Professor | Baoxue Yang | Asia Growth Partners

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Name	Baoxue Yang
Language ability	Chinese, English
Province	Beijing

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Name

Baoxue Yang

Language ability

Chinese, English

Province

Beijing

University/Lab Affiliation and Title	Peking University
Faculty	Basic Medical Sciences
Academic Background & Achievements	1984 - Bachelor of Medicine: Norman Bethune College of Medicine 1987 - Master of Medical Genetics: Norman Bethune College of Medicine 1993 - PhD in Immunology: Norman Bethune College of Medicine Published 117 SCI papers, entered Elsevier's list of most influential Chinese scholars for 2014, 2015, and 2016 Filed 11 patents
Work Experience	1994-1997 - Postdoctoral Training at UCSF Cardiovascular Research Institute 1997-2003 - Assistant Researcher at UCSF Cardiovascular Research Institute 2003-2007 - Assistant Professor at UCSF Medical Department 2007-present - Professor at Peking University, School of Basic Medical Sciences, Department of Pharmacology
Awards	Funded by American NIH, PKD, AHA funds, China's 985 Project Fund, 'Major New Drug Creation' National Science and Technology Major Project Fund, National Natural Science Foundation of China, Doctoral Fund of Ministry of Education, International Science and Technology Cooperation Projects of Ministry of Science and Technology, Program for Innovative Research Team in University of Ministry of Education

University/Lab Affiliation and Title

Peking University

Faculty

Basic Medical Sciences

Academic Background & Achievements

1984 - Bachelor of Medicine: Norman Bethune College of Medicine
1987 - Master of Medical Genetics: Norman Bethune College of Medicine
1993 - PhD in Immunology: Norman Bethune College of Medicine
Published 117 SCI papers, entered Elsevier's list of most influential Chinese scholars for 2014, 2015, and 2016
Filed 11 patents

Work Experience

1994-1997 - Postdoctoral Training at UCSF Cardiovascular Research Institute
1997-2003 - Assistant Researcher at UCSF Cardiovascular Research Institute
2003-2007 - Assistant Professor at UCSF Medical Department
2007-present - Professor at Peking University, School of Basic Medical Sciences, Department of Pharmacology

Awards

Funded by American NIH, PKD, AHA funds, China's 985 Project Fund, 'Major New Drug Creation' National Science and Technology Major Project Fund, National Natural Science Foundation of China, Doctoral Fund of Ministry of Education, International Science and Technology Cooperation Projects of Ministry of Science and Technology, Program for Innovative Research Team in University of Ministry of Education

Areas of Focus	Cardiovascular Pharmacology Renal Physiology
Publications	Aquaporin-3 deletion in mice results in renal collecting duct abnormalities and worsens ischemia-reperfusion injury, Lei L., W. Wang, Y. Jia, L. Su, H. Zhou, A. S. Verkman, and B. Yang, 2017 Generation and phenotypic analysis of mice lacking all urea transporters, Jiang T., Y. Li, A. T. Layton, W. Wang, Y. Sun, M. Li, H. Zhou, and B. Yang, 2017 Low molecular weight fucoidan protects renal tubular cells from injury induced by albumin overload, Jia Y., Y. Sun, L. Weng, Y. Li, Q. Zhang, H. Zhou, and B. Yang, 2016 Functional inhibition of urea transporter UT-B enhances endothelial-dependent vasodilation and lowers blood pressure via L-arginine-endothelial nitric oxide synthase-nitric oxide pathway, Sun Y., C. Lau, Y. Jia, Y. Li, W. Wang, J. Ran, F. Li, Y. Huang, H. Zhou, and B. Yang, 2016 Aquaporin-1 retards renal cyst development in polycystic kidney disease by inhibition of Wnt signaling, Wang W., F. Li, Y. Sun, L. Lei, H. Zhou, T. Lei, Y. Xia, A. S. Verkman, and B. Yang, 2015 Ganoderma lucidum polysaccharide peptide prevents renal ischemia reperfusion injury via counteracting oxidative stress, Zhong D., H. Wang, M. Liu, X. Li, M. Huang, H. Zhou, S. Lin, Z. Lin, and B. Yang, 2015 Activation of protein kinase C-α and Src increases urea transporter A1 α-2,6 sialylation, Li X., B. Yang, M. Chen, J. Klein, Jeff. Sands, and G. Chen, 2015 Developing hypothetical inhibition mechanism of novel urea transporter B inhibitor, Li M., W.I. Tou, H. Zhou, F. Li, H. Ren, C.Y. Chen, and B. Yang, 2014 mPGES-2 deletion remarkably enhances liver injury in streptozotocin-treated mouse via induction of GLUT2, Sun Y., Z. Jia, G. Yang, Y. Kakizo, M. Liu, K.Yang, Y. Liu, B. Yang and T. Yang, 2014 A novel small-molecule thienoquinolin urea transporter inhibitor acts as a potential diuretic, Li F., T. Lei, J. Zhu, W. Wang, Y. Sun, J. Chen, Z. Dong, H. Zhou and B. Yang, 2013

Areas of Focus

Cardiovascular Pharmacology
Renal Physiology

Publications

Aquaporin-3 deletion in mice results in renal collecting duct abnormalities and worsens ischemia-reperfusion injury, Lei L., W. Wang, Y. Jia, L. Su, H. Zhou, A. S. Verkman, and B. Yang, 2017
Generation and phenotypic analysis of mice lacking all urea transporters, Jiang T., Y. Li, A. T. Layton, W. Wang, Y. Sun, M. Li, H. Zhou, and B. Yang, 2017
Low molecular weight fucoidan protects renal tubular cells from injury induced by albumin overload, Jia Y., Y. Sun, L. Weng, Y. Li, Q. Zhang, H. Zhou, and B. Yang, 2016
Functional inhibition of urea transporter UT-B enhances endothelial-dependent vasodilation and lowers blood pressure via L-arginine-endothelial nitric oxide synthase-nitric oxide pathway, Sun Y., C. Lau, Y. Jia, Y. Li, W. Wang, J. Ran, F. Li, Y. Huang, H. Zhou, and B. Yang, 2016
Aquaporin-1 retards renal cyst development in polycystic kidney disease by inhibition of Wnt signaling, Wang W., F. Li, Y. Sun, L. Lei, H. Zhou, T. Lei, Y. Xia, A. S. Verkman, and B. Yang, 2015
Ganoderma lucidum polysaccharide peptide prevents renal ischemia reperfusion injury via counteracting oxidative stress, Zhong D., H. Wang, M. Liu, X. Li, M. Huang, H. Zhou, S. Lin, Z. Lin, and B. Yang, 2015
Activation of protein kinase C-α and Src increases urea transporter A1 α-2,6 sialylation, Li X., B. Yang, M. Chen, J. Klein, Jeff. Sands, and G. Chen, 2015
Developing hypothetical inhibition mechanism of novel urea transporter B inhibitor, Li M., W.I. Tou, H. Zhou, F. Li, H. Ren, C.Y. Chen, and B. Yang, 2014
mPGES-2 deletion remarkably enhances liver injury in streptozotocin-treated mouse via induction of GLUT2, Sun Y., Z. Jia, G. Yang, Y. Kakizo, M. Liu, K.Yang, Y. Liu, B. Yang and T. Yang, 2014
A novel small-molecule thienoquinolin urea transporter inhibitor acts as a potential diuretic, Li F., T. Lei, J. Zhu, W. Wang, Y. Sun, J. Chen, Z. Dong, H. Zhou and B. Yang, 2013

Diuretics Renal Injury Repair Mechanisms Polycystic Kidney Disease Drug Development Urea Transporters Aquaporins Molecular Biology Cell Biology Pharmacology

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