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Pingping Fang
Basic Medical Sciences
Wuhan University
Hubei
Language: English, Chinese
Genomics
Proteomics
Research Methods
Drug Resistance
Targeted Therapies
Treatment Strategies
Dna Damage
Gene Transcription
Regulation
Pharmacology
Areas of Focus
- Development of research methods in genomics and proteomics
- Study of drug resistance in targeted therapies and exploration of new targeted treatment strategies
Work Experience
- 2020.01-present Distinguished Associate Researcher, Department of Pharmacology, Basic Medical College, Wuhan University
- 2018.07-2018.12 Postdoctoral Researcher, Comprehensive Cancer Center, University of New Mexico
- 2017.08-2018.06 Visiting Scholar, Comprehensive Cancer Center, University of New Mexico
- 2013.08-2017.08 Teaching and Research Assistant, University of Kansas Medical Center
- 2011.11-2013.08 Laboratory Technician, Stowers Institute for Medical Research
- 2010.07-2011.06 Research Assistant, College of Life Sciences, Wuhan University
Academic Background & Achievements
- 2013-2018 PhD in Pharmacology, University of Kansas Medical Center
- 2008-2010 Master in Biochemistry and Molecular Biology, Wuhan University
- 2004-2008 Bachelor in Biotechnology, Weifang College
Publications
- CDK12 and Integrator-PP2A Complex Modulates LEO1 Phosphorylation for Processive Transcription Elongation, Qiu M., Yin Z., Wang H., Lei L., Li C., Cui Y., Dai R., Yang P., Xiang Y., Li Q., Lv J., Hu Z., Chen M., Zhou H., Fang, P.*, Xiao R.*, Liang K.*, 2023
- G-quadruplexes sense natural porphyrin metabolites for regulation of gene transcription and chromatin landscapes, Li C., Yin Z., Xiao R., Huang B., Cui Y., Wang H., Xiang Y., Wang L., Lei L., Ye J., Li T., Zhong Y., Guo F., Xia Y., Fang P.*, Liang K.*, 2022
- Discovery of Novel Bicyclic Phenylselenyl-Containing Hybrids: An Orally Bioavailable, Potential, and Multiacting Class of Estrogen Receptor Modulators against Endocrine-Resistant Breast Cancer, X. Deng, B. Xie, Q. Li, Y. Xiao, Z. Hu, X. Deng, P. Fang*, C. Dong*, H. Zhou*, J. Huang*, 2022
- Ligand-induced Native G-quadruplexes Stabilization Impairs Transcription Initiation, C. Li, H. Wang, Z. Yin, P. Fang, R. Xiao, Y. Xiang, W. Wang, Q. Li, B. Huang, J. Huang, K. Liang*, 2021
- Genomic Profiling of Native R-loops with a DNA-RNA Hybrid Recognition Sensor, K. Wang, H. Wang, C. Li, Z. Yin, R. Xiao, Q. Li, Y. Xiang, W. Wang, J. Huang, L. Chen, P. Fang*, K. Liang*, 2021
- Three-dimensional oxabicycloheptene sulfonate targets the homologous recombination and repair programmes through estrogen receptor alpha antagonism, J. Wu, J. Yan, P. Fang, H.B. Zhou, K. Liang*, J. Huang*, 2020
- Genome-scale CRISPR knockout screen identifies TIGAR as a modifier of PARP inhibitor sensitivity, Fang, P., De Souza, C., Minn, K., Chien, J*., 2019
- Olaparib-induced Adaptive Response Is Disrupted by FOXM1 Targeting that Enhances Sensitivity to PARP Inhibition, Fang, P., Madden, J.A., Neums, L., Moulder, R.K., Forrest, M.L., Chien, J*., 2018
