Professor | Hui Wang | Asia Growth Partners

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Name	Hui Wang
Contact Information	wanghui19@whu.edu.cn
Language ability	Chinese
Province	Hubei

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Name

Hui Wang

Contact Information

wanghui19@whu.edu.cn

Language ability

Chinese

Province

Hubei

University/Lab Affiliation and Title	Wuhan University
Faculty	Basic Medical Sciences
Academic Background & Achievements	2004.4 - 2004.7: Studied at National Education Administration College 1996.9 - 1999.6: PhD in Hepatic Pharmacology, Hubei Medical University 1988.9 - 1991.7: Master's in Pharmacology, Hubei Medical University 1981.9 - 1986.7: Bachelor of Medicine, Hubei Medical College
Work Experience	2012.12 - 2022.8: Second-level Professor, Doctoral Supervisor, Director of Provincial Key Laboratory, Department of Pharmacology, School of Basic Medical Sciences, Wuhan University 2000.4 - 2012.12: Professor, Doctoral Supervisor, Deputy Dean, Department of Pharmacology, School of Basic Medical Sciences, Wuhan University 1997.1 - 2000.3: Associate Professor, Department of Pharmacology, Hubei Medical University 1993.6 - 1996.12: Lecturer, Department of Pharmacology, Hubei Medical University 1991.6 - 1993.5: Assistant, Department of Pharmacology, Hubei Medical University 1986.7 - 1988.8: Resident Physician, Third Hospital of Wuhan
Awards	2019: Second Hubei Medical Leadership Talent Engineering Trainee and Hubei Famous Doctor Studio Head 2017: Wuhan University Teaching Master 2016: Luojia Outstanding Scholar of Wuhan University (re-awarded) 2016: Hubei Provincial Government Special Allowance 2014: Wuhan University President's Award for Outstanding Teaching Contribution 2014: Zhu Yubi Medical Prize of Wuhan University Medical Department 2013: Luojia Outstanding Scholar of Wuhan University 2013: Top Ten Moral Models of Wuhan University 2012: My Favorite Excellent Teacher Award of Wuhan University 2005: Wuhan City Science and Technology Rising Star 2001: Wuhan City Government Talent Special Allowance 2001: Baosteel Education Fund National Outstanding Teacher Award 2000: Servier National Young Pharmacologist Honor Title by the Chinese Pharmacological Society 1999: Hubei Provincial Higher Education Scientific Innovation and Achievement Transformation Promotion Award 1998: Third Prize in the Sixth National Young Teacher Award of the Fok Ying Tung Education Foundation

University/Lab Affiliation and Title

Wuhan University

Faculty

Basic Medical Sciences

Academic Background & Achievements

2004.4 - 2004.7: Studied at National Education Administration College
1996.9 - 1999.6: PhD in Hepatic Pharmacology, Hubei Medical University
1988.9 - 1991.7: Master's in Pharmacology, Hubei Medical University
1981.9 - 1986.7: Bachelor of Medicine, Hubei Medical College

Work Experience

2012.12 - 2022.8: Second-level Professor, Doctoral Supervisor, Director of Provincial Key Laboratory, Department of Pharmacology, School of Basic Medical Sciences, Wuhan University
2000.4 - 2012.12: Professor, Doctoral Supervisor, Deputy Dean, Department of Pharmacology, School of Basic Medical Sciences, Wuhan University
1997.1 - 2000.3: Associate Professor, Department of Pharmacology, Hubei Medical University
1993.6 - 1996.12: Lecturer, Department of Pharmacology, Hubei Medical University
1991.6 - 1993.5: Assistant, Department of Pharmacology, Hubei Medical University
1986.7 - 1988.8: Resident Physician, Third Hospital of Wuhan

Awards

2019: Second Hubei Medical Leadership Talent Engineering Trainee and Hubei Famous Doctor Studio Head
2017: Wuhan University Teaching Master
2016: Luojia Outstanding Scholar of Wuhan University (re-awarded)
2016: Hubei Provincial Government Special Allowance
2014: Wuhan University President's Award for Outstanding Teaching Contribution
2014: Zhu Yubi Medical Prize of Wuhan University Medical Department
2013: Luojia Outstanding Scholar of Wuhan University
2013: Top Ten Moral Models of Wuhan University
2012: My Favorite Excellent Teacher Award of Wuhan University
2005: Wuhan City Science and Technology Rising Star
2001: Wuhan City Government Talent Special Allowance
2001: Baosteel Education Fund National Outstanding Teacher Award
2000: Servier National Young Pharmacologist Honor Title by the Chinese Pharmacological Society
1999: Hubei Provincial Higher Education Scientific Innovation and Achievement Transformation Promotion Award
1998: Third Prize in the Sixth National Young Teacher Award of the Fok Ying Tung Education Foundation

Areas of Focus	Drug targets and new drug development Xenobiotic developmental toxicology
Publications	Metal-Drug Nanoparticles-Mediated Osteolytic Microenvironment Regulation for Enhanced Radiotherapy of Orthotopic Osteosarcoma, Geng H, Zhou MX, Li B, Liu L, Yang X, Wen YX, Yu HJ, Wang H, Chen J, Chen LB, 2021 Developmental toxicity and programming alterations of multiple organs in offspring induced by medication during pregnancy, Lu ZJ, Guo Y, Xu D, Xiao H, Kou H, Ao Y, Liu KX, Chen LB, Wang H, 2022 Hyperglycemia-induced accumulation of advanced glycosylation end products in fibroblast-like synoviocytes promotes knee osteoarthritis, Li QX, Wen YX, Wang LL, Chen B, Chen J, Wang H, Chen LB, 2021 P-gp expression inhibition mediates placental glucocorticoid barrier opening and fetal weight loss, Ge CY, Xu D, Yu PX, Fang M, Guo JJ, Xu D, Qiao Y, Chen SJ, Zhang YZ, Wang H, 2021 Dexamethasone induces an imbalanced fetal-placental-maternal bile acid circulation: Involvement of placental transporters, Huang W, Zhou J, Guo JJ, Hu W, Chen GH, Li B, Wen YJ, Jiang YM, Fu KL, Bi HC, Zhang YZ, Wang H, 2021 Prenatal dexamethasone exposure induced pancreatic β-cell dysfunction and glucose intolerance of male offspring rats: Role of the epigenetic repression of ACE2, Dai Y, Kou H, Gui S, Guo X, Liu H, Gong Z, Sun X, Wang H, Guo Y, 2022 Differential expression of placental 11β-HSD2 induced by high maternal glucocorticoid exposure mediates sex differences in placental and fetal development, Yu P, Zhou J, Ge C, Fang M, Zhang Y, Wang H, 2022 Maternally derived low glucocorticoid mediates adrenal developmental programming alteration in offspring induced by dexamethasone, Chen YW, Xia X, Fang M, Chen GH, Cao JG, Qu H, Wang H, 2021 H19/let-7 axis mediates caffeine exposure during pregnancy induced adrenal dysfunction and its multi-generation inheritance, He Z, Zhang JZ, Chen GH, Cao JG, Chen YW, Ai C, Wang H, 2021 Intrauterine endogenous high glucocorticoids program ovarian dysfunction in female offspring secondary to prenatal caffeine exposure, Lv F, Fan GL, Wan Y, Chen YX, Ni Y, Huang J, Xu D, Zhang W, Wang H, 2021 11β-Hydroxysteroid dehydrogenase 2: A key mediator of high susceptibility to osteoporosis in offspring after prenatal dexamethasone exposure, Wu Z, Wen Y, Xiao H, Zhu J, Li B, Shangguan Y, He H, Wang H, Chen L, 2022 miRNA320a-3p/RUNX2 signal programming mediates the transgenerational inheritance of inhibited ovarian estrogen synthesis in female offspring rats induced by prenatal dexamethasone exposure, Gong XH, Zhang JZ, Ge CY, Yi YW, Dai SY, Fan GL, Zhang YZ, Wang H, Xu D, 2021 Sex difference in adrenal developmental toxicity induced by dexamethasone and its intrauterine programming mechanism, Chen YW, Xu D, Xia X, Chen GH, Xiao H, Chen LB, Wang H, 2021 Programming changes in GLUT1 mediated the accumulation of AGEs and matrix degradation in the articular cartilage of female adult rats after prenatal caffeine exposure, Li QX, Wang LL, Wang YZ, Liu L, Han H, Chen LB, Wang H, 2020 The low-expression programming of 11β-HSD2 mediates osteoporosis susceptibility induced by prenatal caffeine exposure in male offspring rats, Xiao H, Wu ZX, Li B, Shangguan YF, Jean-François Stoltz, Jacques Magdalou, Chen LB , Wang H*, 2020

Areas of Focus

Drug targets and new drug development
Xenobiotic developmental toxicology

Publications

Metal-Drug Nanoparticles-Mediated Osteolytic Microenvironment Regulation for Enhanced Radiotherapy of Orthotopic Osteosarcoma, Geng H, Zhou MX, Li B, Liu L, Yang X, Wen YX, Yu HJ, Wang H*, Chen J*, Chen LB*, 2021
Developmental toxicity and programming alterations of multiple organs in offspring induced by medication during pregnancy, Lu ZJ, Guo Y, Xu D, Xiao H, Kou H, Ao Y, Liu KX, Chen LB*, Wang H*, 2022
Hyperglycemia-induced accumulation of advanced glycosylation end products in fibroblast-like synoviocytes promotes knee osteoarthritis, Li QX, Wen YX, Wang LL, Chen B, Chen J, Wang H*, Chen LB*, 2021
P-gp expression inhibition mediates placental glucocorticoid barrier opening and fetal weight loss, Ge CY, Xu D, Yu PX, Fang M, Guo JJ, Xu D, Qiao Y, Chen SJ, Zhang YZ*, Wang H*, 2021
Dexamethasone induces an imbalanced fetal-placental-maternal bile acid circulation: Involvement of placental transporters, Huang W, Zhou J, Guo JJ, Hu W, Chen GH, Li B, Wen YJ, Jiang YM, Fu KL, Bi HC*, Zhang YZ*, Wang H*, 2021
Prenatal dexamethasone exposure induced pancreatic β-cell dysfunction and glucose intolerance of male offspring rats: Role of the epigenetic repression of ACE2, Dai Y, Kou H, Gui S, Guo X, Liu H, Gong Z, Sun X, Wang H*, Guo Y*, 2022
Differential expression of placental 11β-HSD2 induced by high maternal glucocorticoid exposure mediates sex differences in placental and fetal development, Yu P, Zhou J, Ge C, Fang M, Zhang Y, Wang H*, 2022
Maternally derived low glucocorticoid mediates adrenal developmental programming alteration in offspring induced by dexamethasone, Chen YW, Xia X, Fang M, Chen GH, Cao JG, Qu H, Wang H*, 2021
H19/let-7 axis mediates caffeine exposure during pregnancy induced adrenal dysfunction and its multi-generation inheritance, He Z, Zhang JZ, Chen GH, Cao JG, Chen YW, Ai C, Wang H*, 2021
Intrauterine endogenous high glucocorticoids program ovarian dysfunction in female offspring secondary to prenatal caffeine exposure, Lv F, Fan GL, Wan Y, Chen YX, Ni Y, Huang J, Xu D, Zhang W*, Wang H*, 2021
11β-Hydroxysteroid dehydrogenase 2: A key mediator of high susceptibility to osteoporosis in offspring after prenatal dexamethasone exposure, Wu Z, Wen Y, Xiao H, Zhu J, Li B, Shangguan Y, He H, Wang H*, Chen L*, 2022
miRNA320a-3p/RUNX2 signal programming mediates the transgenerational inheritance of inhibited ovarian estrogen synthesis in female offspring rats induced by prenatal dexamethasone exposure, Gong XH, Zhang JZ, Ge CY, Yi YW, Dai SY, Fan GL, Zhang YZ, Wang H*, Xu D*, 2021
Sex difference in adrenal developmental toxicity induced by dexamethasone and its intrauterine programming mechanism, Chen YW, Xu D, Xia X, Chen GH, Xiao H, Chen LB*, Wang H*, 2021
Programming changes in GLUT1 mediated the accumulation of AGEs and matrix degradation in the articular cartilage of female adult rats after prenatal caffeine exposure, Li QX, Wang LL, Wang YZ, Liu L, Han H, Chen LB*, Wang H*, 2020
The low-expression programming of 11β-HSD2 mediates osteoporosis susceptibility induced by prenatal caffeine exposure in male offspring rats, Xiao H, Wu ZX, Li B, Shangguan YF, Jean-François Stoltz, Jacques Magdalou, Chen LB *, Wang H*, 2020

Drug Targets New Drug Development Xenobiotics Developmental Toxicology Drug Research Toxicology Pharmacology Drug Safety Drug Efficacy Medical Research

Jing Yang - Wuhan University

Ting Wang - Nanjing Medical University

Lei Cao - Nanjing Medical University

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