Professor | Tie Lu | Asia Growth Partners

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Name	Tie Lu
Contact Information	tielu@bjmu.edu.cn
Language ability	English, Chinese
Province	Beijing

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Name

Tie Lu

Contact Information

tielu@bjmu.edu.cn

Language ability

English, Chinese

Province

Beijing

University/Lab Affiliation and Title	Peking University
Faculty	Basic Medical Sciences
Academic Background & Achievements	1999-2003: Bachelor's Degree from Peking University School of Pharmacy 2003-2008: PhD from Peking University Basic Medical School Visiting Scholar at Michigan State University, Department of Pharmacology & Toxicology (2007-2008)
Work Experience	2008-present: Lecturer, Associate Professor, Doctoral Supervisor at Peking University Basic Medical School, Department of Pharmacology

University/Lab Affiliation and Title

Peking University

Faculty

Basic Medical Sciences

Academic Background & Achievements

1999-2003: Bachelor's Degree from Peking University School of Pharmacy
2003-2008: PhD from Peking University Basic Medical School
Visiting Scholar at Michigan State University, Department of Pharmacology & Toxicology (2007-2008)

Work Experience

2008-present: Lecturer, Associate Professor, Doctoral Supervisor at Peking University Basic Medical School, Department of Pharmacology

Areas of Focus	Immunopharmacology Molecular targets for tissue injury repair and new drug discovery
Publications	5-Hydroxymethylcytosine profiles in plasma cell-free DNA reflect molecular characteristics of diabetic kidney disease, Tie Lu, Lin Jian, 2022 Low-dose nifedipine rescues impaired endothelial progenitor cell-mediated angiogenesis in diabetic mice, Tie Lu, Chen Alex F., Xie Hehui, 2023 Current strategies and progress for targeting the 'undruggable' transcription factors, Wu Dalei, Tie Lu, 2022 Emodin prevents renal ischemia-reperfusion injury via suppression of CAMKII/DRP1-mediated mitochondrial fission, Tie Lu, 2022 A novel risk score predicts prognosis in melanoma: The combination of three tumor-infiltrating immune cells and four immune-related genes, Su Jing, Tie Lu, 2021 FOXO1 inhibition prevents renal ischemia-reperfusion injury via cAMP-response element binding protein/PPAR-γ coactivator-1α-mediated mitochondrial biogenesis, Tie Lu, 2020 A brief guide to good practices in pharmacological experiments: Western blotting, Tie Lu, Xiao Han, Wu Dalei, 2020 FOXO1 inhibition potentiates endothelial angiogenic functions in diabetes via suppression of ROCK1/Drp1-mediated mitochondrial fission, Tie Lu, 2018 Curcumin attenuates palmitate-induced apoptosis in MIN6 pancreatic β-cells through PI3K/Akt/FoxO1 and mitochondrial survival pathways, Tie Lu, Li Xuejun*, 2015 Endothelial-specific BH4 expression preserves endothelial progenitor cells via suppressing TSP-1 expression in type 1 diabetes, Tie Lu, 2014 Genistein accelerates refractory wound healing by suppressing superoxide and FoxO1/iNOS pathway in type 1 diabetes, Tie Lu, 2013 Endothelial-specific tetrahydrobiopterin expression accelerates refractory wound healing by suppressing oxidative stress in diabetes, Tie Lu, 2009 Epinephrine increases phosphorylation of MAP-2c in rat pheochromocytoma cells (PC12 cells) via a protein kinase C- and mitogen activated protein kinase-dependent mechanism, Tie Lu, 2008

Areas of Focus

Immunopharmacology
Molecular targets for tissue injury repair and new drug discovery

Publications

5-Hydroxymethylcytosine profiles in plasma cell-free DNA reflect molecular characteristics of diabetic kidney disease, Tie Lu*, Lin Jian*, 2022
Low-dose nifedipine rescues impaired endothelial progenitor cell-mediated angiogenesis in diabetic mice, Tie Lu*, Chen Alex F.*, Xie Hehui*, 2023
Current strategies and progress for targeting the 'undruggable' transcription factors, Wu Dalei*, Tie Lu*, 2022
Emodin prevents renal ischemia-reperfusion injury via suppression of CAMKII/DRP1-mediated mitochondrial fission, Tie Lu*, 2022
A novel risk score predicts prognosis in melanoma: The combination of three tumor-infiltrating immune cells and four immune-related genes, Su Jing*, Tie Lu*, 2021
FOXO1 inhibition prevents renal ischemia-reperfusion injury via cAMP-response element binding protein/PPAR-γ coactivator-1α-mediated mitochondrial biogenesis, Tie Lu*, 2020
A brief guide to good practices in pharmacological experiments: Western blotting, Tie Lu*, Xiao Han*, Wu Dalei*, 2020
FOXO1 inhibition potentiates endothelial angiogenic functions in diabetes via suppression of ROCK1/Drp1-mediated mitochondrial fission, Tie Lu*, 2018
Curcumin attenuates palmitate-induced apoptosis in MIN6 pancreatic β-cells through PI3K/Akt/FoxO1 and mitochondrial survival pathways, Tie Lu*, Li Xuejun*, 2015
Endothelial-specific BH4 expression preserves endothelial progenitor cells via suppressing TSP-1 expression in type 1 diabetes, Tie Lu, 2014
Genistein accelerates refractory wound healing by suppressing superoxide and FoxO1/iNOS pathway in type 1 diabetes, Tie Lu, 2013
Endothelial-specific tetrahydrobiopterin expression accelerates refractory wound healing by suppressing oxidative stress in diabetes, Tie Lu, 2009
Epinephrine increases phosphorylation of MAP-2c in rat pheochromocytoma cells (PC12 cells) via a protein kinase C- and mitogen activated protein kinase-dependent mechanism, Tie Lu, 2008

Immunology Pharmacology Tissue Repair Molecular Targets Drug Discovery Macrophage Metabolism Epigenetic Regulation Diabetes Wound Healing Gpcr Targeting

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