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Jing Zhang
Immunology and Metabolion
Wuhan University
Hubei
Language: Chinese, English
Metabolism
Cancer
Cellular
Signaling
Inflammation
Hypoxia
Mechanisms
Tumor
Research
Biology
Areas of Focus
- Tumor Metabolism
- Inflammation and Cell Signaling
- Tumor Hypoxia Mechanisms
Work Experience
- 2013-2017 - University of North Carolina at Chapel Hill, Cancer Research Center - Postdoctoral Researcher
- 2017-2019 - University of North Carolina at Chapel Hill, Department of Pathology/Cancer Research Center - Research Assistant Professor
- 2019- - Wuhan University, Medical Research Institute/Ministry of Education Center for Immunology and Metabolism - Professor
Academic Background & Achievements
- 2004-2008 Bachelor in Biological Sciences: Xiamen University
- 2008-2010 Master in Cell Biology: Wuhan University
- 2010-2013 PhD in Cell Biology: Wuhan University
Publications
- A mitochondrial EglN1-AMPKα axis drives breast cancer progression by enhancing metabolic adaptation to hypoxic stress, Jing Zhang et al., 2023
- A cleaved METTL3 potentiates the METTL3-WTAP 1 interaction and breast cancer progression, Jing Zhang et al., 2023
- FDXR drives primary and endocrine-resistant tumor cell growth in ER+ breast cancer via CPT1A-mediated fatty acid oxidation, Jing Zhang et al., 2023
- Alpha-Ketoglutarate-dependent enzymes in breast cancer and therapeutic implications, Jing Zhang et al., 2023
- Using Seahorse Machine to Measure OCR and ECAR in Cancer Cells, Jing Zhang et al., 2019
- VHL substrate transcription factor ZHX2 as an oncogenic driver in clear cell renal cell carcinoma, Jing Zhang et al., 2018
- VHL and Hypoxia Signaling: Beyond HIF in Cancer, Jing Zhang et al., 2018
- EglN2 Associates with NRF-PGC1α Complex and Controls Mitochondrial Function in Breast Cancer, Jing Zhang et al., 2015
- Death-associated protein kinase 1 is an IRF3/7-interacting protein that is involved in the cellular antiviral immune response, Jing Zhang et al., 2014
- TRIM32 protein modulates type I interferon induction and cellular antiviral response by targeting MITA/STING protein for K63-linked ubiquitination, Jing Zhang et al., 2012
Awards
- UNC Developmental Research Grant (2015)
- Department of Defense U.S. Breast Cancer Research Program Breakthrough Fellowship (2016)
- National Natural Science Foundation of China (2019, 2023)
- National Key R&D Program Young Scientist Project (Core Member, 2022)
- Hubei Province Natural Science Foundation Key Outstanding Youth Project (2020)
- Selected for Hubei Province 'BR Plan' (2020)
- Hubei Province Natural Science Foundation Group Project (Core Member, 2022)
