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Tie Lu
Basic Medical Sciences
Peking University
Beijing
Language: English, Chinese
Immunology
Pharmacology
Tissue Repair
Molecular Targets
Drug Discovery
Macrophage Metabolism
Epigenetic Regulation
Diabetes
Wound Healing
Gpcr Targeting
Areas of Focus
- Immunopharmacology
- Molecular targets for tissue injury repair and new drug discovery
Work Experience
- 2008-present: Lecturer, Associate Professor, Doctoral Supervisor at Peking University Basic Medical School, Department of Pharmacology
Academic Background & Achievements
- 1999-2003: Bachelor's Degree from Peking University School of Pharmacy
- 2003-2008: PhD from Peking University Basic Medical School
- Visiting Scholar at Michigan State University, Department of Pharmacology & Toxicology (2007-2008)
Publications
- 5-Hydroxymethylcytosine profiles in plasma cell-free DNA reflect molecular characteristics of diabetic kidney disease, Tie Lu*, Lin Jian*, 2022
- Low-dose nifedipine rescues impaired endothelial progenitor cell-mediated angiogenesis in diabetic mice, Tie Lu*, Chen Alex F.*, Xie Hehui*, 2023
- Current strategies and progress for targeting the 'undruggable' transcription factors, Wu Dalei*, Tie Lu*, 2022
- Emodin prevents renal ischemia-reperfusion injury via suppression of CAMKII/DRP1-mediated mitochondrial fission, Tie Lu*, 2022
- A novel risk score predicts prognosis in melanoma: The combination of three tumor-infiltrating immune cells and four immune-related genes, Su Jing*, Tie Lu*, 2021
- FOXO1 inhibition prevents renal ischemia-reperfusion injury via cAMP-response element binding protein/PPAR-γ coactivator-1α-mediated mitochondrial biogenesis, Tie Lu*, 2020
- A brief guide to good practices in pharmacological experiments: Western blotting, Tie Lu*, Xiao Han*, Wu Dalei*, 2020
- FOXO1 inhibition potentiates endothelial angiogenic functions in diabetes via suppression of ROCK1/Drp1-mediated mitochondrial fission, Tie Lu*, 2018
- Curcumin attenuates palmitate-induced apoptosis in MIN6 pancreatic β-cells through PI3K/Akt/FoxO1 and mitochondrial survival pathways, Tie Lu*, Li Xuejun*, 2015
- Endothelial-specific BH4 expression preserves endothelial progenitor cells via suppressing TSP-1 expression in type 1 diabetes, Tie Lu, 2014
- Genistein accelerates refractory wound healing by suppressing superoxide and FoxO1/iNOS pathway in type 1 diabetes, Tie Lu, 2013
- Endothelial-specific tetrahydrobiopterin expression accelerates refractory wound healing by suppressing oxidative stress in diabetes, Tie Lu, 2009
- Epinephrine increases phosphorylation of MAP-2c in rat pheochromocytoma cells (PC12 cells) via a protein kinase C- and mitogen activated protein kinase-dependent mechanism, Tie Lu, 2008
