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铁璐
Basic Medical Sciences
北京大学
北京
Language: 英语, 汉语
免疫学
药理学
组织修复
分子靶点
药物发现
巨噬细胞代谢
表观遗传调控
糖尿病
伤口愈合
Gpcr靶向
Areas of Focus
- 免疫药理学
- 组织损伤修复的分子靶点及新药发现
Work Experience
- 2008年至今：北京大学基础医学院药理学系，讲师、副教授、博士生导师
Academic Background & Achievements
- 1999-2003年：北京大学药学院，学士
- 2003-2008年：北京大学基础医学院，博士
- 2007-2008年：美国密歇根州立大学药理&毒理学系，访问学者
Publications
- 5-Hydroxymethylcytosine profiles in plasma cell-free DNA reflect molecular characteristics of diabetic kidney disease, 铁璐*, 林健*, 2022
- Low-dose nifedipine rescues impaired endothelial progenitor cell-mediated angiogenesis in diabetic mice, 铁璐*, 陈亚历克斯 F.*, 谢和辉*, 2023
- Current strategies and progress for targeting the 'undruggable' transcription factors, 吴大磊*, 铁璐*, 2022
- Emodin prevents renal ischemia-reperfusion injury via suppression of CAMKII/DRP1-mediated mitochondrial fission, 铁璐*, 2022
- A novel risk score predicts prognosis in melanoma: The combination of three tumor-infiltrating immune cells and four immune-related genes, 苏静*, 铁璐*, 2021
- FOXO1 inhibition prevents renal ischemia-reperfusion injury via cAMP-response element binding protein/PPAR-γ coactivator-1α-mediated mitochondrial biogenesis, 铁璐*, 2020
- A brief guide to good practices in pharmacological experiments: Western blotting, 铁璐*, 肖涵*, 吴大磊*, 2020
- FOXO1 inhibition potentiates endothelial angiogenic functions in diabetes via suppression of ROCK1/Drp1-mediated mitochondrial fission, 铁璐*, 2018
- Curcumin attenuates palmitate-induced apoptosis in MIN6 pancreatic β-cells through PI3K/Akt/FoxO1 and mitochondrial survival pathways, 铁璐*, 李学军*, 2015
- Endothelial-specific BH4 expression preserves endothelial progenitor cells via suppressing TSP-1 expression in type 1 diabetes, 铁璐, 2014
- Genistein accelerates refractory wound healing by suppressing superoxide and FoxO1/iNOS pathway in type 1 diabetes, 铁璐, 2013
- Endothelial-specific tetrahydrobiopterin expression accelerates refractory wound healing by suppressing oxidative stress in diabetes, 铁璐, 2009
- Epinephrine increases phosphorylation of MAP-2c in rat pheochromocytoma cells (PC12 cells) via a protein kinase C- and mitogen activated protein kinase-dependent mechanism, 铁璐, 2008
