Professor | Yunjiao He | Asia Growth Partners

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Name	Yunjiao He
Contact Information	heyj@sustech.edu.cn
Language ability	Chinese, English
Province	Guangdong

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Name

Yunjiao He

Contact Information

heyj@sustech.edu.cn

Language ability

Chinese, English

Province

Guangdong

University/Lab Affiliation and Title	Southern University of Science and Technology
Faculty	Medical School
Academic Background & Achievements	1999.9-2003.6 Bachelor: Wuhan University, Pharmacy 2003.9-2006.6 Master: Wuhan University, Pharmaceutical Chemistry 2009.1-2013.10 PhD: Hong Kong Polytechnic University, Biochemistry and Molecular Biology
Work Experience	2006.07-2008.08 - WuXi AppTec, Drug Synthesis Researcher 2013.10-2014.07 - Hong Kong Polytechnic University, Research Assistant 2014.07-2016.07 - Hong Kong Polytechnic University, Postdoctoral Researcher 2016.09-2019.05 - Southern University of Science and Technology, Postdoctoral Researcher

University/Lab Affiliation and Title

Southern University of Science and Technology

Faculty

Medical School

Academic Background & Achievements

1999.9-2003.6 Bachelor: Wuhan University, Pharmacy
2003.9-2006.6 Master: Wuhan University, Pharmaceutical Chemistry
2009.1-2013.10 PhD: Hong Kong Polytechnic University, Biochemistry and Molecular Biology

Work Experience

2006.07-2008.08 - WuXi AppTec, Drug Synthesis Researcher
2013.10-2014.07 - Hong Kong Polytechnic University, Research Assistant
2014.07-2016.07 - Hong Kong Polytechnic University, Postdoctoral Researcher
2016.09-2019.05 - Southern University of Science and Technology, Postdoctoral Researcher

Areas of Focus	Structural Biology Glycochemistry
Publications	Targeting the potent Beclin 1-UVRAG coiled-coil interaction with designed peptides enhances autophagy and endolysosomal trafficking, Shuai Wu, Yunjiao He, et al., 2018 Modified Penicillin Molecule with Carbapenem-Like Stereochemistry Specifically Inhibits Class C beta-Lactamases, Xuehua Pan, Yunjiao He, et al., 2017 Crystallographic Snapshots of Class A beta-Lactamase Catalysis Reveal Structural Changes That Facilitate beta-Lactam Hydrolysis, Xuehua Pan, Yunjiao He, et al., 2017 Perturbing the General Base Residue Glu166 in the Active Site of Class A beta-Lactamase Leads to Enhanced Carbapenem Binding and Acylation, Xuehua Pan, Yunjiao He, et al., 2014 A general and facile synthetic approach to N-alpha-Boc ureidoalanine derivatives, Teng H., Yunjiao He, et al., 2006 Novel intermediates in the active site of Class A β-lactamase reveal critical factors that coordinate the catalytic water molecule for nucleophilic attack on β-lactam acyl adduct, Yunjiao He, Lei J., Pan X., Huang X., Zhao Y., 2019

Areas of Focus

Structural Biology
Glycochemistry

Publications

Targeting the potent Beclin 1-UVRAG coiled-coil interaction with designed peptides enhances autophagy and endolysosomal trafficking, Shuai Wu, Yunjiao He, et al., 2018
Modified Penicillin Molecule with Carbapenem-Like Stereochemistry Specifically Inhibits Class C beta-Lactamases, Xuehua Pan, Yunjiao He, et al., 2017
Crystallographic Snapshots of Class A beta-Lactamase Catalysis Reveal Structural Changes That Facilitate beta-Lactam Hydrolysis, Xuehua Pan, Yunjiao He, et al., 2017
Perturbing the General Base Residue Glu166 in the Active Site of Class A beta-Lactamase Leads to Enhanced Carbapenem Binding and Acylation, Xuehua Pan, Yunjiao He, et al., 2014
A general and facile synthetic approach to N-alpha-Boc ureidoalanine derivatives, Teng H., Yunjiao He, et al., 2006
Novel intermediates in the active site of Class A β-lactamase reveal critical factors that coordinate the catalytic water molecule for nucleophilic attack on β-lactam acyl adduct, Yunjiao He, Lei J., Pan X., Huang X., Zhao Y., 2019

Protein Structure Enzymes Carbohydrates Molecular Interaction X-Ray Crystallography Nmr Spectroscopy Bioinformatics Molecular Dynamics Drug Design Biomolecular Engineering

Yunjiao He - Southern University of Science and Technology

Zhang Kuo - Southern University of Science and Technology

Hualiang Jiang - University of Chinese Academy of Sciences

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