU.1 ameliorates metabolic dysfunction and non-alcoholic steatohepatitis, Liu Q, Yu J, Wang L, Tang Y, Zhou Q, Ji S, Wang Y, Santos L, Haeusler RA, Que J, Rajbhandari P, Lei X, Valenti L, Pajvani UB, Qin J, Qiang L, 2020
Identification of insulin-responsive transcription factors that regulate glucose production by hepatocytes, Wang L, Liu Q, Kitamoto T, Hou J, Qin J, Accili D, 2019
Ciliary gene RPGRIP1L is required for hypothalamic arcuate neuron development, Wang L, De Solis AJ, Goffer Y, Kathryn E. Birkenbach KE, Engle SE, Tanis R, Levenson JM, Li X, Rausch R, Purohit M, Lee J, Tan J, De Rosa MC, Doege CA, Aaron HL, Martins GJ, Brüning JC, Egli D, Costa R, Berbari N, Leibel RL, Stratigopoulos G, 2019
PC1/3 Deficiency Impacts Pro-opiomelanocortin Processing in Human Embryonic Stem Cell-Derived Hypothalamic Neurons, Wang L, Sui L, Panigrahi SK, Meece K, Doege CA, Wardlaw SL, Egli D, Leibel RL, 2017
Deficiency in prohormone convertase PC1 impairs prohormone processing in Prader-Willi syndrome, Burnett LC, LeDuc CA, Sulsona CR, Paull D, Rausch R, Eddiry S, Carli JF, Morabito MV, Skowronski AA, Hubner G, Zimmer M, Wang L, Day R, Levy B, Fennoy I, Dubern B, Poitou C, Clement K, Butler MG, Rosenbaum M, Salles JP, Tauber M, Driscoll DJ, Egli D, Leibel RL, 2017
Efficient generation of hypothalamic neurons from human pluripotent stem cells, Wang L, Egli D, Leibel RL, 2016
Differentiation of hypothalamic-like neurons from human pluripotent stem cells, Wang L, Meece K, Williams DJ, Lo KA, Zimmer M, Heinrich G, Martin Carli J, Leduc CA, Sun L, Zeltser LM, Freeby M, Goland R, Tsang SH, Wardlaw SL, Egli D, Leibel RL, 2015

转录调控肝脏糖代谢脂代谢代谢生物学内分泌学基因表达肝功能代谢疾病糖尿病研究

杨春涛 - 广州医科大学

师宪平 - 广州医科大学

于洋 - 北京协和医学院

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