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Xiaofan Wei
Basic Medical Sciences
Peking University
Beijing
Language: Chinese, English
Tumor
Invasion
Metastasis
Molecular Biology
Cell Microenvironment
Integrins
Signaling
Protein Modification
Ubiquitination
Deubiquitination
Areas of Focus
- Molecular biology mechanisms of tumor invasion and metastasis
- Post-translational modifications of proteins in tumor development
Work Experience
- 2011-2012 - Southern Hospital - Work
- 2012-2015 - Peking University, Basic Medical School - Postdoctoral Research
- 2015-present - Peking University, Basic Medical School - Associate Professor
Academic Background & Achievements
- 2011 - PhD: Southern Medical University
- Published 18 research papers
- First/Corresponding author in top journals
Publications
- Single cell profiling of primary and paired metastatic lymph node tumors in breast cancer patients, Liu Tong, Liu Cheng, Yan Meisi, Zhang Lei, Zhang Jing, Xiao Min, Li Zhigao, Wei Xiaofan*, Zhang Hongquan*, 2022
- CBP-mediated Slug acetylation stabilizes Slug and promotes EMT and migration of breast cancer cells, Dai Xiaoyan, Xin Yanli, Xu Weizhi, Tian Xinxia*, Wei Xiaofan*, Zhang Hongquan*, 2021
- Four and a half LIM domains protein 1 can be as a double-edged sword in cancer progression, Wei Xiaofan, Zhang Hongquan, 2020
- Src-mediated phosphorylation converts FHL1 from tumor suppressor to tumor promoter, Wang Xiang, Wei Xiaofan, Yuan Yang, Sun Qingrui, Zhan Jun, Zhang Jing, Tang Yan, Li Feng, Ding Lihua, Ye Qinong, Zhang Hongquan, 2018
- E3 ubiquitin liagse Smurf1 regulates integrin activation by modulating Kindlin-2 ubiquitination and degradation, Wei Xiaofan, Wang Xiang, Zhan Jun, Chen Yuan, Fang Weigang, Fang Lingqiang, Zhang Hongquan, 2017
- Unconventional myosin VIIA promotes melanoma progression, Liu Yuqing, Wei Xiaofan, Guan Lizhao, Xu Sidi, Yuan Yang, Lv Danyu, He Xiaokun, Zhan Jun, Kong Yan, Guo Jun, Zhang Hongquan, 2018
- Roles and Mechanisms of Deubiquitinases (DUBs) in Breast Cancer Progression and Targeted Drug Discovery, Li Sixuan, Zhang Hongquan, Wei Xiaofan*, 2021
- Kindlin-2 mediates activation of TGF-β/Smad signaling and renal fibrosis, Xiaofan Wei, Yang Xia, Feng Li, Yan Tang, Jing Nie, Youhua Liu, Zhanmei Zhou, Hongquan Zhang, Fan Fan Hou, 2013
Awards
- Guangdong Province Science and Technology Progress First Prize
- Peking University Huang Tingfang/Xinhe Young Outstanding Scholar Award
